Piero Cascone

Piero Cascone

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Piero Cascone

Department of Oral and Maxillofacial Sciences, School of Dentistry, "Sapienza" University of Rome, Via Caserta, 6 00161 Rome, Italy

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 December 2019 in Italian Journal of Pediatrics
Verified
Journal Article
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Maria Grazia CagettiMaria Grazia Cagetti
Maria Grazia Cagetti
PMPiero Alessandro Marcoli
Piero Alessandro Marcoli
MBMario Berengo
Mario Berengo
PCPiero Cascone
Piero Cascone
LCLivio Cordone
Livio Cordone
SZStefania Zampogna
Stefania Zampogna
Dental trauma is a frequent occurrence in children and adolescent and a correct diagnosis and treatment are essential for a favourable long-term prognosis. The present Guidelines aim to formulate evidence-based recommendations to assist dentists, paediatricians, surgeons, teachers, school and sport staff, parents in the prevention and first aid of dental trauma in children and to provide a careful assessment of the medico-legal implications, reviewing the first draft of the guidelines published in 2012. A multidisciplinary panel on the behalf of the Italian Ministry of Health and in collaboration with the WHO Collaborating Centre for Epidemiology and Community Dentistry of Milan, developed this document. The following four queries were postulated: 1) Which kind of precautions the health personnel, parents, sports and educational personnel must activate in order to prevent the dental trauma damage? 2) How an orofacial trauma in paediatric patients should be managed either in the Emergency Care Unit and/or in private dental office? 3) What criteria should be adopted by a dentist private practitioner to fill in a certificate in cases of dental and/or tempomandibular joint trauma occurring in children and adolescents? 4) What are the elements that should lead clinicians to suspect a non-accidental dental trauma? A systematic review and analysis of the scientific literature published in English, Italian and French from 2007 to 2017 regarding dental trauma in children and adolescents aged 0–18 years was performed, and about 100 papers were analysed and included. The following four domains were analysed and discussed: Dental Trauma Prevention Strategies and Health Education, First aid in orofacial and dental trauma, Certificate of the dental trauma, Oral and dental signs of child abuse and neglect. Twenty-eight recommendations were draw up and codified by the panel according to the Methodological handbook, produced by the Istituto Superiore di Sanità, in order to guide physicians in the prevention and first aid of dental trauma in children and adolescents. In addition, a careful assessment of the medico-legal implications is reported in this document.

1 May 2008 in Journal of Craniofacial Surgery
Verified
Journal Article
Closed access
PCPiero Mds Cascone
Piero Mds Cascone
BPBernardino Petrucci
Bernardino Petrucci
Valerio RamieriValerio Ramieri
Valerio Ramieri
MTMarianetti TitoMatteo
Marianetti TitoMatteo
Among professional [soccer] players, a relevant incidence of maxillofacial trauma has been reported. The main challenge in these particular patients is to give them the possibility of a very short convalescence period and to make possible their agonistic activity as soon as possible. The authors here present an innovative technique to realize this-the Security Hi-tech Individual Extra-Light Device Mask, a customizable protective shield based on the player's face cast. A completely customized mask was forged over the player's face cast to protect the injured area. This mask shortens convalescence period, and due to its realization, it is comfortable and easy fitting, thus allowing the player to perform at a professional level in his sport activity in the shortest time possible.

Verified
Journal Article
Open access
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MAMichele Runci Anastasi
Michele Runci Anastasi
PCPiero Cascone
Piero Cascone
Giuseppe Pio AnastasiGiuseppe Pio Anastasi
Giuseppe Pio Anastasi
GSGiuseppe Santoro
Giuseppe Santoro
FNFabiana Nicita
Fabiana Nicita
GCGiuseppina Cutroneo
Giuseppina Cutroneo
The extracellular matrix of the articular disc in a temporomandibular joint (TMJ) is composed mainly of collagen I and elastin. The collagen is important for resisting tensile forces, while the elastin is responsible to maintain the shape after deformation. We studied the orientation of collagen and elastin in a normal human temporomandibular joint disc by light microscopy, immunofluorescence and scanning electron microscopy. Our results demonstrated that collagen and elastin run parallel to each other in the intermediate zone with an anteroposterior orientation. From here, the orientation of two fibers groups changes into a disordered arrangement in the transition zone. Numerous elastic fibers cross with the collagen fibers, defining an interwoven knitted arrangement. The evaluation of the disc–condyle relationship shows that the medial margin of the articular disc is inserted directly at the superficial layer of the mandibular condylar cartilage. Therefore, the tensile properties of the TMJ disc are expressed in the directions corresponding to the orientation of the collagen fibers, and the complex orientation of elastin with the collagen determines the maintaining of the shape after the stresses by the joint movements. Moreover, the direct anatomical relationship between the articular disc and the mandibular condyle makes a decisive contribution to the understanding of TMJ movements.

7 April 2021 in Medicina
Verified
Journal Article
Open access
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CSCinzia Sindona
Cinzia Sindona
MAMichele Runci Anastasi
Michele Runci Anastasi
LCLuigi Chiricosta
Luigi Chiricosta
AGAgnese Gugliandolo
Agnese Gugliandolo
SSSerena Silvestro
Serena Silvestro
EMEmanuela Mazzon
Emanuela Mazzon
Background and Objectives: Musculoskeletal injuries represent a pathological condition due to limited joint motility and morphological and functional alterations of the muscles. Temporomandibular disorders (TMDs) are pathological conditions due to alterations in the musculoskeletal system. TMDs mainly cause temporomandibular joint and masticatory muscle dysfunctions following trauma, along with various pathologies and inflammatory processes. TMD affects approximately 15% of the population and causes malocclusion problems and common symptoms such as myofascial pain and migraine. The aim of this work was to provide a transcriptomic profile of masticatory muscles obtained from TMD migraine patients compared to control. Materials and Methods: We used Next Generation Sequencing (NGS) technology to evaluate transcriptomes in masseter and temporalis muscle samples. Results: The transcriptomic analysis showed a prevalent downregulation of the genes involved in the myogenesis process. Conclusions: In conclusion, our findings suggest that the muscle regeneration process in TMD migraine patients may be slowed, therefore therapeutic interventions are needed to restore temporomandibular joint function and promote healing processes.

Verified
Journal Article
Open access
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MAMichele Runci Anastasi
Michele Runci Anastasi
Antonio CentofantiAntonio Centofanti
Antonio Centofanti
AAAlba Arco
Alba Arco
GVGiovanna Vermiglio
Giovanna Vermiglio
FNFabiana Nicita
Fabiana Nicita
GCGiuseppina Cutroneo
Giuseppina Cutroneo
The temporomandibular joint (TMJ) is a bilateral synovial articulation stabilized by several anatomical structures such as ligaments. The existence of articular capsule reinforcement structures have been described in the lateral and medial sides of disc which have been defined as collateral ligaments, lateral and medial. Despite that, some macroscopic observations support that these collateral ligaments do not belong to the articular capsule but they belong to the disc. By that, the aim of the present work was to evaluate morphological aspects of TMJ from cadaveric frozen heads by histological and immunofluorescence techniques in order to verify the origin and insertion of lateral and medial collateral ligaments. Results show that both lateral and medial ligaments origin from the disc and insert directly to the articular cartilage of mandibula condyle. These data open a new approach in the study of human TMJ.

30 October 2022 in Journal of Stomatology Oral and Maxillofacial Surgery
Verified
Journal Article
Closed access
RVRoberto Antonio Vernucci
Roberto Antonio Vernucci
VMValentina Mazzoli
Valentina Mazzoli
VIVeronica Incisivo
Veronica Incisivo
RGRosanna Guarnieri
Rosanna Guarnieri
PCPiero Cascone
Piero Cascone
Gabriella GalluccioGabriella Galluccio
Gabriella Galluccio