Safdar Khan

Dr. Safdar Khan

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Biography

I am a dedicated researcher with a strong interest in neuroendocrine regulation of reproduction, reproductive toxicology, stress-mediated regulation of reproduction, and seasonality in reproductive function. My work focuses on understanding how endocrine signals regulate reproductive processes and how external factors, such as environmental stressors and toxicants, disrupt these intricate mechanisms. One of my key research areas is neuroendocrine control of reproduction, particularly the role of kisspeptin and RFRP-3 in gonadotropic axis regulation. I have investigated how hormonal changes influence reproductive outcomes and how neuropeptides integrate environmental and physiological cues to control reproductive function. Additionally, I have explored stress-mediated alterations in reproductive hormones, examining how chronic exposure to stressors affects fertility and hormonal balance. In the field of reproductive toxicology, I have studied the impact of environmental contaminants and food preservatives, such as sodium benzoate, on reproductive health. My research evaluates dose-dependent toxic effects on gonadal function, histopathological alterations, oxidative stress, and endocrine disruption, aiming to uncover the mechanisms by which toxicants impair fertility and reproductive longevity. Moreover, I am particularly interested in seasonality and its influence on reproductive cycles, exploring how photoperiodic changes and environmental factors modulate reproductive act

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