Santosh Pandey

Prof. Santosh Pandey

Iowa State University, Ames, Iowa, USA
orcid

Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 September 2021 in Advanced Intelligent Systems
Verified
Journal Article
Open access
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VPVishal Patel
Vishal Patel
ACAustin Chesmore
Austin Chesmore
CLChristopher M. Legner
Christopher M. Legner
Santosh PandeySantosh Pandey
Santosh Pandey
The workplace influences the safety, health, and productivity of workers at multiple levels. To protect and promote total worker health, smart hardware, and software tools have emerged for the identification, elimination, substitution, and control of occupational hazards. Wearable devices enable constant monitoring of individual workers and the environment, whereas connected worker solutions provide contextual information and decision support. Here, the recent trends in commercial workplace technologies to monitor and manage occupational risks, injuries, accidents, and diseases are reviewed. Workplace safety wearables for safe lifting, ergonomics, hazard identification, sleep monitoring, fatigue management, and heat and cold stress are discussed. Examples of workplace productivity wearables for asset tracking, augmented reality, gesture and motion control, brain wave sensing, and work stress management are given. Workplace health wearables designed for work‐related musculoskeletal disorders, functional movement disorders, respiratory hazards, cardiovascular health, outdoor sun exposure, and continuous glucose monitoring are shown. Connected worker platforms are discussed with information about the architecture, system modules, intelligent operations, and industry applications. Predictive analytics provide contextual information about occupational safety risks, resource allocation, equipment failure, and predictive maintenance. Altogether, these examples highlight the ground‐level benefits of real‐time visibility about frontline workers, work environment, distributed assets, workforce efficiency, and safety compliance.

1 September 2019 in Sensors and Actuators A: Physical
Verified
Journal Article
Closed access
CLChristopher Legner
Christopher Legner
UKUpender Kalwa
Upender Kalwa
VPVishal Patel
Vishal Patel
ACAustin Chesmore
Austin Chesmore
Santosh PandeySantosh Pandey
Santosh Pandey

6 June 2011 in Lab on a Chip
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Journal Article
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JCJohn A. Carr
John A. Carr
APArchana Parashar
Archana Parashar
RGRichard Gibson
Richard Gibson
ARAlan P. Robertson
Alan P. Robertson
RMRichard Martin
Richard Martin
Santosh PandeySantosh Pandey
Santosh Pandey
This paper describes a new microfluidic platform for screening drugs and their dose response on the locomotion behavior of free living nematodes and parasitic nematodes. The system offers a higher sensitivity drug screening chip which employs a combination of existing and newly developed methods. Real-time observation of the entire drug application process (i.e. the innate pre-exposure locomotion, the transient response during drug exposure and the time-resolved, post-exposure behavior) at a single worm resolution is made possible. The chip enables the monitoring of four nematode parameters (number of worms responsive, number of worms leaving the drug well, average worm velocity and time until unresponsiveness). Each parameter generates an inherently different dose response; allowing for a higher resolution when screening for resistance. We expect this worm chip could be used as a robust cross species, cross drug platform. Existing nematode motility and migration assays do not offer this level of sophistication. The device comprises two principal components: behavioral microchannels to study nematode motility and a drug well for administering the dose and observing drug effects as a function of exposure time. The drug screening experiment can be described by three main steps: (i) ‘pre-exposure study’ – worms are inserted into the behavioral channels and their locomotion is characterized, (ii) ‘dose exposure’ – worms are guided from the behavioral microchannels into the drug well and held for a predefined time, during which time their transient response to the dose is characterized and (iii) ‘post-exposure study’ – worms are guided back into the behavioral microchannels where their locomotion (i.e. their time-resolved response to the dose) is characterized and compared to pre-exposure motility. The direction of nematodes' movement is reliably controlled by the application of an electric field within a defined range. Control experiments (e.g. in the absence of any drug) confirm that the applied electric fields do not affect the worms' motility or viability. We demonstrate the workability of the microfluidic platform on free living Caenorhabditis elegans (wild-type N2 and levamisole resistant ZZ15 lev-8) and parasitic Oesophagotomum dentatum (levamisole-sensitive, SENS and levamisole-resistant, LEVR) using levamisole (a well-studied anthelmintic) as the test drug. The proposed scheme of drug screening on a microfluidic device is expected to significantly improve the resolution, sensitivity and data throughput of in vivo testing, while offering new details on the transient and time-resolved exposure effects of new and existing anthelmintics.


10 September 2021 in Animals
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Journal Article
Open access
PDF file
Santosh PandeySantosh Pandey
Santosh Pandey
UKUpender Kalwa
Upender Kalwa
TKTaejoon Kong
Taejoon Kong
BGBaoqing Guo
Baoqing Guo
PGPhil Gauger
Phil Gauger
KYKyoung-Jin Yoon
Kyoung-Jin Yoon
Precision swine production can benefit from autonomous, noninvasive, and affordable devices that conduct frequent checks on the well-being status of pigs. Here, we present a remote monitoring tool for the objective measurement of some behavioral indicators that may help in assessing the health and welfare status—namely, posture, gait, vocalization, and external temperature. The multiparameter electronic sensor board is characterized by laboratory measurements and by animal tests. Relevant behavioral health indicators are discussed for implementing machine learning algorithms and decision support tools to detect animal lameness, lethargy, pain, injury, and distress. The roadmap for technology adoption is also discussed, along with challenges and the path forward. The presented technology can potentially lead to efficient management of farm animals, targeted focus on sick animals, medical cost savings, and less use of antibiotics.

27 June 2011 in Applied Physics Letters
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Journal Article
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APArchana Parashar
Archana Parashar
Santosh PandeySantosh Pandey
Santosh Pandey
We report a microfluidic platform for the hydroponic growth of Arabidopsis plants with high-resolution visualization of root development and root-pathogen interactions. The platform comprises a set of parallel microchannels with individual input/output ports where 1-day old germinated seedlings are initially placed. Under optimum conditions, a root system grows in each microchannel and its images are recorded over a 198-h period. Different concentrations of plant growth media show different root growth characteristics. Later, the developed roots are inoculated with two plant pathogens (nematodes and zoospores) and their physicochemical interactions with the live root systems are observed.