This page has only limited features, please log in for full access.

Dr. Antonio Lavazza
Istituto Zooprofilattico della Lombardia e dell'Emilia-Romagna "Bruno Ubertini"

Basic Info


Research Keywords & Expertise

0 Electron Microscopy
0 Wildlife
0 diagnosis
0 prophylaxis
0 viral diseases

Fingerprints

Electron Microscopy
diagnosis
Wildlife

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 30 August 2021 in Animals
Reads 0
Downloads 0

Whilst multiple countries in Europe have wildlife health surveillance (WHS) programmes, they vary in scope. In many countries, coordinated general surveillance at a national scale is not conducted and the knowledge of wildlife health status in Europe remains limited. Learning lessons from countries with established systems may help others to effectively implement WHS schemes. In order to facilitate information exchange, the WHS Network of the European Wildlife Disease Association organised a workshop to both collate knowledge and experience from countries that had started or expanded WHS programmes and to translate this information into practical recommendations. Presentations were given by invited representatives of European countries with different WHS levels. Events that led to the start-up and fostered growth spurts of WHS were highlighted, including action plan creation, partnership formation, organisation restructuring and appraisal by external audit. Challenges to programme development, such as a lack of funding, data sharing, infrastructural provision and method harmonisation, were explored. Recommendations to help overcome key challenges were summarised as: understanding and awareness; cross-sectoral scope; national-scale collaboration; harmonisation of methods; government support; academic support; other funding support; staff expertise and capacity; leadership, feedback and engagement; and threat mitigation and wildlife disease management. This resource may enable the development of WHS programmes in Europe and beyond.

ACS Style

Becki Lawson; Aleksija Neimanis; Antonio Lavazza; Jorge Ramón López-Olvera; Paul Tavernier; Charalambos Billinis; J. Paul Duff; Daniel T. Mladenov; Jolianne M. Rijks; Sara Savić; Gudrun Wibbelt; Marie-Pierre Ryser-Degiorgis; Thijs Kuiken. How to Start Up a National Wildlife Health Surveillance Programme. Animals 2021, 11, 2543 .

AMA Style

Becki Lawson, Aleksija Neimanis, Antonio Lavazza, Jorge Ramón López-Olvera, Paul Tavernier, Charalambos Billinis, J. Paul Duff, Daniel T. Mladenov, Jolianne M. Rijks, Sara Savić, Gudrun Wibbelt, Marie-Pierre Ryser-Degiorgis, Thijs Kuiken. How to Start Up a National Wildlife Health Surveillance Programme. Animals. 2021; 11 (9):2543.

Chicago/Turabian Style

Becki Lawson; Aleksija Neimanis; Antonio Lavazza; Jorge Ramón López-Olvera; Paul Tavernier; Charalambos Billinis; J. Paul Duff; Daniel T. Mladenov; Jolianne M. Rijks; Sara Savić; Gudrun Wibbelt; Marie-Pierre Ryser-Degiorgis; Thijs Kuiken. 2021. "How to Start Up a National Wildlife Health Surveillance Programme." Animals 11, no. 9: 2543.

Brief report
Published: 10 August 2021 in Viruses
Reads 0
Downloads 0

Phleboviruses are arboviruses transmitted by sand flies, mosquitoes and ticks. Some sand fly-borne phleboviruses cause illnesses in humans, such as the summer fevers caused by the Sicilian and Naples viruses or meningitis caused by the Toscana virus. Indeed, traces of several phleboviral infections have been serologically detected in domestic animals, but their potential pathogenic role in vertebrates other than humans is still unclear, as is the role of vertebrates as potential reservoirs of these viruses. In this study, we report the results of a serological survey performed on domestic animals sampled in Northern Italy, against four phleboviruses isolated from sand flies in the same area. The sera of 23 dogs, 165 sheep and 23 goats were tested with a virus neutralization assay for Toscana virus, Fermo virus, Ponticelli I virus and Ponticelli III virus. Neutralizing antibodies against one or more phleboviruses were detected in four out of 23 dogs, 31 out of 165 sheep and 12 out of 23 goats. This study shows preliminary evidence for the distribution pattern of phleboviral infections in different animal species, highlighting the potential infection of the Toscana virus in dogs and the Fermo virus in goats.

ACS Style

Davide Lelli; Vittorio Scanferla; Ana Moreno; Enrica Sozzi; Valentina Ravaioli; Maria Renzi; Giovanni Tosi; Michele Dottori; Antonio Lavazza; Mattia Calzolari. Serological Evidence of Phleboviruses in Domestic Animals on the Pre-Apennine Hills (Northern Italy). Viruses 2021, 13, 1577 .

AMA Style

Davide Lelli, Vittorio Scanferla, Ana Moreno, Enrica Sozzi, Valentina Ravaioli, Maria Renzi, Giovanni Tosi, Michele Dottori, Antonio Lavazza, Mattia Calzolari. Serological Evidence of Phleboviruses in Domestic Animals on the Pre-Apennine Hills (Northern Italy). Viruses. 2021; 13 (8):1577.

Chicago/Turabian Style

Davide Lelli; Vittorio Scanferla; Ana Moreno; Enrica Sozzi; Valentina Ravaioli; Maria Renzi; Giovanni Tosi; Michele Dottori; Antonio Lavazza; Mattia Calzolari. 2021. "Serological Evidence of Phleboviruses in Domestic Animals on the Pre-Apennine Hills (Northern Italy)." Viruses 13, no. 8: 1577.

Journal article
Published: 10 August 2021 in Insects
Reads 0
Downloads 0

Honeybee and general pollinator decline is extensively reported in many countries, adding new concern to the general biodiversity loss. Many studies were addressed to assess the causes of pollinator decline, concluding that in most cases multi-stress effects were the most probable ones. In this research, the combined effects of two possible stress sources for bees, pesticides and electromagnetic fields (multi-stress conditions), were analyzed in the field. Three experimental sites were chosen: a control one far from direct anthropogenic stress sources, a pesticide-stress site and multi-stress one, adding to the same exposure to pesticides the presence of an electromagnetic field, coming from a high-voltage electric line. Experimental apiaries were monitored weekly for one year (from April 2017 to April 2018) by means of colony survival, queen activity, storage and brood amount, parasites and pathogens, and several biomarkers in young workers and pupae. Both exposure and effect biomarkers were analysed: among the first, acetylcholinesterase (AChE), catalase (CAT), glutathione S-transferase (GST) and alkaline phosphatase (ALP) and Reactive Oxygen Species (ROS); and among the last, DNA fragmentation (DNAFRAGM) and lipid peroxidation (LPO). Results showed that bee health conditions were the worst in the multi-stress site with only one colony alive out of the four ones present at the beginning. In this site, a complex picture of adverse effects was observed, such as disease appearance (American foulbrood), higher mortality in the underbaskets (common to pesticide-stress site), behavioral alterations (queen changes, excess of honey storage) and biochemical anomalies (higher ALP activity at the end of the season). The overall results clearly indicate that the multi-stress conditions were able to induce biochemical, physiological and behavioral alterations which severely threatened bee colony survival.

ACS Style

Daniela Lupi; Marco Palamara Mesiano; Agnese Adani; Roberto Benocci; Roberto Giacchini; Paolo Parenti; Giovanni Zambon; Antonio Lavazza; Maria Boniotti; Stefano Bassi; Mario Colombo; Paolo Tremolada. Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure. Insects 2021, 12, 716 .

AMA Style

Daniela Lupi, Marco Palamara Mesiano, Agnese Adani, Roberto Benocci, Roberto Giacchini, Paolo Parenti, Giovanni Zambon, Antonio Lavazza, Maria Boniotti, Stefano Bassi, Mario Colombo, Paolo Tremolada. Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure. Insects. 2021; 12 (8):716.

Chicago/Turabian Style

Daniela Lupi; Marco Palamara Mesiano; Agnese Adani; Roberto Benocci; Roberto Giacchini; Paolo Parenti; Giovanni Zambon; Antonio Lavazza; Maria Boniotti; Stefano Bassi; Mario Colombo; Paolo Tremolada. 2021. "Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure." Insects 12, no. 8: 716.

Journal article
Published: 02 August 2021 in Viruses
Reads 0
Downloads 0

Equid and asinine gammaherpesviruses (GHVs; genus Percavirus) are members of the Herpesviridae family. Though GHVs have been reported in horse populations, less studies are available on gammaherpesviral infections in donkeys. This study reports the co-infection with two GHVs in Pantesco breed donkeys, an endangered Italian donkey breed. Samples (n = 124) were collected on a breeding farm in Southern Italy from 40 donkeys, some of which were healthy or presented erosive tongue lesions and/or mild respiratory signs. Samples were analysed by using a set of nested PCRs targeting the DNA polymerase, glycoprotein B, and DNA-packaging protein genes, and sequence and phylogenetic analyses were performed. Twenty-nine donkeys (72.5%) tested positive, and the presence of Equid gammaherpesvirus 7 and asinine herpesvirus 5 was evidenced. In 11 animals, we found evidence for co-infection with viruses from the two species. Virions with herpesvirus-like morphology were observed by electron microscopic examination, and viruses were successfully isolated in RK-13-KY cell monolayers. The histological evaluation of tongue lesions revealed moderate lympho-granulocytic infiltrates and rare eosinophilic inclusions. The detection of GHVs in this endangered asinine breed suggests the need long-life monitoring within conservation programs and reinforces the need for further investigations of GHV’s pathogenetic role in asinine species.

ACS Style

Francesco Mira; Marta Canuti; Santina Di Bella; Roberto Puleio; Antonio Lavazza; Davide Lelli; Domenico Vicari; Giuseppa Purpari; Vincenza Cannella; Gabriele Chiaramonte; Giorgia Schirò; Calogero Castronovo; Annalisa Guercio. Detection and Molecular Characterization of Two Gammaherpesviruses from Pantesco Breed Donkeys during an Outbreak of Mild Respiratory Disease. Viruses 2021, 13, 1527 .

AMA Style

Francesco Mira, Marta Canuti, Santina Di Bella, Roberto Puleio, Antonio Lavazza, Davide Lelli, Domenico Vicari, Giuseppa Purpari, Vincenza Cannella, Gabriele Chiaramonte, Giorgia Schirò, Calogero Castronovo, Annalisa Guercio. Detection and Molecular Characterization of Two Gammaherpesviruses from Pantesco Breed Donkeys during an Outbreak of Mild Respiratory Disease. Viruses. 2021; 13 (8):1527.

Chicago/Turabian Style

Francesco Mira; Marta Canuti; Santina Di Bella; Roberto Puleio; Antonio Lavazza; Davide Lelli; Domenico Vicari; Giuseppa Purpari; Vincenza Cannella; Gabriele Chiaramonte; Giorgia Schirò; Calogero Castronovo; Annalisa Guercio. 2021. "Detection and Molecular Characterization of Two Gammaherpesviruses from Pantesco Breed Donkeys during an Outbreak of Mild Respiratory Disease." Viruses 13, no. 8: 1527.

Journal article
Published: 03 February 2021 in Viruses
Reads 0
Downloads 0

Mammalian orthoreoviruses (MRVs) are emerging infectious agents that may affect wild animals. MRVs are usually associated with asymptomatic or mild respiratory and enteric infections. However, severe clinical manifestations have been occasionally reported in human and animal hosts. An insight into their circulation is essential to minimize the risk of diffusion to farmed animals and possibly to humans. The aim of this study was to investigate the presence of likely zoonotic MRVs in wild ungulates. Liver samples were collected from wild boar, red deer, roe deer, and chamois. Samples originated from two areas (Sondrio and Parma provinces) in Northern Italy with different environmental characteristics. MRV detection was carried out by PCR; confirmation by sequencing and typing for MRV type 3, which has been frequently associated with disease in pigs, were carried out for positive samples. MRV prevalence was as high as 45.3% in wild boars and 40.6% in red deer in the Sondrio area, with lower prevalence in the Parma area (15.4% in wild boars). Our findings shed light on MRV occurrence and distribution in some wild species and posed the issue of their possible role as reservoir.

ACS Style

Sara Arnaboldi; Francesco Righi; Virginia Filipello; Tiziana Trogu; Davide Lelli; Alessandro Bianchi; Silvia Bonardi; Enrico Pavoni; Barbara Bertasi; Antonio Lavazza. Mammalian Orthoreovirus (MRV) Is Widespread in Wild Ungulates of Northern Italy. Viruses 2021, 13, 238 .

AMA Style

Sara Arnaboldi, Francesco Righi, Virginia Filipello, Tiziana Trogu, Davide Lelli, Alessandro Bianchi, Silvia Bonardi, Enrico Pavoni, Barbara Bertasi, Antonio Lavazza. Mammalian Orthoreovirus (MRV) Is Widespread in Wild Ungulates of Northern Italy. Viruses. 2021; 13 (2):238.

Chicago/Turabian Style

Sara Arnaboldi; Francesco Righi; Virginia Filipello; Tiziana Trogu; Davide Lelli; Alessandro Bianchi; Silvia Bonardi; Enrico Pavoni; Barbara Bertasi; Antonio Lavazza. 2021. "Mammalian Orthoreovirus (MRV) Is Widespread in Wild Ungulates of Northern Italy." Viruses 13, no. 2: 238.

Journal article
Published: 13 January 2021 in Viruses
Reads 0
Downloads 0

Canine distemper (CD) is a fatal, highly contagious disease of wild and domestic carnivores. In the Alpine territory, several outbreaks have occurred in the past few decades within wild populations. This study investigated the presence of canine distemper virus (CDV) infections in wild carnivores in Lombardy, relating to the different circulating genotypes. From 2018 to 2020, foxes, badgers, and martens collected during passive surveillance were subjected to necropsy and histological examination, showing classical signs and microscopic lesions related to CDV. Pools of viscera from each animal were analysed by molecular methods and immunoelectron microscopy. Total prevalences of 39.7%, 52.6%, and 14.3% were recorded in foxes, badgers, and stone martens, respectively. A phylogenetic analysis showed that the sequences obtained belonged to the European 1 lineage and were divided into two different clades (a and b) according to the geographical conformation of alpine valleys included in the study. Clade a was related to the European outbreaks originating from Germany in 2006–2010, while clade b was closely related to the CDV sequences originating from northeastern Italy during the 2011–2018 epidemic wave. Our results suggest that CDV is currently well adapted to wild carnivores, mostly circulating with subclinical manifestations and without severe impact on the dynamics of these populations.

ACS Style

Tiziana Trogu; Sabrina Canziani; Sara Salvato; Alessandro Bianchi; Irene Bertoletti; Lucia Rita Gibelli; Giovanni Loris Alborali; Ilaria Barbieri; Alessandra Gaffuri; Giovanni Sala; Enrica Sozzi; Davide Lelli; Antonio Lavazza; Ana Moreno. Canine Distemper Outbreaks in Wild Carnivores in Northern Italy. Viruses 2021, 13, 99 .

AMA Style

Tiziana Trogu, Sabrina Canziani, Sara Salvato, Alessandro Bianchi, Irene Bertoletti, Lucia Rita Gibelli, Giovanni Loris Alborali, Ilaria Barbieri, Alessandra Gaffuri, Giovanni Sala, Enrica Sozzi, Davide Lelli, Antonio Lavazza, Ana Moreno. Canine Distemper Outbreaks in Wild Carnivores in Northern Italy. Viruses. 2021; 13 (1):99.

Chicago/Turabian Style

Tiziana Trogu; Sabrina Canziani; Sara Salvato; Alessandro Bianchi; Irene Bertoletti; Lucia Rita Gibelli; Giovanni Loris Alborali; Ilaria Barbieri; Alessandra Gaffuri; Giovanni Sala; Enrica Sozzi; Davide Lelli; Antonio Lavazza; Ana Moreno. 2021. "Canine Distemper Outbreaks in Wild Carnivores in Northern Italy." Viruses 13, no. 1: 99.

Journal article
Published: 28 August 2020 in Vaccines
Reads 0
Downloads 0

Inactivated strain-specific vaccines have been successfully used to control rabbit haemorrhagic disease (RHD) caused by RHDV-2 in the rabbit industry. It is unknown whether and how vaccination of breeding does contributed to protect the population of young susceptible rabbit kits. The present study investigates whether the immunity against RHDV-2 produced by vaccination of breeding does is transmitted to their progeny and its dynamic once inherited by kits. For this purpose, New Zealand female rabbits of 8–9 weeks of age were allocated into 2 groups of 40 subjects each and bred during 6 reproductive cycles. The first experimental group was vaccinated with a commercially available inactivated vaccine against RHDV-2 whereas the second group was inoculated with PBS. Moreover, the present study was also meant to identify the mechanisms of transmission of that maternal immunity. For this reason, rabbit kits of vaccinated and non-vaccinated breeding does were cross-fostered before milk uptake. The RHDV-2 antibody response was monitored in the blood serum of breeding does and of their kits by competition ELISA (cELISA) and solid-phase ELISA (spELISA). Since it has been clearly demonstrated that cELISA positive rabbits are protected from RHD, we avoided the resorting of the challenge of the kits with RHDV-2. Results showed that RHDV-2 antibodies were inherited by kits up to one year from vaccination of breeding does. Once inherited, the maternally derived antibody response against RHDV-2 lasted at least until 28 days of life. Finally, the study also elucidated that the major contribution to the maternal derived immunity against RHDV-2 in kits was provided during gestation and probably transmitted through transplacental mechanisms although lactation provided a little contribution to it. The present study contributed to elucidate the characteristics of the maternal antibody immunity produced by vaccination and its mechanisms of transmission.

ACS Style

Massimiliano Baratelli; Joan Molist Badiola; Alba Puigredon-Fontanet; Mariam Pascual; Oriol Boix; Francesc Xavier Mora-Igual; Michelle Woodward; Antonio Lavazza; Lorenzo Capucci. Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine. Vaccines 2020, 8, 484 .

AMA Style

Massimiliano Baratelli, Joan Molist Badiola, Alba Puigredon-Fontanet, Mariam Pascual, Oriol Boix, Francesc Xavier Mora-Igual, Michelle Woodward, Antonio Lavazza, Lorenzo Capucci. Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine. Vaccines. 2020; 8 (3):484.

Chicago/Turabian Style

Massimiliano Baratelli; Joan Molist Badiola; Alba Puigredon-Fontanet; Mariam Pascual; Oriol Boix; Francesc Xavier Mora-Igual; Michelle Woodward; Antonio Lavazza; Lorenzo Capucci. 2020. "Characterization of the Maternally Derived Antibody Immunity against Rhdv-2 after Administration in Breeding Does of an Inactivated Vaccine." Vaccines 8, no. 3: 484.

Case report
Published: 17 July 2020 in Pathogens
Reads 0
Downloads 0

We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most common viral agents belonging to the family Papillomaviridae, Poxviridae and Herpesviridae which cause skin diseases in cattle. Two specimens were collected from cases clinically diagnosed as papillomatosis and pseudo-LSD. Both skin lesions were shown to harbor more than one viral species. This case report shows, for the first time, co-infection of zoonotic parapoxvirus with bovine papillomavirus and herpesvirus in skin lesions of cattle. In particular, the simultaneous presence of virions morphologically referable to parapoxvirus and papillomavirus confirms that the replication of both viruses in the same lesion can happen and the so-called papillomatosis can bear zoonotic viruses.

ACS Style

Laura Gallina; Federica Savini; Sabrina Canziani; Matteo Frasnelli; Antonio Lavazza; Alessandra Scagliarini; Davide Lelli. Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions. Pathogens 2020, 9, 583 .

AMA Style

Laura Gallina, Federica Savini, Sabrina Canziani, Matteo Frasnelli, Antonio Lavazza, Alessandra Scagliarini, Davide Lelli. Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions. Pathogens. 2020; 9 (7):583.

Chicago/Turabian Style

Laura Gallina; Federica Savini; Sabrina Canziani; Matteo Frasnelli; Antonio Lavazza; Alessandra Scagliarini; Davide Lelli. 2020. "Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions." Pathogens 9, no. 7: 583.

Journal article
Published: 11 July 2020 in Vaccines
Reads 0
Downloads 0

Pestivirus A or bovine viral diarrhoea virus (BVDV) type 1 is responsible for cosmopolitan diseases affecting cattle and other ruminants, presenting a wide range of clinical manifestations, with relevant impact on zootechnic production. The objective of the present study was to verify whether animals immunised with four commercial vaccines also developed a protective humoral immunity against other viral subgenotypes than those contained in each vaccine. Four groups of 25 bovines each were formed and vaccinated according to the manufacturer’s instructions of the commercial vaccines. On sera collected 28 days after the last vaccination, virus neutralisation tests (VNT) were performed using homologous and heterologous viruses and enzyme-linked immunosorbent assay (ELISA) methods. Finally, the VNT results were comparatively evaluated through a statistical analysis. Serological results highlighted that, although with a different degree of efficiency, the four vaccines resulted in not developing a solid antibody-mediated cross-immunity against all the strains used.

ACS Style

Enrica Sozzi; Cecilia Righi; Massimo Boldini; Moira Bazzucchi; Giulia Pezzoni; Matteo Gradassi; Stefano Petrini; Davide Lelli; Giordano Ventura; Ilaria Pierini; Ana Moreno; Emiliana Brocchi; Antonio Lavazza; Gian Mario De Mia. Cross-Reactivity Antibody Response after Vaccination with Modified Live and Killed Bovine Viral Diarrhoea Virus (BVD) Vaccines. Vaccines 2020, 8, 374 .

AMA Style

Enrica Sozzi, Cecilia Righi, Massimo Boldini, Moira Bazzucchi, Giulia Pezzoni, Matteo Gradassi, Stefano Petrini, Davide Lelli, Giordano Ventura, Ilaria Pierini, Ana Moreno, Emiliana Brocchi, Antonio Lavazza, Gian Mario De Mia. Cross-Reactivity Antibody Response after Vaccination with Modified Live and Killed Bovine Viral Diarrhoea Virus (BVD) Vaccines. Vaccines. 2020; 8 (3):374.

Chicago/Turabian Style

Enrica Sozzi; Cecilia Righi; Massimo Boldini; Moira Bazzucchi; Giulia Pezzoni; Matteo Gradassi; Stefano Petrini; Davide Lelli; Giordano Ventura; Ilaria Pierini; Ana Moreno; Emiliana Brocchi; Antonio Lavazza; Gian Mario De Mia. 2020. "Cross-Reactivity Antibody Response after Vaccination with Modified Live and Killed Bovine Viral Diarrhoea Virus (BVD) Vaccines." Vaccines 8, no. 3: 374.

Journal article
Published: 30 May 2020 in Pathogens
Reads 0
Downloads 0

A proliferative cauliflower lesion was excised from the udder of a sheep. Histological investigation confirmed the macroscopic classification of the lesion as a papilloma, without any fibroblastic proliferation. PCR revealed the presence of bovine papillomavirus (BPV), which was further confirmed by the identification of a Deltapapillomavirus 4 by Next Generation Sequencing analysis. This was subsequently classified as bovine papillomavirus type 1. Negative staining electron microscopy (EM) analyses produced negative test results for papillomavirus particles. RNA in situ hybridization (ISH) confirmed the presence of BPV-1. The results further confirm the ability of BPVs belonging to the Deltapapillomavirus genus to infect distantly related species and to cause lesions that are different from sarcoids.

ACS Style

Federica Savini; Laura Gallina; Alice Prosperi; Roberto Puleio; Antonio Lavazza; Patrizia Di Marco; Serena Tumino; Ana Moreno; Davide Lelli; Annalisa Guercio; Alessandra Scagliarini. Bovine Papillomavirus 1 Gets Out of the Flock: Detection in an Ovine Wart in Sicily. Pathogens 2020, 9, 429 .

AMA Style

Federica Savini, Laura Gallina, Alice Prosperi, Roberto Puleio, Antonio Lavazza, Patrizia Di Marco, Serena Tumino, Ana Moreno, Davide Lelli, Annalisa Guercio, Alessandra Scagliarini. Bovine Papillomavirus 1 Gets Out of the Flock: Detection in an Ovine Wart in Sicily. Pathogens. 2020; 9 (6):429.

Chicago/Turabian Style

Federica Savini; Laura Gallina; Alice Prosperi; Roberto Puleio; Antonio Lavazza; Patrizia Di Marco; Serena Tumino; Ana Moreno; Davide Lelli; Annalisa Guercio; Alessandra Scagliarini. 2020. "Bovine Papillomavirus 1 Gets Out of the Flock: Detection in an Ovine Wart in Sicily." Pathogens 9, no. 6: 429.

Journal article
Published: 17 April 2020 in Animals
Reads 0
Downloads 0

The Respirovirus genus, family Paramamixoviridae, includes respiratory viral pathogens. Here we report the identification and genetic characterization of a respirovirus in an Alpine chamois showing interstitial pneumonia associated with catarrhal bronchopneumonia. The full-genome characterization of this respirovirus, named ChamoisRV/IT2014, revealed low similarities to caprine respirovirus (77.1%), bovine respirovirus (74.5%) and human respirovirus (72.0%). The phylogenetic analyses based on the full-length genome sequence of the novel isolate and reference respirovirus strains showed that ChamoisRV/IT2014 clustered with caprine respirovirus but formed a separate branch. The phylogenetic tree topology of complete large protein amino acid sequences, representing the current species demarcation criterion for Respirovirus genus, showed a 0.05 branch length of ChamoisRV/IT2014 sequence between the nearest node and the tip of the branch, suggesting that this virus belongs to a novel species. This new isolate in a new host species raises several questions to be addressed on the epidemiological role of chamois and the risks of cross-transmission between wild ruminants and livestock.

ACS Style

Camilla Luzzago; Erika Ebranati; Antonio Lavazza; Martina Besozzi; Gianguglielmo Zehender; Paolo Lanfranchi; Stefania Lauzi. Identification and Genetic Characterization of a Novel Respirovirus in Alpine Chamois (Rupicapra rupicapra rupicapra). Animals 2020, 10, 704 .

AMA Style

Camilla Luzzago, Erika Ebranati, Antonio Lavazza, Martina Besozzi, Gianguglielmo Zehender, Paolo Lanfranchi, Stefania Lauzi. Identification and Genetic Characterization of a Novel Respirovirus in Alpine Chamois (Rupicapra rupicapra rupicapra). Animals. 2020; 10 (4):704.

Chicago/Turabian Style

Camilla Luzzago; Erika Ebranati; Antonio Lavazza; Martina Besozzi; Gianguglielmo Zehender; Paolo Lanfranchi; Stefania Lauzi. 2020. "Identification and Genetic Characterization of a Novel Respirovirus in Alpine Chamois (Rupicapra rupicapra rupicapra)." Animals 10, no. 4: 704.

Communication
Published: 01 March 2020 in Animals
Reads 0
Downloads 0

Most of the newly emerging infections arise from animal reservoirs, frequently represented by wildlife species. Western European hedgehogs (Erinaceus europaeus) are mammalian hibernators, mainly nocturnal and insectivorous, living in natural open and green spaces as well as artificial, rural and urban, areas. They are generalist predators of macro-invertebrates, but they may also eat meat, bird eggs and on occasion pet food. These ecological and feeding habits, along with their high population densities, notable synanthropic attitudes, frequent contacts with sympatric wild and domestic species, including humans, implicate the possibility of intra- and interspecies interactions accounting for the possible involvement of E. europaeus in the ecology of several potentially emerging pathogens, including coronaviruses. Using PCR-based and virus isolation methods, we found that 58.3% of 24 hedgehogs’ fecal samples were PCR-positive for Erinaceus coronaviruses (EriCoVs). We did not observe any clinical disease related to the EriCoV infection in hedgehogs. However, the high mutation rates characterizing members of the Coronaviridae family and their potential successful interspecies host jumps—as that likely occurred in the Novel coronavirus (2019-nCoV) emergence—should be considered in the management of hedgehogs admitted to multi-species wildlife rehabilitation centers, recommending their return back to the original recovery areas. The Western European Hedgehog (Erinaceus europaeus) is one of the four hedgehog species belonging to the genus Erinaceus. Among them, E. amurensis is extant in East Asia’s areas only, whereas E. europaeus, E. roumanicus and E. concolor are mainly found in Europe. E. europaeus is endemically distributed from western to central and southern Europe, including Italy. Western European hedgehogs’ ecological and feeding habits, along with their high population densities, notable synanthropic attitudes, frequent contacts with sympatric wild and domestic species, including humans, implicate the possible involvement of E. europaeus in the ecology of potentially emerging viruses, such as coronaviruses, influenza A and influenza D viruses, canine distemper virus, pestiviruses and Aujeszky’s disease virus. We examined 24 E. europaeus individuals found injured in urban and rural areas of Northern Italy. Of the 24 fecal samples collected and tested for the above-mentioned pathogens by both PCR-based and virus isolation methods, 14 were found PCR-positive for betacoronaviruses belonging to lineage C and related to the known Erinaceus coronaviruses (EriCoVs), as determined by partial sequencing of the virus genome. Our findings suggest that hedgehogs could be considered natural reservoirs of CoVs, and also act as chronic shedding carriers of these potentially emerging RNA viruses.

ACS Style

Mauro Delogu; Claudia Cotti; Davide Lelli; Enrica Sozzi; Tiziana Trogu; Antonio Lavazza; Giacomo Garuti; Maria Rita Castrucci; Gabriele Vaccari; Maria Alessandra De Marco; Ana Moreno. Eco-Virological Preliminary Study of Potentially Emerging Pathogens in Hedgehogs (Erinaceus europaeus) Recovered at a Wildlife Treatment and Rehabilitation Center in Northern Italy. Animals 2020, 10, 407 .

AMA Style

Mauro Delogu, Claudia Cotti, Davide Lelli, Enrica Sozzi, Tiziana Trogu, Antonio Lavazza, Giacomo Garuti, Maria Rita Castrucci, Gabriele Vaccari, Maria Alessandra De Marco, Ana Moreno. Eco-Virological Preliminary Study of Potentially Emerging Pathogens in Hedgehogs (Erinaceus europaeus) Recovered at a Wildlife Treatment and Rehabilitation Center in Northern Italy. Animals. 2020; 10 (3):407.

Chicago/Turabian Style

Mauro Delogu; Claudia Cotti; Davide Lelli; Enrica Sozzi; Tiziana Trogu; Antonio Lavazza; Giacomo Garuti; Maria Rita Castrucci; Gabriele Vaccari; Maria Alessandra De Marco; Ana Moreno. 2020. "Eco-Virological Preliminary Study of Potentially Emerging Pathogens in Hedgehogs (Erinaceus europaeus) Recovered at a Wildlife Treatment and Rehabilitation Center in Northern Italy." Animals 10, no. 3: 407.

Journal article
Published: 10 December 2019 in Viruses
Reads 0
Downloads 0

Atypical porcine pestivirus (APPV) is a newly recognized member of the Flaviviridae family. This novel porcine pestivirus was first described in 2015 in the USA, where it has been associated with congenital tremor type A-II in new-born piglets. APPV is widely distributed in domestic pigs in Europe and Asia. In this study, a virological survey was performed in Northern Italy to investigate the presence of APPV using molecular methods. Testing of 360 abortion samples from pig herds revealed two APPV strains from distinct provinces in the Lombardy region and testing of 430 wild boar blood samples revealed three strains, one from Lombardy and two from Emilia Romagna. The nucleotide sequencing of a fragment of the nonstructural protein 3-coding region revealed a high similarity to the previously detected European strains (Spanish, German, and Italian) of APPV.

ACS Style

Enrica Sozzi; Cristian Salogni; Davide Lelli; Ilaria Barbieri; Ana Moreno; Giovanni Loris Alborali; Antonio Lavazza. Molecular Survey and Phylogenetic Analysis of Atypical Porcine Pestivirus (APPV) Identified in Swine and Wild Boar from Northern Italy. Viruses 2019, 11, 1142 .

AMA Style

Enrica Sozzi, Cristian Salogni, Davide Lelli, Ilaria Barbieri, Ana Moreno, Giovanni Loris Alborali, Antonio Lavazza. Molecular Survey and Phylogenetic Analysis of Atypical Porcine Pestivirus (APPV) Identified in Swine and Wild Boar from Northern Italy. Viruses. 2019; 11 (12):1142.

Chicago/Turabian Style

Enrica Sozzi; Cristian Salogni; Davide Lelli; Ilaria Barbieri; Ana Moreno; Giovanni Loris Alborali; Antonio Lavazza. 2019. "Molecular Survey and Phylogenetic Analysis of Atypical Porcine Pestivirus (APPV) Identified in Swine and Wild Boar from Northern Italy." Viruses 11, no. 12: 1142.

Journal article
Published: 08 September 2019 in Cells
Reads 0
Downloads 0

Melatonin, an indole produced by pineal and extrapineal tissues, but also taken with a vegetarian diet, has strong anti-oxidant, anti-inflammatory and anti-obesogenic potentials. Non-alcoholic fatty liver disease (NAFLD) is the hepatic side of the metabolic syndrome. NAFLD is a still reversible phase but may evolve into steatohepatitis (NASH), cirrhosis and carcinoma. Currently, an effective therapy for blocking NAFLD staging is lacking. Silent information regulator 1 (SIRT1), a NAD+ dependent histone deacetylase, modulates the energetic metabolism in the liver. Micro-RNA-34a-5p, a direct inhibitor of SIRT1, is an emerging indicator of NAFLD grading. Thus, here we analyzed the effects of oral melatonin against NAFLD and underlying molecular mechanisms, focusing on steatosis, ER stress, mitochondrial shape and autophagy. Male C57BL/6J (WT) and SIRT1 heterozygous (HET) mice were placed either on a high-fat diet (58.4% energy from lard) (HFD) or on a standard maintenance diet (8.4% energy from lipids) for 16 weeks, drinking melatonin (10 mg/kg) or not. Indirect calorimetry, glucose tolerance, steatosis, inflammation, ER stress, mitochondrial changes, autophagy and microRNA-34a-5p expression were estimated. Melatonin improved hepatic metabolism and steatosis, influenced ER stress and mitochondrial shape, and promoted autophagy in WT HFD mice. Conversely, melatonin was ineffective in HET HFD mice, maintaining NASH changes. Indeed, autophagy was inconsistent in HET HFD or starved mice, as indicated by LC3II/LC3I ratio, p62/SQSTM1 and autophagosomes estimation. The beneficial role of melatonin in dietary induced NAFLD/NASH in mice was related to reduced expression of microRNA-34a-5p and sterol regulatory element-binding protein (SREBP1) but only in the presence of full SIRT1 availability.

ACS Style

Alessandra Stacchiotti; Ilaria Grossi; Raquel García-Gómez; Gaurangkumar Arvindbhai Patel; Alessandro Salvi; Antonio Lavazza; Giuseppina De Petro; Maria Monsalve; Rita Rezzani. Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. Cells 2019, 8, 1053 .

AMA Style

Alessandra Stacchiotti, Ilaria Grossi, Raquel García-Gómez, Gaurangkumar Arvindbhai Patel, Alessandro Salvi, Antonio Lavazza, Giuseppina De Petro, Maria Monsalve, Rita Rezzani. Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. Cells. 2019; 8 (9):1053.

Chicago/Turabian Style

Alessandra Stacchiotti; Ilaria Grossi; Raquel García-Gómez; Gaurangkumar Arvindbhai Patel; Alessandro Salvi; Antonio Lavazza; Giuseppina De Petro; Maria Monsalve; Rita Rezzani. 2019. "Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy." Cells 8, no. 9: 1053.

Journal article
Published: 13 August 2019 in Viruses
Reads 0
Downloads 0

Pestiviruses are distributed worldwide and are responsible for a variety of economically important diseases. They are not very host-specific, and thus sheep can be infected by well-known pestiviruses like bovine viral diarrhea virus (BVDV) and border disease virus (BDV), as well as by other recently discovered pestivirus species. The aim of this study is to describe the isolation and characterization of four pestivirus strains detected in aborted lamb fetuses from a single farm in the Brescia province (Northern Italy). A total of twelve aborted fetuses were collected and examined. After necropsy, organs were tested for the presence of infectious agents known as potential causes of abortion (Brucella spp., Listeria spp., Coxiella burnetii, Chlamydophila spp., Mycoplasma spp., Neospora caninum, and Toxoplasma gondii), and submitted to viral identification by isolation on Madin Darby bovine kidney (MDBK) cell culture and by PCR assay for Schmallenberg virus and pan-pestivirus RT-PCR real time assay. Three viral strains (Ovine/IT/1756/2017, Ovine/IT/338710-2/2017, and Ovine/IT/338710-3/2017) were isolated in the absence of cytopathic effects (CPEs) in cell cultures and identified with RT-PCR. Another pestivirus strain (Ovine/IT/16235-2/2018) was detected by PCR, but was not successfully isolated. Complete sequence genomic data of the three isolated viruses showed that they were highly similar, differed genetically from known pestivirus species, and were closely related to classical swine fever virus (CSFV). Beyond the identification of new ovine pestiviruses, this study indicates that a systematic diagnostic approach is important to identify the presence and map the distribution of both known and emerging pestiviruses.

ACS Style

Enrica Sozzi; Antonio Lavazza; Alessandra Gaffuri; Fabio Carlo Bencetti; Alice Prosperi; Davide Lelli; Chiara Chiapponi; Ana Moreno. Isolation and Full-Length Sequence Analysis of a Pestivirus from Aborted Lamb Fetuses in Italy. Viruses 2019, 11, 744 .

AMA Style

Enrica Sozzi, Antonio Lavazza, Alessandra Gaffuri, Fabio Carlo Bencetti, Alice Prosperi, Davide Lelli, Chiara Chiapponi, Ana Moreno. Isolation and Full-Length Sequence Analysis of a Pestivirus from Aborted Lamb Fetuses in Italy. Viruses. 2019; 11 (8):744.

Chicago/Turabian Style

Enrica Sozzi; Antonio Lavazza; Alessandra Gaffuri; Fabio Carlo Bencetti; Alice Prosperi; Davide Lelli; Chiara Chiapponi; Ana Moreno. 2019. "Isolation and Full-Length Sequence Analysis of a Pestivirus from Aborted Lamb Fetuses in Italy." Viruses 11, no. 8: 744.

Brief report
Published: 19 June 2019 in Viruses
Reads 0
Downloads 0

Interest in bat-related viruses has increased considerably during the last decade, leading to the discovery of a rising number of new viruses in several bat species. Poxviridae are a large, diverse family of DNA viruses that can infect a wide range of vertebrates and invertebrates. To date, only a few documented detections of poxviruses have been described in bat populations on three different continents (America, Africa, and Australia). These viruses are phylogenetically dissimilar and have diverse clinical impacts on their hosts. Herein, we report the isolation, nearly complete genome sequencing, and annotation of a novel poxvirus detected from an insectivorous bat (Hypsugo savii) in Northern Italy. The virus is tentatively named Hypsugopoxvirus (HYPV) after the bat species from which it was isolated. The nearly complete genome size is 166,600 nt and it encodes 161 genes. Genome analyses suggest that HYPV belongs to the Chordopoxvirinae subfamily, with the highest nucleotide identity (85%) to Eptesipoxvirus (EPTV) detected from a microbat Eptesicus fuscus in WA, USA, in 2011. To date, HYPV represents the first poxvirus detected in bats in Europe; thus, its viral ecology and disease associations should be investigated further.

ACS Style

Davide Lelli; Antonio Lavazza; Alice Prosperi; Enrica Sozzi; Francesca Faccin; Laura Baioni; Tiziana Trogu; Gian Luca Cavallari; Matteo Mauri; Anna Maria Gibellini; Chiara Chiapponi; Ana Moreno. Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy. Viruses 2019, 11, 568 .

AMA Style

Davide Lelli, Antonio Lavazza, Alice Prosperi, Enrica Sozzi, Francesca Faccin, Laura Baioni, Tiziana Trogu, Gian Luca Cavallari, Matteo Mauri, Anna Maria Gibellini, Chiara Chiapponi, Ana Moreno. Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy. Viruses. 2019; 11 (6):568.

Chicago/Turabian Style

Davide Lelli; Antonio Lavazza; Alice Prosperi; Enrica Sozzi; Francesca Faccin; Laura Baioni; Tiziana Trogu; Gian Luca Cavallari; Matteo Mauri; Anna Maria Gibellini; Chiara Chiapponi; Ana Moreno. 2019. "Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy." Viruses 11, no. 6: 568.

Journal article
Published: 06 June 2019 in Viruses
Reads 0
Downloads 0

Adenoviruses are important pathogens of humans and animals. Bats have been recognized as potential reservoirs of novel viruses, with some viruses being regarded as a possible zoonotic threat to humans. In this study, we report the detection and analysis of adenoviruses from different bat species in northern Italy. Upon sequence and phylogenetic analysis, based on a short diagnostic fragment of the highly-conserved DNA polymerase gene, we identified potential novel candidate adenovirus species, including an avian-like adenovirus strain. An adenovirus isolate was obtained in simian cell lines from the carcass of a Pipistrellus kuhlii, and the complete genome sequence was reconstructed using deep sequencing technologies. The virus displayed high nucleotide identity and virtually the same genome organization as the Pipistrellus pipistrellus strain PPV1, isolated in Germany in 2007. Gathering data on epidemiology and the genetic diversity of bat adenoviruses may be helpful to better understand their evolution in the mammalian and avian hosts.

ACS Style

Georgia Diakoudi; Gianvito Lanave; Ana Moreno; Chiara Chiapponi; Enrica Sozzi; Alice Prosperi; Vittorio LaRocca; Michele Losurdo; Nicola DeCaro; Vito Martella; Antonio Lavazza; Davide Lelli. Surveillance for Adenoviruses in Bats in Italy. Viruses 2019, 11, 523 .

AMA Style

Georgia Diakoudi, Gianvito Lanave, Ana Moreno, Chiara Chiapponi, Enrica Sozzi, Alice Prosperi, Vittorio LaRocca, Michele Losurdo, Nicola DeCaro, Vito Martella, Antonio Lavazza, Davide Lelli. Surveillance for Adenoviruses in Bats in Italy. Viruses. 2019; 11 (6):523.

Chicago/Turabian Style

Georgia Diakoudi; Gianvito Lanave; Ana Moreno; Chiara Chiapponi; Enrica Sozzi; Alice Prosperi; Vittorio LaRocca; Michele Losurdo; Nicola DeCaro; Vito Martella; Antonio Lavazza; Davide Lelli. 2019. "Surveillance for Adenoviruses in Bats in Italy." Viruses 11, no. 6: 523.

Virology division news
Published: 14 May 2019 in Archives of Virology
Reads 0
Downloads 0

In February 2019, following the annual taxon ratification vote, the order Mononegavirales was amended by the addition of four new subfamilies and 12 new genera and the creation of 28 novel species. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

ACS Style

Gaya K. Amarasinghe; María A. Ayllón; Yīmíng Bào; Christopher F. Basler; Sina Bavari; Kim R. Blasdell; Thomas Briese; Paul A. Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J. Buchholz; Camila Chabi-Jesus; Kartik Chandran; Chiara Chiapponi; Ian Crozier; Rik L. De Swart; Ralf G. Dietzgen; Olga Dolnik; Jan F. Drexler; Ralf Dürrwald; William G. Dundon; W. Paul Duprex; John M. Dye; Andrew J. Easton; Anthony R. Fooks; Pierre B. H. Formenty; Ron A. M. Fouchier; Juliana Freitas-Astúa; Anthony Griffiths; Roger Hewson; Masayuki Horie; Timothy H. Hyndman; Dàohóng Jiāng; Elliott W. Kitajima; Gary P. Kobinger; Hideki Kondō; Gael Kurath; Ivan V. Kuzmin; Robert A. Lamb; Antonio Lavazza; Benhur Lee; Davide Lelli; Eric M. Leroy; Jiànróng Lǐ; Piet Maes; Shin-Yi L. Marzano; Ana Moreno; Elke Mühlberger; Sergey V. Netesov; Norbert Nowotny; Are Nylund; Arnfinn L. Økland; Gustavo Palacios; Bernadett Pályi; Janusz T. Pawęska; Susan L. Payne; Alice Prosperi; Pedro Luis Ramos-González; Bertus K. Rima; Paul Rota; Dennis Rubbenstroth; Mang Shi; Peter Simmonds; Sophie J. Smither; Enrica Sozzi; Kirsten Spann; Mark D. Stenglein; David M. Stone; Ayato Takada; Robert B. Tesh; Keizō Tomonaga; Noël Tordo; Jonathan S. Towner; Bernadette Van Den Hoogen; Nikos Vasilakis; Victoria Wahl; Peter J. Walker; Lin-Fa Wang; Anna E. Whitfield; John V. Williams; F. Murilo Zerbini; Tāo Zhāng; Yong-Zhen Zhang; Jens H. Kuhn. Taxonomy of the order Mononegavirales: update 2019. Archives of Virology 2019, 164, 1967 -1980.

AMA Style

Gaya K. Amarasinghe, María A. Ayllón, Yīmíng Bào, Christopher F. Basler, Sina Bavari, Kim R. Blasdell, Thomas Briese, Paul A. Brown, Alexander Bukreyev, Anne Balkema-Buschmann, Ursula J. Buchholz, Camila Chabi-Jesus, Kartik Chandran, Chiara Chiapponi, Ian Crozier, Rik L. De Swart, Ralf G. Dietzgen, Olga Dolnik, Jan F. Drexler, Ralf Dürrwald, William G. Dundon, W. Paul Duprex, John M. Dye, Andrew J. Easton, Anthony R. Fooks, Pierre B. H. Formenty, Ron A. M. Fouchier, Juliana Freitas-Astúa, Anthony Griffiths, Roger Hewson, Masayuki Horie, Timothy H. Hyndman, Dàohóng Jiāng, Elliott W. Kitajima, Gary P. Kobinger, Hideki Kondō, Gael Kurath, Ivan V. Kuzmin, Robert A. Lamb, Antonio Lavazza, Benhur Lee, Davide Lelli, Eric M. Leroy, Jiànróng Lǐ, Piet Maes, Shin-Yi L. Marzano, Ana Moreno, Elke Mühlberger, Sergey V. Netesov, Norbert Nowotny, Are Nylund, Arnfinn L. Økland, Gustavo Palacios, Bernadett Pályi, Janusz T. Pawęska, Susan L. Payne, Alice Prosperi, Pedro Luis Ramos-González, Bertus K. Rima, Paul Rota, Dennis Rubbenstroth, Mang Shi, Peter Simmonds, Sophie J. Smither, Enrica Sozzi, Kirsten Spann, Mark D. Stenglein, David M. Stone, Ayato Takada, Robert B. Tesh, Keizō Tomonaga, Noël Tordo, Jonathan S. Towner, Bernadette Van Den Hoogen, Nikos Vasilakis, Victoria Wahl, Peter J. Walker, Lin-Fa Wang, Anna E. Whitfield, John V. Williams, F. Murilo Zerbini, Tāo Zhāng, Yong-Zhen Zhang, Jens H. Kuhn. Taxonomy of the order Mononegavirales: update 2019. Archives of Virology. 2019; 164 (7):1967-1980.

Chicago/Turabian Style

Gaya K. Amarasinghe; María A. Ayllón; Yīmíng Bào; Christopher F. Basler; Sina Bavari; Kim R. Blasdell; Thomas Briese; Paul A. Brown; Alexander Bukreyev; Anne Balkema-Buschmann; Ursula J. Buchholz; Camila Chabi-Jesus; Kartik Chandran; Chiara Chiapponi; Ian Crozier; Rik L. De Swart; Ralf G. Dietzgen; Olga Dolnik; Jan F. Drexler; Ralf Dürrwald; William G. Dundon; W. Paul Duprex; John M. Dye; Andrew J. Easton; Anthony R. Fooks; Pierre B. H. Formenty; Ron A. M. Fouchier; Juliana Freitas-Astúa; Anthony Griffiths; Roger Hewson; Masayuki Horie; Timothy H. Hyndman; Dàohóng Jiāng; Elliott W. Kitajima; Gary P. Kobinger; Hideki Kondō; Gael Kurath; Ivan V. Kuzmin; Robert A. Lamb; Antonio Lavazza; Benhur Lee; Davide Lelli; Eric M. Leroy; Jiànróng Lǐ; Piet Maes; Shin-Yi L. Marzano; Ana Moreno; Elke Mühlberger; Sergey V. Netesov; Norbert Nowotny; Are Nylund; Arnfinn L. Økland; Gustavo Palacios; Bernadett Pályi; Janusz T. Pawęska; Susan L. Payne; Alice Prosperi; Pedro Luis Ramos-González; Bertus K. Rima; Paul Rota; Dennis Rubbenstroth; Mang Shi; Peter Simmonds; Sophie J. Smither; Enrica Sozzi; Kirsten Spann; Mark D. Stenglein; David M. Stone; Ayato Takada; Robert B. Tesh; Keizō Tomonaga; Noël Tordo; Jonathan S. Towner; Bernadette Van Den Hoogen; Nikos Vasilakis; Victoria Wahl; Peter J. Walker; Lin-Fa Wang; Anna E. Whitfield; John V. Williams; F. Murilo Zerbini; Tāo Zhāng; Yong-Zhen Zhang; Jens H. Kuhn. 2019. "Taxonomy of the order Mononegavirales: update 2019." Archives of Virology 164, no. 7: 1967-1980.

Review
Published: 01 January 2019 in Journal of Wildlife Diseases
Reads 0
Downloads 0

Many infectious diseases originating from, or carried by, wildlife affect wildlife conservation and biodiversity, livestock health, or human health. We provide an update on changes in the epidemiology of 25 selected infectious, wildlife-related diseases in Europe (from 2010-16) that had an impact, or may have a future impact, on the health of wildlife, livestock, and humans. These pathogens were selected based on their: 1) identification in recent Europe-wide projects as important surveillance targets, 2) inclusion in European Union legislation as pathogens requiring obligatory surveillance, 3) presence in recent literature on wildlife-related diseases in Europe since 2010, 4) inclusion in key pathogen lists released by the Office International des Epizooties, 5) identification in conference presentations and informal discussions on a group email list by a European network of wildlife disease scientists from the European Wildlife Disease Association, or 6) identification as pathogens with changes in their epidemiology during 2010-16. The wildlife pathogens or diseases included in this review are: avian influenza virus, seal influenza virus, lagoviruses, rabies virus, bat lyssaviruses, filoviruses, canine distemper virus, morbilliviruses in aquatic mammals, bluetongue virus, West Nile virus, hantaviruses, Schmallenberg virus, Crimean-Congo hemorrhagic fever (CCHF) virus, African swine fever virus, amphibian ranavirus, hepatitis E virus, bovine tuberculosis ( Mycobacterium bovis), tularemia ( Francisella tularensis), brucellosis ( Brucella spp.), salmonellosis ( Salmonella spp.), Coxiella burnetii, chytridiomycosis, Echinococcus multilocularis, Leishmania infantum, and chronic wasting disease. Further work is needed to identify all of the key drivers of disease change and emergence, as they appear to be influencing the incidence and spread of these pathogens in Europe. We present a summary of these recent changes during 2010-16 to discuss possible commonalities and drivers of disease change and to identify directions for future work on wildlife-related diseases in Europe. Many of the pathogens are entering Europe from other continents while others are expanding their ranges inside and beyond Europe. Surveillance for these wildlife-related diseases at a continental scale is therefore important for planet-wide assessment, awareness of, and preparedness for the risks they may pose to wildlife, domestic animal, and human health.

ACS Style

Lisa Yon; J. Paul Duff; Erik O. Ågren; Károly Erdélyi; Ezio Ferroglio; Jacques Godfroid; Jean Hars; Gete Hestvik; Daniel Horton; Thijs Kuiken; Antonio Lavazza; Iwona Markowska-Daniel; An Martel; Aleksija Neimanis; Frank Pasmans; Stephen J. Price; Francisco Ruiz-Fons; Marie-Pierre Ryser-Degiorgis; Frederik Widén; Dolores Gavier-Widén; Dan Horton. RECENT CHANGES IN INFECTIOUS DISEASES IN EUROPEAN WILDLIFE. Journal of Wildlife Diseases 2019, 55, 3 -43.

AMA Style

Lisa Yon, J. Paul Duff, Erik O. Ågren, Károly Erdélyi, Ezio Ferroglio, Jacques Godfroid, Jean Hars, Gete Hestvik, Daniel Horton, Thijs Kuiken, Antonio Lavazza, Iwona Markowska-Daniel, An Martel, Aleksija Neimanis, Frank Pasmans, Stephen J. Price, Francisco Ruiz-Fons, Marie-Pierre Ryser-Degiorgis, Frederik Widén, Dolores Gavier-Widén, Dan Horton. RECENT CHANGES IN INFECTIOUS DISEASES IN EUROPEAN WILDLIFE. Journal of Wildlife Diseases. 2019; 55 (1):3-43.

Chicago/Turabian Style

Lisa Yon; J. Paul Duff; Erik O. Ågren; Károly Erdélyi; Ezio Ferroglio; Jacques Godfroid; Jean Hars; Gete Hestvik; Daniel Horton; Thijs Kuiken; Antonio Lavazza; Iwona Markowska-Daniel; An Martel; Aleksija Neimanis; Frank Pasmans; Stephen J. Price; Francisco Ruiz-Fons; Marie-Pierre Ryser-Degiorgis; Frederik Widén; Dolores Gavier-Widén; Dan Horton. 2019. "RECENT CHANGES IN INFECTIOUS DISEASES IN EUROPEAN WILDLIFE." Journal of Wildlife Diseases 55, no. 1: 3-43.

Perspective
Published: 21 December 2018 in Cells
Reads 0
Downloads 0

The interplay of mitochondria with the endoplasmic reticulum and their connections, called mitochondria-ER contacts (MERCs) or mitochondria-associated ER membranes (MAMs), are crucial hubs in cellular stress. These sites are essential for the passage of calcium ions, reactive oxygen species delivery, the sorting of lipids in whole-body metabolism. In this perspective article, we focus on microscopic evidences of the pivotal role of MERCs/MAMs and their changes in metabolic diseases, like obesity, diabetes, and neurodegeneration.

ACS Style

Alessandra Stacchiotti; Gaia Favero; Antonio Lavazza; Raquel Garcia-Gomez; Maria Monsalve; Rita Rezzani. Perspective: Mitochondria-ER Contacts in Metabolic Cellular Stress Assessed by Microscopy. Cells 2018, 8, 5 .

AMA Style

Alessandra Stacchiotti, Gaia Favero, Antonio Lavazza, Raquel Garcia-Gomez, Maria Monsalve, Rita Rezzani. Perspective: Mitochondria-ER Contacts in Metabolic Cellular Stress Assessed by Microscopy. Cells. 2018; 8 (1):5.

Chicago/Turabian Style

Alessandra Stacchiotti; Gaia Favero; Antonio Lavazza; Raquel Garcia-Gomez; Maria Monsalve; Rita Rezzani. 2018. "Perspective: Mitochondria-ER Contacts in Metabolic Cellular Stress Assessed by Microscopy." Cells 8, no. 1: 5.