Maria Laura Schillirò

Dr. Maria Laura Schillirò

Aorn cardarelli
orcid
Department of General and Emergency Radiology - AORN A. Card...

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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10 April 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
FIFrancesca Iacobellis
Francesca Iacobellis
MSMarco Di Serafino
Marco Di Serafino
CRCamilla Russo
Camilla Russo
RRRoberto Ronza
Roberto Ronza
MCMartina Caruso
Martina Caruso
LRLuigia Romano
Luigia Romano
Gadolinium-based contrast agents (GBCAs) have helped to improve the role of magnetic resonance imaging (MRI) for the diagnosis and treatment of diseases. There are currently nine different commercially available gadolinium-based contrast agents (GBCAs) that can be used for body MRI cases, and which are classifiable according to their structures (cyclic or linear) or biodistribution (extracellular-space agents, target/specific-agents, and blood-pool agents). The aim of this review is to illustrate the commercially available MRI contrast agents, their effect on imaging, and adverse reaction on the body, with the goal to lead to their proper selection in different clinical contexts. When we have to choose between the different GBCAs, we have to consider several factors: (1) safety and clinical impact; (2) biodistribution and diagnostic application; (3) higher relaxivity and better lesion detection; (4) higher stability and lower tissue deposit; (5) gadolinium dose/concentration and lower volume injection; (6) pulse sequences and protocol optimization; (7) higher contrast-to-noise ratio at 3.0 T than at 1.5 T. Knowing the patient’s clinical information, the relevant GBCAs properties and their effect on body MRI sequences are the key features to perform efficient and high-quality MRI examination.

23 September 2022 in Tomography
Verified
Journal Article
Open access
PDF file
MSMarco Di Serafino
Marco Di Serafino
FIFrancesca Iacobellis
Francesca Iacobellis
MSMaria Laura Schillirò
Maria Laura Schillirò
GOGiuseppina Dell'Aversano Orabona
Giuseppina Dell'Aversano Orabona
AMAlberto Martino
Alberto Martino
LRLuigia Romano
Luigia Romano
Gastrointestinal bleeding is a potentially life-threatening abdominal emergency that remains a common cause of hospitalisation. Although 80–85% of cases of gastrointestinal bleeding resolve spontaneously, it can result in massive haemorrhage and death. The presentation of gastrointestinal bleeding can range from asymptomatic or mildly ill patients requiring only conservative treatments to severely ill patients requiring immediate intervention. Identifying the source of the bleeding can be difficult due to the wide range of potential causes, the length of the gastrointestinal tract and the intermittent nature of the bleeding. The diagnostic and therapeutic approach is fully dependent on the nature of the bleeding and the patient’s haemodynamic status. Radiologists should be aware of the appropriate uses of computed tomography angiography and other imaging modalities in patients with acute gastrointestinal bleeding, as well as the semiotics of bleeding and diagnostic pitfalls in order to appropriately diagnose and manage these patients. The learning objective of this review is to illustrate the computed tomography angiography technique, including the potential role of dual-energy computed tomography angiography, also highlighting the tips and tricks to identify the most common and uncommon features of acute gastrointestinal bleeding and its obscure form.

4 March 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
MSMarco Di Serafino
Marco Di Serafino
FIFrancesca Iacobellis
Francesca Iacobellis
MSMaria Laura Schillirò
Maria Laura Schillirò
DDDivina D'Auria
Divina D'Auria
Francesco VerdeFrancesco Verde
Francesco Verde
LRLuigia Romano
Luigia Romano
Errors in emergency ultrasound (US) have been representing an increasing problem in recent years thanks to several unique features related to both the inherent characteristics of the discipline and to the latest developments, which every medical operator should be aware of. Because of the subjective nature of the interpretation of emergency US findings, it is more prone to errors than other diagnostic imaging modalities. The misinterpretation of US images should therefore be considered as a serious risk in diagnosis. The etiology of error is multi-factorial: it depends on environmental factors, patients and the technical skills of the operator; it is influenced by intrinsic US artifacts, poor clinical correlation, US-setting errors and anatomical variants; and it is conditioned by the lack of a methodologically correct clinical approach and excessive diagnostic confidence too. In this review, we evaluate the common and uncommon sources of diagnostic errors in emergency US during clinical practice, showing how to recognize and avoid them.

8 February 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
MSMarco Di Serafino
Marco Di Serafino
FIFrancesca Iacobellis
Francesca Iacobellis
MSMaria Laura Schillirò
Maria Laura Schillirò
RRRoberto Ronza
Roberto Ronza
Francesco VerdeFrancesco Verde
Francesco Verde
LRLuigia Romano
Luigia Romano
Trauma is one of the most common causes of death or permanent disability in young people, so a timely diagnostic approach is crucial. In polytrauma patients, CEUS (contrast enhanced ultrasound) has been shown to be more sensitive than US (ultrasound) for the detection of solid organ injuries, improving the identification and grading of traumatic abdominal lesions with levels of sensitivity and specificity similar to those seen with MDCT (multidetector tomography). CEUS is recommended for the diagnostic evaluation of hemodynamically stable patients with isolated blunt moderate-energy abdominal traumas and the diagnostic follow-up of conservatively managed abdominal traumas. In this pictorial review, we illustrate the advantages and disadvantages of CEUS and the procedure details with tips and tricks during the investigation of blunt moderate-energy abdominal trauma as well as during follow-up in non-operative management.

16 November 2022 in Journal of Ultrasound
Verified
Journal Article
Closed access
PDF file
CRChiara Rinaldo
Chiara Rinaldo
DGDario Grimaldi
Dario Grimaldi
MSMarco Di Serafino
Marco Di Serafino
FIFrancesca Iacobellis
Francesca Iacobellis
Francesco VerdeFrancesco Verde
Francesco Verde
LRLuigia Romano
Luigia Romano

5 March 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
MCMartina Caruso
Martina Caruso
GOGiuseppina Dell'Aversano Orabona
Giuseppina Dell'Aversano Orabona
MSMarco Di Serafino
Marco Di Serafino
FIFrancesca Iacobellis
Francesca Iacobellis
Francesco VerdeFrancesco Verde
Francesco Verde
LRLuigia Romano
Luigia Romano
Pelvic pain (PP) is common in pregnant women and can be caused by several diseases, including obstetrics, gynaecological, gastrointestinal, genitourinary, and vascular disorders. Timely and accurate diagnosis as well as prompt treatment are crucial for the well-being of the mother and foetus. However, these are very challenging. It should be considered that the physiological changes occurring during pregnancy may confuse the diagnosis. In this setting, ultrasound (US) represents the first-line imaging technique since it is readily and widely available and does not use ionizing radiations. In some cases, US may be conclusive for the diagnosis (e.g., if it detects no foetal cardiac activity in suspected spontaneous abortion; if it shows an extrauterine gestational sac in suspected ectopic pregnancy; or if it reveals a dilated, aperistaltic, and blind-ending tubular structure arising from the cecum in suspicious of acute appendicitis). Magnetic resonance imaging (MRI), overcoming some limits of US, represents the second-line imaging technique when an US is negative or inconclusive, to detect the cause of bowel obstruction, or to characterize adnexal masses.