Behavioral observation plays an essential role in the diagnosis of Autism Spectrum Disorder (ASD) by analyzing children’s atypical patterns in social activities (e.g., impaired social interaction, restricted interests, and repetitive behavior). To date, this process still heavily relies on the questionnaire survey, clinical observation, or retrospective video analysis, leading to high demand for professionals with massive labor costs. This paper proposes a standardized platform for stimulating, gathering, analyzing, modeling, and interpreting human behavioral data in the application of computer-aided ASD diagnosis. By a structured assessment process, the proposed system can automatically evaluate children’s multiple social interaction skills using the captured audio-visual data and provide the final diagnostic suggestions. We collect a multimodal behavioral database of 95 participants (71 children with ASD and 24 age-matched typical controls) in a real clinic environment, the Third Affiliated Hospital of Sun Yat-sen University, China. On the clinical database, our proposed computer-aided ASD diagnosis system obtains an accuracy of 88.42% for identifying ASD children with an average age of 24 months, representing a performance comparable to top-level human experts. As a unified and replicable solution, it has good potential to be promoted to less developed areas with limited high-quality medical resources.

Capturing the dynamics of facial expression progression in video is an essential and challenging task for facial expression recognition (FER). In this paper, we propose an effective framework to address this challenge. We develop a C3D-based network architecture, 3D-Inception-ResNet, to extract spatial-temporal features from the dynamic facial expression image sequence. A Spatial-Temporal and Channel Attention Module (STCAM) is proposed to explicitly exploit the holistic spatial-temporal and channel-wise correlations among the extracted features. Specifically, the proposed STCAM calculates a channel-wise and a spatial-temporal-wise attention map to enhance the features along the corresponding feature dimensions for more representative features. We evaluate our method on three popular dynamic facial expression recognition datasets, CK+, Oulu-CASIA and MMI. Experimental results show that our method achieves better or comparable performance compared to the state-of-the-art approaches.

Head pose estimation is an important step for many human-computer interaction applications such as face detection, facial recognition, and facial expression classification. Accurate head pose estimation benefits these applications that require face images as the input. Most head pose estimation methods suffer from perspective distortion because the users do not always align their face perfectly with the camera. This paper presents a new approach that uses image rectification to reduce the negative effect of perspective distortion and a lightweight convolutional neural network to obtain highly accurate head pose estimations. The proposed method calculates the angle between the optical axis of the camera and the projection vector of the center of the face. The face image is rectified using this estimated angle through perspective transformation. A lightweight network that is only 0.88 MB in size is designed to take the rectified face image as the input to perform head pose estimation. The output of the network, the head pose estimation of the rectified face image, is transformed back to the camera coordinate system as the final head pose estimation. Experiments on public benchmark datasets show that the proposed image rectification method and the newly designed lightweight network improve the accuracy of head pose estimation remarkably. Compared with state-of-the-art methods, our approach achieves both higher accuracy and faster processing speed.