The aim of this work was to assess the numerous approaches to structural and material modeling of brain tissue under dynamic loading conditions. The current technological improvements in material modeling have led to various approaches described in the literature. However, the methods used for the determination of the brain’s characteristics have not always been stated or clearly defined and material data are even more scattered. Thus, the research described in this paper explicitly underlines directions for the development of numerical brain models. An important element of this research is the development of a numerical model of the brain based on medical imaging methods. This approach allowed the authors to assess the changes in the mechanical and geometrical parameters of brain tissue caused by the impact of mechanical loads. The developed model was verified through comparison with experimental studies on post-mortem human subjects described in the literature, as well as through numerical tests. Based on the current research, the authors identified important aspects of the modeling of brain tissue that influence the assessment of the actual biomechanical response of the brain for dynamic analyses.

Traumatic brain injury (TBI) is a major public health problem among children. The predominant causes of TBI in young children are motor vehicle accidents, firearm incidents, falls, and child abuse. The limitation of in vivo studies on the human brain has made the finite element modelling an important tool to study brain injury. Numerical models based on the finite element approach can provide valuable data on biomechanics of brain tissues and help explain many pathological conditions. This work reviews the existing numerical models of a child’s head. However, the existing literature is very limited in reporting proper geometric representation of a small child’s head. Therefore, an advanced 2-year-old child’s head model, named aHEAD 2yo (aHEAD: advanced Head models for safety Enhancement And medical Development), has been developed, which advances the state-of-the-art. The model is one of the first published in the literature, which entirely consists of hexahedral elements for three-dimensional (3D) structures of the head, such as the cerebellum, skull, and cerebrum with detailed geometry of gyri and sulci. It includes cerebrospinal fluid as Smoothed Particle Hydrodynamics (SPH) and a detailed model of pressurized bringing veins. Moreover, the presented review of the literature showed that material models for children are now one of the major limitations. There is also no unambiguous opinion as to the use of separate materials for gray and white matter. Thus, this work examines the impact of various material models for the brain on the biomechanical response of the brain tissues during the mechanical loading described by Hardy et al. The study compares the inhomogeneous models with the separation of gray and white matter against the homogeneous models, i.e., without the gray/white matter separation. The developed model along with its verification aims to establish a further benchmark in finite element head modelling for children and can potentially provide new insights into injury mechanisms.

Brain damage is a serious economic and social burden. Contact sports such as American football, are one of the most common sources of concussions. The biomechanical response of the head–helmet system caused by dynamic loading plays a major role. The literature has focused on measuring the resultant kinematics that act on the head and helmet during tackles. However, few studies have focused on helmet validation tests, supported by recent findings and emerging numerical approaches. The future of helmet standards could benefit from insights at the level of injury mechanisms, using numerical tools to assess the helmets. Therefore, in this work, a numerical approach is employed to investigate the influence of intracranial pressure (ICP) on brain pathophysiology during and after helmeted impacts, which are common in American football. The helmeted impacts were performed at several impact locations according to the NOCSAE standard (configurations A, AP, B, C, D, F, R, UT). In order to evaluate the ICP levels, the αHEAD finite element head and brain model was combined with a Hybrid III-neck structure and then coupled with an American football helmet to simulate the NOCSAE impacts. In addition, the ICP level was analyzed together with the resulting HIC value, since the latter is commonly used, in this application and others, as the injury criterion. The obtained results indicate that ICP values exceed the common threshold of head injury criteria and do not correlate with HIC values. Thus, this work raises concern about applying the HIC to predict brain injury in American football direct head impacts, since it does not correlate with ICP predicted with the FE head model.

The human head is a highly complex structure, with a combination of hard and soft tissues and a variety of materials and interactions. Many researchers have used computational approaches to model the head, and several human finite element head models can be found in the literature. However, most of them are not geometrically accurate – for instance, the brain is simplified to a smooth spherical volume, which poses some concerns regarding boundary conditions and geometrical accuracy. Therefore, an advanced head model of a 28-year-old, designated as aHEAD 28 yo (aHEAD: advanced Head models for safety Enhancement And medical Development), has been developed. The model consists entirely of hexahedral elements for 3D structures of the head such as the cerebellum, skull and cerebrum, with detailed geometry of the gyri and sulci. Additionally, it is one of the first human head approaches published in the literature that includes cerebrospinal fluid simulated by Smoothed Particle Hydrodynamics (SPH) and a detailed model of pressurized bridging veins. To support the model’s credibility, this study is focused on physical material testing. A novel comprehensive experimental-computational approach is presented, which involves the brain tissue’s response to induced vibrations. The experiment successfully aimed to validate the material models used in the numerical analysis. Additionally, the authors present a kinematical model validation based on the Hardy experimental cadaver test. The developed model, along with its verification, aims to establish a further benchmark in finite element head modelling and can potentially provide new insights into injury mechanisms.