In this paper, we propose using mobile nanosensors (MNSs) for early stage anomaly detection. For concreteness, we focus on the detection of cancer cells located in a particular region of a blood vessel. These cancer cells produce and emit special molecules, so-called biomarkers, which are symptomatic for the presence of anomaly, into the cardiovascular system. Detection of cancer biomarkers with conventional blood tests is difficult in the early stages of a cancer due to the very low concentration of the biomarkers in the samples taken. However, close to the cancer cells, the concentration of the cancer biomarkers is high. Hence, detection is possible if a sensor with the ability to detect these biomarkers is placed in the vicinity of the cancer cells. Therefore, in this paper, we study the use of MNSs that are injected at a suitable injection site and can move through the blood vessels of the cardiovascular system, which potentially contain cancer cells. These MNSs can be activated by the biomarkers close to the cancer cells, where the biomarker concentration is sufficiently high. Eventually, the MNSs are collected by a fusion center (FC) where their activation levels are read and exploited to declare the presence of anomaly. We analytically derive the biomarker concentration in a network of interconnected blood vessels as well as the probability mass function of the MNSs’ activation levels and validate the obtained results via particle-based simulations. Then, we derive the optimal decision rule for the FC regarding the presence of anomaly assuming that the entire network is known at the FC. Finally, for the FC, we propose a simple sum detector that does not require knowledge of the network topology. Our simulations reveal that while the optimal detector achieves a higher performance than the sum detector, both proposed detectors significantly outperform a benchmark scheme that uses fixed nanosensors at the FC.

While ISI is a common issue in classical communications, it is more challenging and prominent in the context of molecular communication because one cannot readily combat ISI with classical channel equalization techniques. This is due to the fact that transmitter can only release a positive amount of concentration of a specific molecule into the medium. Previous works have proposed use of chemical reactions to remove molecules from the environment, and to effectively simulate negative signals. However, the differential equation describing a diffusion-reaction process is non-linear. This precludes the possibility of using Fourier transform tools. In this paper, a solution for simulating negative signals based on the diffusion-reaction channel model is proposed. While the proposed solution does not exploit the full degrees of freedom available for signaling in a diffusionreaction process, but its end-to-end system is a linear channel and amenable to Fourier transform analysis. Based on our solution, a modulation scheme and a precoder are introduced and shown to have a significant reduction in error probability compared to previous modulation schemes such as CSK, Pre-equalization, DMoSK, and MCSK. The effects of various imperfections (such as quantization error) on the communication system performance are studied.

In this paper, we consider abnormality detection via diffusive molecular communications (MCs) for a network consisting of several sensors and a fusion center (FC). If a sensor detects an abnormality, it injects a number of molecules into the medium which is proportional to its sensing output. Two transmission schemes for releasing molecules into the medium are considered. In the first scheme, each sensor releases a different type of molecule (DTM), whereas in the second scheme, all sensors release the same type of molecule (STM). The molecules released by the sensors propagate through the MC channel and some may reach the FC where the final decision regarding whether or not an abnormality has occurred is made. We derive the optimal decision rules for both DTM and STM. However, the optimal detectors entail high computational complexity as log-likelihood ratios (LLRs) have to be computed. To overcome this issue, we show that the optimal decision rule for STM can be transformed into an equivalent low-complexity decision rule. Since a similar transformation is not possible for DTM, we propose simple low-complexity sub-optimal detectors based on different approximations of the LLR. The proposed low-complexity detectors are more suitable for practical MC systems than the original complex optimal decision rule, particularly when the FC is a nano-machine with limited computational capabilities. Furthermore, we analyze the performance of the proposed detectors in terms of their false alarm and missed detection probabilities. Simulation results verify our analytical derivations and reveal interesting insights regarding the tradeoff between complexity and performance of the proposed detectors and the considered DTM and STM schemes.

Drawing on the notion of parallel interference cancellation, this paper formulates a one-shot linear receiver for the uplink of centralized, possibly cloud-based, radio access networks (C-RANs) operating in a cell-free fashion. This receiver exhibits substantial interference rejection abilities, yet it does not involve any matrix inversions; rather, its structure hinges on the pairwise projections of the users’ channel vectors. Its performance is markedly superior to that of matched-filter beamforming, while the computational cost is decidedly inferior to that of an MMSE filter, altogether constituting an attractive alternative in terms of performance vs cost. Furthermore, with a proper sparsification of the channel matrix that it estimates and processes, the proposed receiver can be rendered scalable in the sense of its computational cost per access point not growing with size of the network. Uplink power control is also readily accommodated.

This article presents a novel deep linear and nonlinear compensation network (DLNCN) that effectively addresses linear and nonlinear distortion in conjunction with polarization-dependent loss (PDL), while also accounting for changes caused by the joint impact of PDL and time-varying rotation of the state of polarization (RSOP). To accomplish this, we introduce neural network layers dedicated for PDL compensation, and we devise a transfer learning approach that selectively updates weights in layers affected by the variations while keeping the remaining weights unchanged. To monitor RSOP with PDL, we employ a pilot-based acquisition and a pilot-aided decision-directed tracking technique. Our numerical tests demonstrate successful RSOP tracking in the presence of PDL impairments, outperforming state-of-the-art schemes by an average of over 0.75 dB in Q-factor for a dual-polarized 960 km 32 Gbaud 64-QAM transmission with a polarization linewidth of 3 kHz. These results highlight the effectiveness of our proposed deep neural network structure, which includes a dedicated layer for PDL compensation, and its ability to work seamlessly with RSOP tracking.