Sabyasachi Chakrabortty

Dr. Sabyasachi Chakrabortty

SRM University AP
orcid

Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 June 2021 in Journal of Materials Chemistry A
Verified
Journal Article
Open access
PDF file
GDGoutam Dalapati
Goutam Dalapati
HSHimani Sharma
Himani Sharma
AGAsim Guchhait
Asim Guchhait
NCNilanjan Chakrabarty
Nilanjan Chakrabarty
PBPriyanka Bamola
Priyanka Bamola
Mohit SHARMAMohit SHARMA
Mohit SHARMA
Tin dioxide (SnO2) used in various applications due to suitable band gap and tunable conductivity. It has excellent thermal, mechanical and chemical stability.

7 February 2017 in Journal of the American Chemical Society
Verified
Journal Article
Open access
Sabyasachi ChakraborttySabyasachi Chakrabortty
Sabyasachi Chakrabortty
BABikram Keshari Agrawalla
Bikram Keshari Agrawalla
ASAnne Stumper
Anne Stumper
NVNaidu M Vegi
Naidu M Vegi
SFStephan Fischer
Stephan Fischer
TWTanja Weil
Tanja Weil
Organelle-targeted photosensitization represents a promising approach in photodynamic therapy where the design of the active photosensitizer (PS) is very crucial. In this work, we developed a macromolecular PS with multiple copies of mitochondria-targeting groups and ruthenium complexes that displays highest phototoxicity toward several cancerous cell lines. In particular, enhanced anticancer activity was demonstrated in acute myeloid leukemia cell lines, where significant impairment of proliferation and clonogenicity occurs. Finally, attractive two-photon absorbing properties further underlined the great significance of this PS for mitochondria targeted PDT applications in deep tissue cancer therapy.

17 November 2012 in ACS Nano
Verified
Journal Article
Closed access
GXGuichuan Xing
Guichuan Xing
YLYile Liao
Yile Liao
XWXiangyang Wu
Xiangyang Wu
Sabyasachi ChakraborttySabyasachi Chakrabortty
Sabyasachi Chakrabortty
XLXinfeng Liu
Xinfeng Liu
TSTze-Chien Sum
Tze-Chien Sum

16 August 2021 in Sustainability
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Journal Article
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Swikriti KhadkeSwikriti Khadke
Swikriti Khadke
PGPragya Gupta
Pragya Gupta
SRShanmukh Rachakunta
Shanmukh Rachakunta
Chandreswar MahataChandreswar Mahata
Chandreswar Mahata
SDSuma Dawn
Suma Dawn
GDGoutam Dalapati
Goutam Dalapati
Global plastic waste is increasing rapidly. In general, densely populated regions generate tons of plastic waste daily, which is sometimes disposed of on land or diverged to sea. Most of the plastics created in the form of waste have complex degradation behavior and are non-biodegradable by nature. These remain intact in the environment for a long time span and potentially originate complications within terrestrial and marine life ecosystems. The strategic management of plastic waste and recycling can preserve environmental species and associated costs. The key contribution in this work focuses on ongoing efforts to utilize plastic waste by introducing blockchain during plastic waste recycling. It is proposed that the efficiency of plastic recycling can be improved enormously by using the blockchain phenomenon. Automation for the segregation and collection of plastic waste can effectively establish a globally recognizable tool using blockchain-based applications. Collection and sorting of plastic recycling are feasible by keeping track of plastic with unique codes or digital badges throughout the supply chain. This approach can support a collaborative digital consortium for efficient plastic waste management, which can bring together multiple stakeholders, plastic manufacturers, government entities, retailers, suppliers, waste collectors, and recyclers.

8 June 2024 in Biomolecules
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Journal Article
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AMArunima Mukherjee
Arunima Mukherjee
KGKrishna Kanta Ghosh
Krishna Kanta Ghosh
Sabyasachi ChakraborttySabyasachi Chakrabortty
Sabyasachi Chakrabortty
BGBalázs Gulyás
Balázs Gulyás
PPParasuraman Padmanabhan
Parasuraman Padmanabhan
WBWritoban Basu Ball
Writoban Basu Ball
Reactive oxygen species (ROS) contain at least one oxygen atom and one or more unpaired electrons and include singlet oxygen, superoxide anion radical, hydroxyl radical, hydroperoxyl radical, and free nitrogen radicals. Intracellular ROS can be formed as a consequence of several factors, including ultra-violet (UV) radiation, electron leakage during aerobic respiration, inflammatory responses mediated by macrophages, and other external stimuli or stress. The enhanced production of ROS is termed oxidative stress and this leads to cellular damage, such as protein carbonylation, lipid peroxidation, deoxyribonucleic acid (DNA) damage, and base modifications. This damage may manifest in various pathological states, including ageing, cancer, neurological diseases, and metabolic disorders like diabetes. On the other hand, the optimum levels of ROS have been implicated in the regulation of many important physiological processes. For example, the ROS generated in the mitochondria (mitochondrial ROS or mt-ROS), as a byproduct of the electron transport chain (ETC), participate in a plethora of physiological functions, which include ageing, cell growth, cell proliferation, and immune response and regulation. In this current review, we will focus on the mechanisms by which mt-ROS regulate different pathways of host immune responses in the context of infection by bacteria, protozoan parasites, viruses, and fungi. We will also discuss how these pathogens, in turn, modulate mt-ROS to evade host immunity. We will conclude by briefly giving an overview of the potential therapeutic approaches involving mt-ROS in infectious diseases.

21 September 2016 in Nano Letters
Verified
Journal Article
Closed access
WLWeina Liu
Weina Liu
BNBoris Naydenov
Boris Naydenov
Sabyasachi ChakraborttySabyasachi Chakrabortty
Sabyasachi Chakrabortty
BWBettina Wuensch
Bettina Wuensch
KHKristina Hübner
Kristina Hübner
TWTanja Weil
Tanja Weil