Accurate estimation of forest aboveground biomass (AGB) and understanding its ecological drivers are vital for carbon monitoring and sustainable forest management. However, AGB estimation using remote sensing is hindered by signal saturation in high-biomass areas and insufficient attention to ecological structural factors. Focusing on Guangdong Province, this study proposes a novel approach that spatially extrapolates airborne LiDAR-derived Forest structural parameters and integrates them with Sentinel-1/2 data to construct an AGB prediction model. Results show that incorporating structural parameters significantly reduces saturation effects, improving prediction accuracy and AGB maximum range in high-AGB regions (R² from 0.724 to 0.811; RMSE = 10.64 Mg/ha; max AGB > 180 Mg/ha). Using multi-scale geographically weighted regression (MGWR), we further examined the spatial influence of forest type, age structure, and species mixture. Forest age showed a strong positive correlation with AGB in over 95% of the area, particularly in mountainous and hilly regions (coefficients up to 1.23). Species mixture had positive effects in 87.7% of the region, especially in the north and parts of the south. Natural forests consistently exhibited higher AGB than plantations, with differences amplifying at later successional stages. Highly mixed natural forests showed faster biomass accumulation and higher steady-state AGB, highlighting the regulatory role of structural complexity and successional maturity. This study not only mitigates remote sensing saturation issues but also deepens understanding of spatial and ecological drivers of AGB, offering theoretical and technical support for targeted carbon stock assessment and forest management strategies.