The COVID-19 pandemic has affected many aspects of human life around the world, due to its tremendous outcomes on public health and socio-economic activities. Policy makers have tried to develop efficient responses based on technologies and advanced pandemic control methodologies, to limit the wide spreading of the virus in urban areas. However, techniques such as social isolation and lockdown are short-term solutions that minimize the spread of the pandemic in cities and do not invert long-term issues that derive from climate change, air pollution and urban planning challenges that enhance the spreading ability. Thus, it seems crucial to understand what kind of factors assist or prevent the wide spreading of the virus. Although AI frameworks have a very efficient predictive ability as data-driven procedures, they often struggle to identify strong correlations among multidimensional data and provide robust explanations. In this paper, we propose the fusion of a heterogeneous, spatio-temporal dataset that combine data from eight European cities spanning from 1 January 2020 to 31 December 2021 and describe atmospheric, socio-economic, health, mobility and environmental factors all related to potential links with COVID-19. Remote sensing data are the key solution to monitor the availability on public green spaces between cities in the study period. So, we evaluate the benefits of NIR and RED bands of satellite images to calculate the NDVI and locate the percentage in vegetation cover on each city for each week of our 2-year study. This novel dataset is evaluated by a tree-based machine learning algorithm that utilizes ensemble learning and is trained to make robust predictions on daily cases and deaths. Comparisons with other machine learning techniques justify its robustness on the regression metrics RMSE and MAE. Furthermore, the explainable frameworks SHAP and LIME are utilized to locate potential positive or negative influence of the factors on global and local level, with respect to our model’s predictive ability. A variation of SHAP, namely treeSHAP, is utilized for our tree-based algorithm to make fast and accurate explanations.
1 January 2025 in Computational and Structural Biotechnology Journal
Federated Learning has been rapidly gaining in popularity in medical applications, due to the increased privacy offered, since medical data doesn't need to leave the hospitals' premises for AI model training. However, a direct translation of a classic experiment to a federated one is not always straightforward. In this work, we delve into the intricacies of federated learning for a breast cancer classification tool. We compare classic model training with a federated variant, and highlight the adaptations that need to be taken care of to ensure the equivalence between the two. Specifically, we introduce the Breast Area Detection tool as an essential component of the pre-processing pipeline to enhance the robustness of Federated Learning by offering data harmonization. On top of that, we present an end-to-end Federated Learning framework that is effective for real-world data and scenarios. Among the three real-world hospitals involved in the experimental procedure, the proposed framework significantly improves performance at the first hospital, providing consistent results similar to those achieved in the classic approach. Experimental results demonstrate that the interventions introduced improved model performance by approximately 35%, aligning federated learning and centralized model performance.
In this study, we propose a tensor-based learning model to efficiently detect abnormalities on digital mammograms. Due to the fact that the availability of medical data is limited and often restricted by GDPR (general data protection regulation) compliance, the need for more sophisticated and less data-hungry approaches is urgent. Accordingly, our proposed artificial intelligence framework utilizes the canonical polyadic decomposition to decrease the trainable parameters of the wrapped Rank-R FNN model, leading to efficient learning using small amounts of data. Our model was evaluated on the open source digital mammographic database INBreast and compared with state-of-the-art models in this domain. The experimental results show that the proposed solution performs well in comparison with the other deep learning models, such as AlexNet and SqueezeNet, achieving 90% ± 4% accuracy and an F1 score of 84% ± 5%. Additionally, our framework tends to attain more robust performance with small numbers of data and is computationally lighter for inference purposes, due to the small number of trainable parameters.
In this work, we present an integrated framework for classifying digital or digitized mammograms according to either BIRADS scale or breast density score. We propose unified data preparation procedure, a common training process that includes a Convolutional Neural Network approach and a simple inference tool aiming to ensure the robustness of out model and provide a more generalized solution. We utilize not only a private dataset for training and validation, but also the open dataset INBreast for the testing procedure. According to our results, our solution achieves; a) accuracy score 87% and F1 score 82% on Density classification, and b) accuracy score 85% and F1 score 80% on BIRADS classification.