Currently, a large amount of pharmaceutical waste (PW) and its derivatives are being produced and, in some cases, inadequate management or treatment practices are applied. In this regard, this research explores the adoption of several alternatives to deal with these problems, including biocarbon within the framework of the circular economy. Photocatalytic nanomaterials have been also extensively discussed as a feasible way to remove pharmaceutical compounds in wastewater. Although there are existing reports in this area, this document provides a detailed study of the synthesis process, experimental conditions, the integration of photocatalysts, and their impact on enhancing photocatalytic efficiency. Additionally, the low cost and ease of fabrication of lab-scale microbial fuel cells (MFCs) are thoroughly examined. This innovative technology not only facilitates the degradation of hazardous compounds in wastewater but also harnesses their energy to generate electricity simultaneously. The aforementioned approaches are covered and discussed in detail by documenting interesting recently published research and case studies worldwide. Furthermore, this research is of significant importance because it addresses the valorization of PW by generating valuable by-products, such as H₂ and O₂, which can occur simultaneously during the photodegradation process, contributing to more sustainable industrial practices and clean energy technologies.

Currently, some concerns regarding the potential toxicity of nanoparticles (NP) on the environment have emerged. The effect of ZnO, TiO2, and Fe2O3 NP on corn (Zea mays L.), common beans (Phaseolus vulgaris L.), nanobioremediation of polycyclic aromatic hydrocarbons (PAH), and soil organisms from agricultural or forest soils was studied at laboratory, greenhouse, and land level. The samples were analyzed by X-ray diffraction (XRD), field emission scanning electron microscopy with X-ray energy dispersion spectrometry (FESEM-EDS), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS) gas chromatography (GC), ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS) and Fourier transform infrared spectrometry with attenuated total reflectance (FTIR-ATR). ZnO-NP did not harm the mycorrhizal root colonization but, the presence of ZnO-NP decreased the degradation of PAH. The synthesis of metabolites from corn was more affected by the PAH than by ZnO-NP. FTIR spectra showed that NP affected the synthesis of compounds from specific functional groups in common bean plants. Fe2O3-NP were attached to the body of forest-soil organisms and significantly increased the concentration of Fe in their body, while TiO2-NP changed the morphological tissue of roots and stems of common bean as witnessed by micrographs of longitudinal and cross-sections. The NP used in this research significantly changed some response variables on the experiments carried-out at laboratory, greenhouse, and land level.