In this paper, a new asymptotic-numerical approach to solving an inverse boundary value problem for a nonlinear singularly perturbed parabolic equation with time-periodic coefficients is proposed. An unknown boundary condition is reconstructed by using known additional information about the location of a moving front. An asymptotic analysis of the direct problem allows us to reduce the original inverse problem to that with a simpler numerical solution. Numerical examples demonstrate the efficiency of the method.

In this paper we apply the notion of quasi-solution to nonlinear inverse coefficient problems. Instead of a compact set M we use the ball B(0, r) in which the radius r occurred to be sometimes a regularization parameter. Moreover this constant allows one to estimate the convergence rate for many well-known algorithms for solving inverse coefficient problems and to decrease crucially the number of iterations.

We investigate inverse problems of finding unknown parameters of mathematical models SEIR-HCD and SEIR-D of COVID-19 spread with additional information about the number of detected cases, mortality, self-isolation coefficient, and tests performed for the city of Moscow and Novosibirsk region since 23.03.2020. In SEIR-HCD the population is divided into seven groups, and in SEIR-D into five groups with similar characteristics and transition probabilities depending on the specific region of interest. An identifiability analysis of SEIR-HCD is made to reveal the least sensitive unknown parameters as related to the additional information. The parameters are corrected by minimizing some objective functionals which is made by stochastic methods (simulated annealing, differential evolution, and genetic algorithm). Prognostic scenarios for COVID-19 spread in Moscow and in Novosibirsk region are developed, and the applicability of the models is analyzed.

In this paper, approaches to the numerical recovering of the initial condition in the inverse problem for a nonlinear singularly perturbed reaction–diffusion–advection equation are considered. The feature of the formulation of the inverse problem is the use of additional information about the value of the solution of the equation at the known position of a reaction front, measured experimentally with a delay relative to the initial moment of time. In this case, for the numerical solution of the inverse problem, the gradient method of minimizing the cost functional is applied. In the case when only the position of the reaction front is known, the method of deep machine learning is applied. Numerical experiments demonstrated the possibility of solving such kinds of considered inverse problems.

The article aimed to show the fundamental possibility of constructing a computational digital twin of the acoustic tomograph within the framework of a unified physics–mathematical model based on the Navier–Stokes equations. The authors suggested that the size of the modeling area is quite small, sound waves are waves of “small” disturbance, and given that a person consists of more than 60% water, human organs can be modeled using a liquid model, taking into account their density. During numerical experiments, we obtained the pressure registered in the receivers that are located on the side walls of the tomograph. The differences in pressure values are shown depending on the configuration of inclusions in the mannequin imitating internal organs. The results show that the developed technology can be used to probe the human body in medical acoustic tomographs and determine the acoustic parameters of the human body to detect neoplasms.