Due to the scarcity of observational data and the intricate precipitation–runoff relationship, individually applying physically based hydrological models and machine learning (ML) techniques presents challenges in accurately predicting floods within data-scarce glacial river basins. To address this challenge, this study introduces an innovative hybrid model that synergistically harnesses the strengths of multi-source remote sensing data, a physically based hydrological model (i.e., Spatial Processes in Hydrology (SPHY)), and ML techniques. This novel approach employs MODIS snow cover data and remote sensing-derived glacier mass balance data to calibrate the SPHY model. The SPHY model primarily generates baseflow, rain runoff, snowmelt runoff, and glacier melt runoff. These outputs are then utilized as extra inputs for the ML models, which consist of Random Forest (RF), Gradient Boosting (GDBT), Long Short-Term Memory (LSTM), Deep Neural Network (DNN), Support Vector Machine (SVM) and Transformer (TF). These ML models reconstruct the intricate relationship between inputs and streamflow. The performance of these six hybrid models and SPHY model is comprehensively explored in the Manas River basin in Central Asia. The findings underscore that the SPHY-RF model performs better in simulating and predicting daily streamflow and flood events than the SPHY model and the other five hybrid models. Compared to the SPHY model, SPHY-RF significantly reduces RMSE (55.6%) and PBIAS (62.5%) for streamflow, as well as reduces RMSE (65.8%) and PBIAS (73.51%) for floods. By utilizing bootstrap sampling, the 95% uncertainty interval for SPHY-RF is established, effectively covering 87.65% of flood events. Significantly, the SPHY-RF model substantially improves the simulation of streamflow and flood events that the SPHY model struggles to capture, indicating its potential to enhance the accuracy of flood prediction within data-scarce glacial river basins. This study offers a framework for robust flood simulation and forecasting within glacial river basins, offering opportunities to explore extreme hydrological events in a warming climate.

Accurately simulating glacier mass balance (GMB) data is crucial for assessing the impacts of climate change on glacier dynamics. Since physical models often face challenges in comprehensively accounting for factors influencing glacial melt and uncertainties in inputs, machine learning (ML) offers a viable alternative due to its robust flexibility and nonlinear fitting capability. However, the effectiveness of ML in modeling GMB data across diverse glacier types within High Mountain Asia has not yet been thoroughly explored. This study addresses this research gap by evaluating ML models used for the simulation of annual glacier-wide GMB data, with a specific focus on comparing maritime glaciers in the Niyang River basin and continental glaciers in the Manas River basin. For this purpose, meteorological predictive factors derived from monthly ERA5-Land datasets, and topographical predictive factors obtained from the Randolph Glacier Inventory, along with target GMB data rooted in geodetic mass balance observations, were employed to drive four selective ML models: the random forest model, the gradient boosting decision tree (GBDT) model, the deep neural network model, and the ordinary least-square linear regression model. The results highlighted that ML models generally exhibit superior performance in the simulation of GMB data for continental glaciers compared to maritime ones. Moreover, among the four ML models, the GBDT model was found to consistently exhibit superior performance with coefficient of determination ($R^2$) values of 0.72 and 0.67 and root mean squared error ($RMSE$) values of 0.21 m w.e. and 0.30 m w.e. for glaciers within Manas and Niyang river basins, respectively. Furthermore, this study reveals that topographical and climatic factors differentially influence GMB simulations in maritime and continental glaciers, providing key insights into glacier dynamics in response to climate change. In summary, ML, particularly the GBDT model, demonstrates significant potential in GMB simulation. Moreover, the application of ML can enhance the accuracy of GMB modeling, providing a promising approach to assess the impacts of climate change on glacier dynamics.

OBJECTIVE : To evaluate the diagnostic performance of two different shear wave elastography (SWE) techniques in distinguishing malignant breast lesions from benign ones. MATERIALS AND METHODS : From March 2016 to May 2016, a total of 153 breast lesio

OBJECTIVES: To prospectively evaluate the diagnostic performance of three-dimensional (3D) shear wave elastography (SWE) for breast lesions with quantitative stiffness information from transverse, sagittal and coronal planes. METHODS: Conventional ul