The Machine Learning/Deep Learning (ML/DL) forecasting model has helped stakeholders overcome uncertainties associated with renewable energy resources and time planning for probable near-term power fluctuations. Nevertheless, the effectiveness of long-term forecasting of renewable energy resources using an existing ML/DL model is still debatable and needs additional research. Considering the constraints inherent in current empirical or physical-based forecasting models, the study utilizes ML/DL models to provide long-term predictions for solar power production. This study aims to examine the efficacy of several existing forecasting models. The study suggests approaches to enhance the accuracy of long-term forecasting of solar power generation for a case study power plant. It summarizes and compares the statistical model (ARIMA), ML model (SVR), DL models (LSTM, GRU, etc.), and ensemble models (RF, hybrid) with respect to long-term prediction. The performances of the univariate and multivariate models are summarized and compared based on their ability to accurately predict solar power generation for the next 1, 3, 5, and 15 days for a 100-kW solar power plant in Lubbock, TX, USA. Conclusions are drawn predicting the accuracy of various model changes with variation in the prediction time frame and input variables. In summary, the Random Forest model predicted long-term solar power generation with 50% better accuracy over the univariate statistical model and 10% better accuracy over multivariate ML/DL models.

The study incorporates an overview of the green hydrogen-production potential from wind energy in the USA, its application in power generation and the scope of substituting grey and blue hydrogen for industrial usage. Over 10 million metric tons of grey and blue hydrogen is produced in the USA annually to fulfil the industrial demand, whereas, for 1 million metric tons of hydrogen generated, 13 million metric tons of CO₂ are released into the atmosphere. The research aims to provide a state-of-the-art review of the green hydrogen technology value chain and a case study on the production of green hydrogen from an 8-MW wind turbine installed in the southern plain region of Texas. This research estimates that the wind-farm capacity of 130 gigawatt-hours is required to substitute grey and blue hydrogen for fulfilling the current US annual industrial hydrogen demand of 10 million metric tons. The study investigates hydrogen-storage methods and the scope of green hydrogen-based storage facilities for energy produced from a wind turbine. This research focuses on the USA’s potential to meet all its industrial and other hydrogen application requirements through green hydrogen.

Detection of tumor-infiltrating lymphocytes (TILs) in cancer images has gained significant importance as these lymphocytes can be used as a biomarker in cancer detection and treatment procedures. Our goal was to develop and apply a TILs detection tool that utilizes deep learning models, following two sequential steps. First, based on the guidelines from the International Immuno-Oncology Biomarker Working Group (IIOBWG) on Breast Cancer, we labeled 63 large pathology imaging slides and annotated the TILs in the stroma area to create the dataset required for model development. In the second step, various machine learning models were employed and trained to detect the stroma where U-Net deep learning structure was able to achieve 98% accuracy. After detecting the stroma area, a Mask R-CNN model was employed for the TILs detection task. The R-CNN model detected the TILs in various images and was used as the backbone analysis network for the GUI development of the TILs detection tool. This is the first study to combine two deep learning models for TILs detection at the cellular level in breast tumor histopathology slides. Our novel approach can be applied to scoring TILs in large cancer slides. Statistical analysis showed that the output of the implemented approach had 95% concordance with the scores assigned by the pathologists, with a p-value of 0.045 (n = 63). This demonstrated that the results from the developed software were statistically meaningful and highly accurate. The implemented approach in analyzing whole tumor histology slides and the newly developed TILs detection tool can be used for research purposes in biomedical and pathology applications and it can provide researchers and clinicians with the TIL score for various input images. Future research using additional breast cancer slides from various sources for further training and validation of the developed models is necessary for more inclusive, rigorous, and robust clinical applications.

The need to deliver accurate predictions of renewable energy generation has long been recognized by stakeholders in the field and has propelled recent improvements in more precise wind speed prediction (WSP) methods. Models such as Weibull-probability-density-based WSP (WEB), Rayleigh-probability-density-based WSP (RYM), autoregressive integrated moving average (ARIMA), Kalman filter and support vector machines (SVR), artificial neural network (ANN), and hybrid models have been used for accurate prediction of wind speed with various forecast horizons. This study intends to incorporate all these methods to achieve a higher WSP accuracy as, thus far, hybrid wind speed predictions are mainly made by using multivariate time series data. To do so, an error correction algorithm for the probability-density-based wind speed prediction model is introduced. Moreover, a comparative analysis of the performance of each method for accurately predicting wind speed for each time step of short-term forecast horizons is performed. All the models studied are used to form the prediction model by optimizing the weight function for each time step of a forecast horizon for each model that contributed to forming the proposed hybrid prediction model. The National Oceanic and Atmospheric Administration (NOAA) and System Advisory Module (SAM) databases were used to demonstrate the accuracy of the proposed models and conduct a comparative analysis. The results of the study show the significant improvement on the performance of wind speed prediction models through the development of a proposed hybrid prediction model.