Ludovica Rosa Maria Lanzafame

Dr. Ludovica Rosa Maria Lanzafame

Azienda Ospedaliera Universitaria Policlinico "G. Martino", Messina, Sicilia, Italy
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 February 2023 in Life
Verified
Journal Article
Open access
LLLudovica Rosa Maria Lanzafame
Ludovica Rosa Maria Lanzafame
GBGiuseppe Mauro Bucolo
Giuseppe Mauro Bucolo
GMGiuseppe Muscogiuri
Giuseppe Muscogiuri
SSSandro Sironi
Sandro Sironi
MGMichele Gaeta
Michele Gaeta
TDTommaso D'Angelo
Tommaso D'Angelo
The technological development of Artificial Intelligence (AI) has grown rapidly in recent years. The applications of AI to cardiovascular imaging are various and could improve the radiologists’ workflow, speeding up acquisition and post-processing time, increasing image quality and diagnostic accuracy. Several studies have already proved AI applications in Coronary Computed Tomography Angiography and Cardiac Magnetic Resonance, including automatic evaluation of calcium score, quantification of coronary stenosis and plaque analysis, or the automatic quantification of heart volumes and myocardial tissue characterization. The aim of this review is to summarize the latest advances in the field of AI applied to cardiovascular CT and MR imaging.

14 August 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
TDTommaso D'Angelo
Tommaso D'Angelo
LLLudovica Rosa Maria Lanzafame
Ludovica Rosa Maria Lanzafame
AMAntonino Micari
Antonino Micari
ABAlfredo Blandino
Alfredo Blandino
IYIbrahim Yel
Ibrahim Yel
SMSilvio Mazziotti
Silvio Mazziotti
Background: To evaluate if coronary CT angiography (CCTA) monoenergetic reconstructions, obtained with a dual-layer spectral detector computed tomography (DLCT) system, offer improved image quality compared with 120 kVp conventional images without affecting the quantitative assessment of coronary stenoses. Methods: Fifty CCTA datasets (30 men; mean age: 61.6 ± 12.3 years) acquired with a DLCT system were reconstructed using virtual monoenergetic images (VMI) from 40 to 100 keV with 10 keV increment and compared with conventional images. An analysis of objective image quality was performed, evaluating the signal- and contrast-to-noise ratio. For the subjective assessment, two readers used a 5-point Likert scoring system to evaluate sharpness, noise, demarcation of coronary plaques, vascular contrast, and an overall score. Furthermore, coronary stenoses were analyzed for each vessel to describe the diagnostic agreement between monoenergetic images and conventional images. Results: The objective image analysis showed that all reconstructions from 70 keV to 40 keV show higher SNR (from 61.33 ± 12.46 to 154.22 ± 42.91, respectively) and CNR (from 51.45 ± 11.19 to 135.63 ± 39.38, respectively) compared with conventional images (all p < 0.001). The 40 keV monoenergetic images obtained the best average score for sharpness, vascular contrast, and for the overall impression (all with p < 0.001). The detection and grading of stenoses of the coronary arteries with conventional and monoenergetic images at 70 keV and 40 keV showed an overall excellent interobserver agreement (k= 0.81 [0.72–0.91]). Conclusions: The 40 keV virtual monoenergetic images obtained with a DLCT system allow the objective and subjective image quality of coronary CT angiography to be improved.

26 June 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
LLLudovica Rosa Maria Lanzafame
Ludovica Rosa Maria Lanzafame
CGClaudia Gulli
Claudia Gulli
SMSilvio Mazziotti
Silvio Mazziotti
GAGiorgio Ascenti
Giorgio Ascenti
MGMichele Gaeta
Michele Gaeta
TDTommaso D'Angelo
Tommaso D'Angelo
Artificial intelligence (AI) is reshaping radiological practice, with recent advancements in natural language processing (NLP), large language models (LLMs), and chatbot technologies opening new avenues for clinical integration. These AI-driven conversational agents have demonstrated potential in streamlining patient triage, optimizing imaging protocol selection, supporting image interpretation, automating radiology report generation, and improving communication among radiologists, referring physicians, and patients. Emerging evidence also highlights their role in decision-making, clinical data extraction, and structured reporting. While the clinical adoption of chatbots remains limited by concerns related to data privacy, model robustness, and ethical oversight, ongoing developments and regulatory efforts are paving the way for responsible implementation. This review provides a critical overview of the current and emerging applications of chatbots in radiology, evaluating their capabilities, limitations, and future directions for clinical and research integration.

16 November 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
LLLudovica Rosa Maria Lanzafame
Ludovica Rosa Maria Lanzafame
MCMaria Ludovica Carerj
Maria Ludovica Carerj
GRGiovanna Rizzo
Giovanna Rizzo
FMFabio Minutoli
Fabio Minutoli
GBGiuseppe Mauro Bucolo
Giuseppe Mauro Bucolo
TDTommaso D'Angelo
Tommaso D'Angelo
Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibro-inflammatory disorder. Coronary IgG4-RD has been scarcely reported and may present as “tumor-like” lesions. These pseudo-masses may be underdiagnosed mainly due to a vague clinical picture that can vary from complete lack of symptoms to acute coronary syndrome or sudden cardiac death. Early recognition of coronary IgG4-RD is essential to monitor disease activity and prevent life-threatening complications. We report a comprehensive non-invasive imaging evaluation of a patient affected by coronary IgG4-RD, which was diagnosed as an incidental finding during routine pre-laparoscopic cholecystectomy checkup. Non-invasive imaging revealed the presence of a peri-coronary soft-tissue mass that was stable at 12 months follow-up.

29 September 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
LLLudovica Rosa Maria Lanzafame
Ludovica Rosa Maria Lanzafame
ABAlfredo Blandino
Alfredo Blandino
GCGiuseppe Cicero
Giuseppe Cicero
Placido RomeoPlacido Romeo
Placido Romeo
SASalvatore Agati
Salvatore Agati
TDTommaso D'Angelo
Tommaso D'Angelo
Button battery ingestion (BBI) is common in children and its prevalence has increased in the last decades. BBI can be responsible for very severe and potentially fatal complications if not promptly detected. We describe the successful management of two cases of BBI that occurred in two previously healthy infants. Both patients presented with vague symptoms and no witness of foreign body ingestion. The prolonged time of exposure to the corrosive effects of disk batteries was responsible for the development of tracheo-esophageal fistula (TEF) and aorto-esophageal fistula (AEF). We demonstrate how prompt diagnosis and management are crucial for the infants’ survival.

1 December 2024 in Radiology: Cardiothoracic Imaging
Verified
Journal Article
Closed access
APAnna Palmisano
Anna Palmisano
EBElisa Bruno
Elisa Bruno
GAGiovanni Donato Aquaro
Giovanni Donato Aquaro
CGCarmelo De Gori
Carmelo De Gori
SBSimone Barbieri
Simone Barbieri
AEAntonio Esposito
Antonio Esposito
Mitral annular disjunction (MAD) was a frequent incidental finding at cardiac MRI examinations performed for various clinical indications; longer MAD length and coexisting bileaflet mitral valve prolapse were associated with a higher prevalence of arrhythmia.