The development of artificial intelligence (AI) has revolutionized medical care in recent years and plays a vital role in a number of areas, such as diagnostics and forecasting. In this review, we discuss the most promising areas of AI application to the field of bone tissue engineering and prosthetics, which can drastically benefit from AI-assisted optimization and patient personalization of implants and scaffolds in ways ranging from visualization and real-time monitoring to the implantation cases prediction, thereby leveraging the compromise between specific architecture decisions, material choice, and synthesis procedure. With the emphasized crucial role of accuracy and robustness of developed AI algorithms, especially in bone tissue engineering, it was shown that rigorous validation and testing, demanding large datasets and extensive clinical trials, are essential, and we discuss how through developing multidisciplinary cooperation among biology, chemistry with materials science, and AI, these challenges can be addressed.
The role of machine learning (a part of artificial intelligence—AI) in the diagnosis and treatment of various types of oncology is steadily increasing. It is expected that the use of AI in oncology will speed up both diagnostic and treatment planning processes. This review describes recent applications of machine learning in oncology, including medical image analysis, treatment planning, patient survival prognosis, and the synthesis of drugs at the point of care. The fast and reliable analysis of medical images is of great importance in the case of fast-flowing forms of cancer. The introduction of ML for the analysis of constantly growing volumes of big data makes it possible to improve the quality of prescribed treatment and patient care. Thus, ML is expected to become an essential technology for medical specialists. The ML model has already improved prognostic prediction for patients compared to traditional staging algorithms. The direct synthesis of the necessary medical substances (small molecule mixtures) at the point of care could also seriously benefit from the application of ML. We further review the main trends in the use of artificial intelligence-based technologies in modern oncology. This review demonstrates the future prospects of using ML tools to make progress in cancer research, as well as in other areas of medicine. Despite growing interest in the use of modern computer technologies in medical practice, a number of unresolved ethical and legal problems remain. In this review, we also discuss the most relevant issues among them.
16 April 2020 in Advanced Engineering Research (Rostov-on-Don)