Coffee is a crop of great relevance in socioeconomic terms for Brazilian agribusiness, which is the world’s largest producer in cultivated areas. The implementation of precision agriculture in the coffee culture has provided countless benefits to its development, which over the years has been cultivated in the same area. However, there is a lack of studies that address the impact of the application of variable-rates inputs in soil on the energy efficiency and sustainability of these systems. This study aimed to analyze how variable-rate fertilization influences energy efficiency in coffee growing. A production area subjected to variable and fixed rates of fertilizer in alternating rows was evaluated. Geo-referenced yield data was collected to assess yield response for fixed and variable rate applications. The energy assessment was combined with the Geographic Information System (GIS) to determine site-specific energy indicators. To determine the energy flow, only NPK fertilizer applications were considered as inputs and the yield as output. The results obtained indicated that the variable rate fertilizer application has a small difference, indicating greater energy efficiency concerning the applied fertilizer and coffee production per crop season. It was observed in the 06/07 crop, the incorporated energy was 10.7 MJ kg⁻¹ for VR and 10.2 MJ kg⁻¹ for UR and for the 07/08 crop it was 30.7 MJ kg⁻¹ for VR and 34.9 MJ kg⁻¹ for UR. The energy balance was more efficient at variable rates, as it provided fertilizer savings without compromising yield. However, the difference between the embodied energy per mass of coffee produced was very small compared to the fixed rate.