The increasing need for economic, safe, and sustainable smart manufacturing combined with novel technological enablers has paved the way for artificial intelligence (AI) and big data in industries. This implies a substantial integration of AI, Industrial Internet of Things (IIoT), Robotics, big data, Blockchain, and 5G communications in support of smart manufacturing and the dynamical processes in modern industries. In this article, we provide a comprehensive overview of different aspects of AI and big data in Industry 4.0 with a particular focus on key applications, techniques, the concepts involved, key enabling technologies, challenges, and research perspective toward deployment of Industry 5.0. In detail, we highlight and analyze how the duo of AI and big data is helping in different applications of Industry 4.0. We also highlight key challenges in a successful deployment of AI and big data solutions in smart industrial applications with a particular emphasis on data-related issues, such as availability, bias, auditing, management, interpretability, communication, and different adversarial attacks and security issues. Finally, we explore the significance of AI and big data toward Industry 4.0 applications through panoramic reviews and discussions. This work is expected to provide a baseline for future research in the domain.

Metaverse has evolved as one of the popular research agendas that let users learn, socialize, and collaborate in a networked three-dimensional (3D) immersive virtual world. Due to the rich multimedia streaming capability and immersive user experience with high-speed communication, the metaverse is an ideal model for education, training, and skill development tasks. To facilitate research in this area, we provide a comprehensive review of the various educational use cases and explore how enabling technologies such as Extended reality (XR) and the Internet of Everything (IoE) will play a major role in educational services in future metaverses. Secondly, we provide an overview of metaverse-based educational applications focusing on education, training, and skill development and analyze the technologies they are built upon. We identify common research problems and future research directions in the domain. The paper also identifies core ethical considerations of metaverse for education and potential pitfalls. We believe this survey can fully demonstrate the versatility of metaverse-driven education, which could serve as a potential guideline for the researchers.

Explainable Artificial Intelligence (XAI) is transforming the field of Artificial Intelligence (AI) by enhancing the trust of end-users in machines. As the number of connected devices keeps on growing, the Internet of Things (IoT) market needs to be trustworthy for the end-users. However, existing literature still lacks a systematic and comprehensive survey work on the use of XAI for IoT. To bridge this lacking, in this paper, we address the XAI frameworks with a focus on their characteristics and support for IoT. We illustrate the widely-used XAI services for IoT applications, such as security enhancement, Internet of Medical Things (IoMT), Industrial IoT (IIoT), and Internet of City Things (IoCT). We also suggest the implementation choice of XAI models over IoT systems in these applications with appropriate examples and summarize the key inferences for future works. Moreover, we present the cutting-edge development in edge XAI structures and the support of sixth-generation (6G) communication services for IoT applications, along with key inferences. In a nutshell, this paper constitutes the first holistic compilation on the development of XAI-based frameworks tailored for the demands of future IoT use cases.

The field of drug discovery has experienced a remarkable transformation with the advent of artificial intelligence (AI) and machine learning (ML) technologies. However, as these AI and ML models are becoming more complex, there is a growing need for transparency and interpretability of the models. Explainable Artificial Intelligence (XAI) is a novel approach that addresses this issue and provides a more interpretable understanding of the predictions made by machine learning models. In recent years, there has been an increasing interest in the application of XAI techniques to drug discovery. This review article provides a comprehensive overview of the current state-of-the-art in XAI for drug discovery, including various XAI methods, their application in drug discovery, and the challenges and limitations of XAI techniques in drug discovery. The article also covers the application of XAI in drug discovery, including target identification, compound design, and toxicity prediction. Furthermore, the article suggests potential future research directions for the application of XAI in drug discovery. This review article aims to provide a comprehensive understanding of the current state of XAI in drug discovery and its potential to transform the field.

In the context of smart cities, ensuring road safety is crucial due to increasing urbanization and the interconnected nature of contemporary urban environments. Leveraging innovative technologies is essential to mitigate risks and create safer communities. Thus, there is a compelling imperative to develop advanced solutions to enhance road safety within smart city frameworks. In this article, we introduce a comprehensive vehicle safety framework tailored specifically for smart cities in the realm of Artificial Intelligence of Things (AIoT). This framework seamlessly integrates a variety of sensors, including eye blink, ultrasonic, and alcohol sensors, to bolster road safety. The utilization of eye blink sensor serves to promptly detect potential hazards, alerting drivers through audible cues and thereby enhancing safety on smart city roads. Moreover, ultrasonic sensors provide real time information about surrounding vehicle speeds, thereby facilitating smoother traffic flow. To address concerns related to alcohol consumption and its potential impact on road safety, our framework incorporates a specialized sensor that effectively monitors the driver’s alcohol levels. In instances of high alcohol content, the system utilizes GPS and GSM technology to automatically adjust the vehicle’s speed while simultaneously notifying pertinent authorities for prompt intervention. Additionally, our proposed system optimizes inter-vehicle communication in smart cities by leveraging Li-Fi technology, enabling faster and more efficient data transmission via visible light communication (VLC). The integration of Li-Fi enhances connectivity among connected vehicles, contributing to a more cohesive and intelligent urban transportation network. Through the structured integration of AIoT technologies, our framework lays a robust foundation for a safer, smarter, and more sustainable future in smart city transportation. It offers significant advancements in road safety and establishes the groundwork for further enhancement in intelligent urban transportation networks.

The Metaverse represents an always-on 3D network of virtual spaces, designed to facilitate social interaction, learning, collaboration, and a wide range of activities. This emerging computing platform originates from the dynamic convergence of Extended Reality (XR), Artificial Intelligence of Things (AIoT), and platform-mediated everyday life experiences in smart cities. However, the research community faces a pressing challenge in addressing the limitations posed by the resource constraints associated with XR-enabled IoT applications within the Internet of City Things (IoCT). Additionally, there is a limited understanding of the synergies between XR and AIoT technologies in the Metaverse and their implications for IoT applications within this framework. Therefore, this study provides a detailed overview of the literature on the potential applications, opportunities, and challenges pertaining to the deployment of XR technologies in IoT applications within the broader framework of IoCT. The primary focus is on navigating the challenges pertaining to the IoT applications powered by VR and AR as key components of MR in the Metaverse. This study also explores the emerging computing paradigm of AIoT and its synergistic interplay with XR technologies in the Metaverse and in relation to future IoT applications in the realm of IoCT. This study’s contributions encompass a comprehensive literature overview of XR technologies in IoT and IoCT, providing a valuable resource for researchers and practitioners. It identifies challenges and resource constraints, identifying areas that require further investigation. It fosters interdisciplinary insights into XR, IoT, AIoT, smart cities, and IoCT, bridging the gap between them. Lastly, it offers innovation pathways for effective XR deployment in future IoT/AIoT applications within IoCT. These contributions collectively advance our understanding of synergistic opportunities and complementary strengths of cutting-edge technologies for advancing the emerging paradigms of urban development.