The water supply network is of great importance for a city, and it faces various risks such as leaks and breaks, so its risk level needs to be evaluated regularly. To propose a new and efficient method to evaluate the risk level of water supply network operation, an evaluation index system of water supply network has been established, the proportion of each evaluation factor is calculated by Analytic Network Process (ANP). On this basis, the model based on the ANP-fuzzy comprehensive evaluation method is established, and the risk level of the water supply network in the Yangtze River Delta is evaluated through a program compiled by the authors. The spatial maps are used to show the impacted pipelines clearly. The results showed that most of the pipelines in the Yangtze River Delta are in a good state, and only some pipelines need to be repaired.