The genus Croton (Euphorbiaceae) encompasses numerous species recognized for their diverse medicinal applications, particularly in pain management. This systematic review aims to compile and analyze the scientific evidence on the antinociceptive properties of Croton species. The review protocol was registered in the Open Science Framework (OSF) associated project: osf.io/z4juf. Using the PRISMA methodology, an exhaustive search was conducted in databases such as PubMed, Scopus, and Web of Science to identify relevant studies published to date. The review includes preclinical studies in animal models that investigate the mechanisms of action and efficacy of Croton extracts and isolated compounds in pain inhibition. The results indicate that 28 Croton species exhibit significant antinociceptive effects, attributed to bioactive compounds such as diterpenes, alkaloids, and flavonoids. These compounds interact with multiple biological pathways, including ion channels, such as TRPV1, K/ATP, and ASIC channels, as well as the inhibition of the synthesis of inflammatory mediators, particularly prostaglandins. This review highlights the potential of Croton as a source of novel analgesic agents and emphasizes the necessity for further clinical studies. Additionally, integrating ethnobotanical and pharmacological knowledge is suggested to develop innovative and effective treatments for pain management.

Chronic diseases such as type 2 diabetes mellitus (T2DM), arterial hypertension (HTN), and obesity are significant global health challenges, contributing to millions of premature deaths. In Mexico, these pose major challenges due to limited access to healthcare and inadequate primary care quality. Complementary medicine presents itself as an adjuvant in this context, offering minimally invasive techniques to enhance physical, mental, and spiritual well-being. However, effective treatment adherence is crucial for positive outcomes, influenced by self-efficacy, resulting in persistently low adherence rates—a pressing public health concern. This observational study aimed to explore how perceptions of complementary medicine and treatment adherence predict self-efficacy among individuals with chronic diseases in Mexico. Data were collected from 113 participants with chronic conditions, including T2DM, HTN, and obesity. Participants completed surveys assessing perception of complementary medicine, treatment adherence, and self-efficacy. Statistical analyses, including correlations and regression, were conducted to examine the relationships between variables. The study revealed significant correlations between the perception of complementary medicine, treatment adherence, and self-efficacy. Treatment adherence was positively associated with self-efficacy, while perception of holistic medicine was negatively correlated with self-efficacy. Perception of complementary medicine and adherence to treatment were found to predict 41.9% (p = 0.001) self-efficacy. These findings underscore the potential of complementary therapies in enhancing self-efficacy levels, and highlight the importance of holistic healthcare approaches in managing chronic conditions. Further research is needed to better understand these relationships and their implications for healthcare outcomes in Mexico and beyond.

El estudio de los conocimientos sobre diabetes en estudiantes de enfermería es crucial para evaluar y mejorar la formación en esta área crítica de la salud. Utilizando un modelo estructural predictor, se puede analizar cómo estos conocimientos influyen en la agencia de autocuidado de los estudiantes. El objetivo fue determinar el efecto de los conocimientos de la diabetes sobre la agencia de autocuidado en estudiantes de enfermería. Estudio de diseño correlacional-explicativo, muestreo no probabilístico a conveniência, N= 246 estudiantes de enfermería. Se colectaron datos sociodemográficos, se aplicó el Cuestionario “Diabetes Knowledge Questionnaire” (DKQ-24) (α=.78) y la Escala de Agencia de Autocuidado (ASA) (α=.77). Se realizó estadística descriptiva e inferencial mediante prueba de Pearson y un modelo de ecuación estructural. Se consideraron aspectos éticos. Media de edad 20.45±2.5 años, 28% hombres y 72% mujeres. En los conocimientos sobre diabetes 51.2% poseen conocimientos adecuados y en promedio 94.01±13.59 posee agencia de autocuidado. Se halló correlación entre los conocimientos en diabetes y la agencia de autocuidado (r=0.256, p<0.001), aunado que el conocimiento de la diabetes en los enfermeros afecta positivamente la capacidad de agencia de autocuidado en estudiantes enfermeros (λ = .31). Los conocimientos sobre diabetes mejoran la agencia de autocuidado en estudiantes de enfermería. Es esencial una educación profunda en diabetes y programas universitarios de atención primaria para apoyar su autocuidado y prevenir futuras enfermedades crónicas.

La seguridad del paciente implica acciones cuyo objetivo principal es mitigar riesgos y prevenir daños evitables con disminución de errores en la población bajo atención sanitaria. La capacitación de profesionales de la salud es fundamental y constituye un pilar esencial para transformar la prestación de servicios médicos. El objetivo del presente artículo es realizar un análisis factorial confirmatorio del “Cuestionario para medir actitudes y conocimientos de seguridad del paciente”, aplicado en estudiantes de enfermería y medicina de la Universidad Autónoma del Estado de Quintana Roo. Se utilizó una muestra de 220 estudiantes de medicina y enfermería en el último ciclo de formación de pregrado, pertenecientes a la División de Ciencias de la Salud. El instrumento fue autoadministrado, anónimo y bajo consentimiento informado. La población tuvo una edad promedio de 22 años (DE=2 años) se realizó Análisis Factorial Exploratorio (AFE) por máxima verosimilitud y rotación Varimax y Análisis Factorial Confirmatorio (AFC) para probar la validez de la escala con el Índice de Ajuste Comparativo (CFI), Bentler-Bonett de Ajuste Normado (BBNFI) y No-Normado (BBNNFI), Error de Aproximación Cuadrático Medio (RMSEA). Esta investigación aporta un instrumento válido y confiable para la medición de actitudes y conocimientos sobre seguridad del paciente en estudiantes mexicanos de medicina y enfermería, considerando las particularidades de la muestra con 21 ítems, distribuidos en 5 factores: apertura en comunicación, actitud proactiva para evitar riesgos en los procesos, conciencia del error, comprensión del factor humano y, por último, complejidad e interrelación del sistema.

Background: In recent decades, noise pollution has become a significant concern, especially in sensitive environments such as hospitals. For neonates in neonatal intensive care units (NICUs), noise can have serious implications due to their underdeveloped auditory and physiological systems. Elevated noise levels in NICUs have been linked to disruptions in normal physiological parameters and can negatively impact both neonatal health and staff performance. Aim: To identify and quantify sources of noise in the intensive care unit of a hospital NICU. Methods: An observational study was conducted to assess noise levels in a Mexican NICU. Noise measurements were taken across 22 different scenarios identified as potential noise sources, during all three shifts to capture variations throughout the day. Results: Noise levels ranged from 45 to 70 decibels (dB). The nursing shift change was identified as the scenario with the highest noise level, while the paper dispenser area recorded the lowest. These findings highlight specific times and locations within the NICU where noise reduction interventions should be focused. Conclusions: Targeted noise control strategies, especially during shift changes, could significantly improve the acoustic environment in NICUs, helping to safeguard neonatal well‐being and staff performance.

Chronic conditions like type 2 diabetes mellitus (T2DM), arterial hypertension (HTN), and obesity are major global health issues, causing significant morbidity and mortality. In Latin America, these conditions contribute to millions of premature deaths annually, posing challenges exacerbated by limited healthcare access and poor primary care quality, particularly in Mexico. Complementary medicine presents a potential solution, offering minimally invasive techniques to improve physical, mental, and spiritual well-being. Effective treatment adherence, crucial for positive outcomes, is influenced by self-efficacy, the ability to manage one's behavior in response to medical conditions. However, treatment adherence rates remain low, indicating a pressing public health concern. This study aimed to explore how perception of complementary medicine and treatment adherence predict self-efficacy among individuals with chronic conditions in Mexico. Analyzing data from 113 participants revealed significant correlations between variables, with treatment adherence positively associated with self-efficacy and perception of holistic medicine negatively correlated with self-efficacy. Regression analysis showed that incorporating perception of complementary medicine and treatment adherence significantly explained self-efficacy levels, suggesting the potential of complementary therapies in holistic healthcare approaches. However, collinearity between variables highlights the need for further research to better understand these relationships and their implications for improving healthcare outcomes in Mexico. Integrating complementary therapies with conventional treatments could enhance overall well-being and treatment adherence, offering promising avenues for addressing chronic conditions in the region. These findings underscore the importance of comprehensive healthcare approaches that integrate both conventional and complementary modalities to optimize health outcomes and quality of life for individuals with chronic conditions in Mexico and beyond.