On 3 March 2021, a strong shallow earthquake affected northern Thessaly, Greece, with an epicenter close to Damasi village causing significant destruction of many stone houses. In this contribution, we provide fieldwork observations, satellite radar interferometry, mapping of the active faults exposed in the epicentral area, liquefactions and coseismic surface ruptures, and preliminary geomorphological analyses of the epicentral area. The geomorphological analysis is based on air photographs, digital surface models analysis, Real-Time Kinematik (RTK) measurements with Global Navigation Satellite System (GNSS) receivers, and data from UAV flight campaigns. Although the seismotectonic setting of the area is complex and there is an apparent mismatch between field and interferometric data, the results of our investigations suggest that at least three fault segments were reactivated by the major shocks of the March seismic sequence. These tectonic structureslikely represent the westward propagation of the Tyrnavos Graben, where newly formed and inherited low-angle faults interplay in a complex manner.