In this paper, we propose using mobile nanosensors (MNSs) for early stage anomaly detection. For concreteness, we focus on the detection of cancer cells located in a particular region of a blood vessel. These cancer cells produce and emit special molecules, so-called biomarkers, which are symptomatic for the presence of anomaly, into the cardiovascular system. Detection of cancer biomarkers with conventional blood tests is difficult in the early stages of a cancer due to the very low concentration of the biomarkers in the samples taken. However, close to the cancer cells, the concentration of the cancer biomarkers is high. Hence, detection is possible if a sensor with the ability to detect these biomarkers is placed in the vicinity of the cancer cells. Therefore, in this paper, we study the use of MNSs that are injected at a suitable injection site and can move through the blood vessels of the cardiovascular system, which potentially contain cancer cells. These MNSs can be activated by the biomarkers close to the cancer cells, where the biomarker concentration is sufficiently high. Eventually, the MNSs are collected by a fusion center (FC) where their activation levels are read and exploited to declare the presence of anomaly. We analytically derive the biomarker concentration in a network of interconnected blood vessels as well as the probability mass function of the MNSs’ activation levels and validate the obtained results via particle-based simulations. Then, we derive the optimal decision rule for the FC regarding the presence of anomaly assuming that the entire network is known at the FC. Finally, for the FC, we propose a simple sum detector that does not require knowledge of the network topology. Our simulations reveal that while the optimal detector achieves a higher performance than the sum detector, both proposed detectors significantly outperform a benchmark scheme that uses fixed nanosensors at the FC.

This paper develops a stochastic geometry-based approach for the modeling and analysis of single-and multi-cluster wireless networks. We first define finite homogeneous Poisson point processes to model the number and locations of the transmitters in a confined region as a single-cluster wireless network. We study the coverage probability for a reference receiver for two strategies; closest-selection, where the receiver is served by the closest transmitter among all transmitters, and uniform-selection, where the serving transmitter is selected randomly with uniform distribution. Second, using Matern cluster processes, we extend our model and analysis to multi-cluster wireless networks. Here, two types of receivers are modeled, namely closed-and open-access receivers. Closed-access receivers are distributed around the cluster centers of the transmitters according to a symmetric normal distribution and can be served only by the transmitters of their corresponding clusters. Open-access receivers, on the other hand, are placed independently of the transmitters and can be served by all transmitters. In all cases, the link distance distribution and the Laplace transform (LT) of the interference are derived. We also derive closed-form lower bounds on the LT of the interference for single-cluster wireless networks. The impact of different parameters on the performance is also investigated.

In this paper, we study the degrees of freedom (DoF) region and sum DoF of the time-selective $K$ -user interference channel in the presence of intelligent reflecting surfaces (IRSs). We consider both active and passive IRSs. While both types of IRS can attenuate the amplitude and change the phase of a reflected electromagnetic wave, active IRSs are also capable of amplifying the wave. We derive inner and outer bounds for the DoF region and lower and upper bounds for the sum DoF of the $K$ -user interference channel in the presence of an active IRS and prove that the maximum value of $K$ for the sum DoF can be achieved if the number of IRS elements exceeds a certain finite value. The analysis framework developed for active IRSs forms the basis for our analysis of passive IRS-assisted systems. In particular, we present probabilistic inner and outer bounds for the DoF region and probabilistic lower and upper bounds for the sum DoF of the $K$ -user interference channel in the presence of a passive IRS and prove that the lower bound for the sum DoF asymptotically approaches $K$ as the number of IRS elements grows large.

While ISI is a common issue in classical communications, it is more challenging and prominent in the context of molecular communication because one cannot readily combat ISI with classical channel equalization techniques. This is due to the fact that transmitter can only release a positive amount of concentration of a specific molecule into the medium. Previous works have proposed use of chemical reactions to remove molecules from the environment, and to effectively simulate negative signals. However, the differential equation describing a diffusion-reaction process is non-linear. This precludes the possibility of using Fourier transform tools. In this paper, a solution for simulating negative signals based on the diffusion-reaction channel model is proposed. While the proposed solution does not exploit the full degrees of freedom available for signaling in a diffusionreaction process, but its end-to-end system is a linear channel and amenable to Fourier transform analysis. Based on our solution, a modulation scheme and a precoder are introduced and shown to have a significant reduction in error probability compared to previous modulation schemes such as CSK, Pre-equalization, DMoSK, and MCSK. The effects of various imperfections (such as quantization error) on the communication system performance are studied.

In this paper, we consider abnormality detection via diffusive molecular communications (MCs) for a network consisting of several sensors and a fusion center (FC). If a sensor detects an abnormality, it injects a number of molecules into the medium which is proportional to its sensing output. Two transmission schemes for releasing molecules into the medium are considered. In the first scheme, each sensor releases a different type of molecule (DTM), whereas in the second scheme, all sensors release the same type of molecule (STM). The molecules released by the sensors propagate through the MC channel and some may reach the FC where the final decision regarding whether or not an abnormality has occurred is made. We derive the optimal decision rules for both DTM and STM. However, the optimal detectors entail high computational complexity as log-likelihood ratios (LLRs) have to be computed. To overcome this issue, we show that the optimal decision rule for STM can be transformed into an equivalent low-complexity decision rule. Since a similar transformation is not possible for DTM, we propose simple low-complexity sub-optimal detectors based on different approximations of the LLR. The proposed low-complexity detectors are more suitable for practical MC systems than the original complex optimal decision rule, particularly when the FC is a nano-machine with limited computational capabilities. Furthermore, we analyze the performance of the proposed detectors in terms of their false alarm and missed detection probabilities. Simulation results verify our analytical derivations and reveal interesting insights regarding the tradeoff between complexity and performance of the proposed detectors and the considered DTM and STM schemes.