Climate change presents a major threat to water and sanitation services. There is an urgent need to understand and improve resilience, particularly in rural communities and small towns in low- and middle-income countries that already struggle to provide universal access to services and face increasing threats from climate change. To date, there is a lack of a simple framework to assess the resilience of water and sanitation services which hinders the development of strategies to improve services. An interdisciplinary team of engineers and environmental and social scientists were brought together to investigate the development of a resilience measurement framework for use in low- and middle-income countries. Six domains of interest were identified based on a literature review, expert opinion, and limited field assessments in two countries. A scoring system using a Likert scale is proposed to assess the resilience of services and allow analysis at local and national levels to support improvements in individual supplies, identifying systematic faults, and support prioritisation for action. This is a simple, multi-dimensional framework for assessing the resilience of rural and small-town water and sanitation services in LMICs. The framework is being further tested in Nepal and Ethiopia and future results will be reported on its application.

This article considers the degree to which achieving equity in Global North–South research partnerships is possible under current UK funding models. While there has been significant discussion with respect to the decolonisation of research, it will be argued that there is some distance between the language of equity articulated currently by UK funding bodies, and the realities of working as a project partner in the Global South. The article draws on the prior and ongoing experiences of a multidisciplinary team of researchers brought together by a UK-funded research project. In the interests of moving towards more equitable systems of knowledge production and dissemination, it explores the power asymmetries that can be inherent in Global North–South research partnerships, and the extent to which issues of coloniality continue to shape aspects of research agenda setting, project framing, impact, academic publishing and the division of labour within partnerships.

Understanding the resilience of water supplies to climate change is becoming an urgent priority to ensure health targets are met. Addressing systemic issues and building the resilience of community-managed supplies, which serve millions of people in rural LMIC settings, will be critical to improve access to safe drinking water. The How Tough is WASH (HTIW) framework to assess resilience was applied to community-managed water supplies in Ethiopia and Nepal to assess the effectiveness of this framework in field conditions. The resilience of these water supplies was measured along six domains—the environment, infrastructure, management, institutional support, community governance and supply chains—that can affect how they respond to climate change effects. We found that the HTIW framework provided an objective measure of resilience and could be used to rank water supplies in order of priority for action. We also found that systemic issues could be identified. The tools and methods used in the framework were easy to deploy by field research teams. The water supplies studied in Ethiopia and Nepal had low to moderate resilience to climate change. Service management and institutional support were weak in both countries. The data from Ethiopia and Nepal suggests that many water supplies in rural and small-town communities are unlikely to be resilient to future climate change without increased investment and support. The use of simple frameworks such as HTIW will be important in supporting decisions around such investments by identifying priority communities and actions.

This article makes a case for a reconceptualisation of aid and development programme design. Specifically, it questions the role of the international “development expert” in the design and implementation process. We argue that by employing “design thinking” as a guiding principle, the way in which aid programmes are envisaged and delivered can be radically overhauled, resulting in dramatically improved outcomes for the users of aid. We argue that practical improvements in delivery are achievable through locally rooted, “user-driven” development solutions that originate from the beneficiaries themselves. Design thinking as applied here goes significantly further than other programme design and implementation methodologies that champion locally owned, needs-driven assistance. Furthermore, we make a case for this approach addressing wider problems within the sector, namely the perception, in some quarters, that aid is intrinsically “neo-imperialist” in design and ideologically driven.

Background: Ghana is endemic for some neglected tropical diseases (NTDs) including schistosomiasis, onchocerciasis and lymphatic filariasis. The major intervention for these diseases is mass drug administration of a few repeatedly recycled drugs which is a cause for major concern due to reduced efficacy of the drugs and the emergence of drug resistance. Evidently, new treatments are needed urgently. Medicinal plants, on the other hand, have a reputable history as important sources of potent therapeutic agents in the treatment of various diseases among African populations, Ghana inclusively, and provide very useful starting points for the discovery of much-needed new or alternative drugs.Methodology/Principal findings: In this study, extracts of fifteen traditional medicines used for treating various NTDs in local communities were screenedin vitrofor efficacy against schistosomiasis, onchocerciasis and African trypanosomiasis. Two extracts, NTD-B4-DCM and NTD-B7-DCM, prepared from traditional medicines used to treat schistosomiasis, displayed the highest activity (IC₅₀= 30.5 μg/mL and 30.8 μg/mL, respectively) againstSchistosoma mansoniadult worms. NTD-B2-DCM, also obtained from an antischistosomal remedy, was the most active against female and male adultOnchocera ochengiworms (IC₅₀= 76.2 μg/mL and 76.7 μg/mL, respectively). Antitrypanosomal assay of the extracts againstTrypanosoma brucei bruceigave the most promising results (IC₅₀= 5.63 μg/mL to 18.71 μg/mL). Incidentally, NTD-B4-DCM and NTD-B2-DCM, also exhibited the greatest antitrypanosomal activities (IC₅₀= 5.63 μg/mL and 7.12 μg/mL, respectively). Following the favourable outcome of the antitrypanosomal screening, this assay was selected for bioactivity-guided fractionation. NTD-B4-DCM, the most active extract, was fractionated and subsequent isolation of bioactive constituents led to an eupatoriochromene-rich oil (42.6%) which was 1.3-fold (IC₅₀<0.0977 μg/mL) more active than the standard antitrypanosomal drug, diminazene aceturate (IC₅₀= 0.13 μg/mL).Conclusion/Significance: These findings justify the use of traditional medicines and demonstrate their prospects towards NTDs drug discovery.

The WTO-sanctioned waiver for the extension of the Lomé system of preferences to the African, Caribbean Pacific (ACP) countries expired in December 2007. This deadline coincided with the scheduled conclusion of the EU–ACP Economic Partnership Agreement (EPA) negotiations, initiated in 2002. The origins of the EU–ACP relationship stretch back to the early days of the European Community, and were formalised in 1975 with the signing of the Georgetown Agreement. However, there has been a notable ‘cooling’ of the relationship since the signing of the Cotonou Partnership Agreement in 2000. For many, the new EPA framework is perceived as a diktat rather than a true partnership agreement. This article reviews the culmination of six years of talks between the two sides and the EU's apparent ‘rationalisation’ of a decades-old partnership.