Dr. Marta Prado
Analytical Chemistry, Nutrition and Bormatology, University of Santiago de Compostela, Santiago de Compostela, Galicia, Spain
Distinguish Researcher (Beatriz Galindo Senior Grantee)
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Academic Career Length
25Years (2002-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 April 2006 in Food Research International
Journal Article
CCCarmen A. Campos
Carmen A. Campos
ÓRÓscar Rodríguez
Óscar Rodríguez
PCPilar Calo-Mata
Pilar Calo-Mata
Marta Prado
Jorge Barros-Velázquez7 April 2015 in Critical Reviews in Food Science and Nutrition
Journal Article
Marta PradoIOIgnacio Ortea
Ignacio OrteaSVS. Vial
S. Vial
José RivasPCP. Calo-Mata
P. Calo-Mata
Jorge Barros-VelázquezCurrently, food allergies are an important health concern worldwide. The presence of undeclared allergenic ingredients or the presence of traces of allergens due to contamination during food processing poses a great health risk to sensitized individuals. Therefore, reliable analytical methods are required to detect and identify allergenic ingredients in food products. The present review addresses the recent developments regarding the application of DNA- and protein-based methods for the detection of allergenic ingredients in foods. The fitness-for-purpose of reviewed methodology will be discussed, and future trends will be highlighted. Special attention will be given to the evaluation of the potential of newly developed and promising technologies that can improve the detection and identification of allergenic ingredients in foods, such as the use of biosensors and/or nanomaterials to improve detection limits, specificity, ease of use, or to reduce the time of analysis. Such rapid food allergen test methods are required to facilitate the reliable detection of allergenic ingredients by control laboratories, to give the food industry the means to easily determine whether its product has been subjected to cross-contamination and, simultaneously, to identify how and when this cross-contamination occurred.
Journal Article
ADAzza Dammak
Azza DammakCPCristina Pastrana
Cristina Pastrana
Alba Martín-GilCCCarlos Carpena-Torres
Carlos Carpena-TorresACAssumpta Peral Cerda
Assumpta Peral Cerda
juan gonzalo carracedo rodriguez +3
The eye is a metabolically active structure, constantly exposed to solar radiations making its structure vulnerable to the high burden of reactive oxygen species (ROS), presenting many molecular interactions. The biomolecular cascade modification is caused especially in diseases of the ocular surface, cornea, conjunctiva, uvea, and lens. In fact, the injury in the anterior segment of the eye takes its origin from the perturbation of the pro-oxidant/antioxidant balance and leads to increased oxidative damage, especially when the first line of antioxidant defence weakens with age. Furthermore, oxidative stress is related to mitochondrial dysfunction, DNA damage, lipid peroxidation, protein modification, apoptosis, and inflammation, which are involved in anterior ocular disease progression such as dry eye, keratoconus, uveitis, and cataract. The different pathologies are interconnected through various mechanisms such as inflammation, oxidative stress making the diagnostics more relevant in early stages. The end point of the molecular pathway is the release of different antioxidant biomarkers offering the potential of predictive diagnostics of the pathology. In this review, we have analysed the oxidative stress and inflammatory processes in the front of the eye to provide a better understanding of the pathomechanism, the importance of biomarkers for the diagnosis of eye diseases, and the recent treatment of anterior ocular diseases.
Journal Article
ADAzza Dammak
Azza DammakFHFernando Huete-Toral
Fernando Huete-ToralCCCarlos Carpena-Torres
Carlos Carpena-TorresAlba Martín-GilCPCristina Pastrana
Cristina Pastranajuan gonzalo carracedo rodriguezMost irreversible blindness observed with glaucoma and retina-related ocular diseases, including age-related macular degeneration and diabetic retinopathy, have their origin in the posterior segment of the eye, making their physiopathology both complex and interconnected. In addition to the age factor, these diseases share the same mechanism disorder based essentially on oxidative stress. In this context, the imbalance between the production of reactive oxygen species (ROS) mainly by mitochondria and their elimination by protective mechanisms leads to chronic inflammation. Oxidative stress and inflammation share a close pathophysiological process, appearing simultaneously and suggesting a relationship between both mechanisms. The biochemical end point of these two biological alarming systems is the release of different biomarkers that can be used in the diagnosis. Furthermore, oxidative stress, initiating in the vulnerable tissue of the posterior segment, is closely related to mitochondrial dysfunction, apoptosis, autophagy dysfunction, and inflammation, which are involved in each disease progression. In this review, we have analyzed (1) the oxidative stress and inflammatory processes in the back of the eye, (2) the importance of biomarkers, detected in systemic or ocular fluids, for the diagnosis of eye diseases based on recent studies, and (3) the treatment of posterior ocular diseases, based on long-term clinical studies.
1 August 2018 in Food Microbiology
Journal Article
AGAlejandro Garrido-Maestu
Alejandro Garrido-MaestuSASarah Azinheiro
Sarah AzinheiroJCJoana Carvalho
Joana CarvalhoMarta PradoJournal Article
Alejandro Martínez-ÁguilaAlba Martín-GilCCCarlos Carpena-Torres
Carlos Carpena-TorresCPCristina Pastrana
Cristina Pastranajuan gonzalo carracedo rodriguezCircadian rhythm and the molecules involved in it, such as melanopsin and melatonin, play an important role in the eye to regulate the homeostasis and even to treat some ocular conditions. As a result, many ocular pathologies like dry eye, corneal wound healing, cataracts, myopia, retinal diseases, and glaucoma are affected by this cycle. This review will summarize the current scientific literature about the influence of circadian patterns on the eye, focusing on its relationship with increased intraocular pressure (IOP) fluctuations and glaucoma. Regarding treatments, two ways should be studied: the first one, to analyze if some treatments could improve their effect on the ocular disease when their posology is established in function of circadian patterns, and the second one, to evaluate new drugs to treat eye pathologies related to the circadian rhythm, as it has been stated with melatonin or its analogs, that not only could be used as the main treatment but as coadjutant, improving the circadian pattern or its antioxidant and antiangiogenic properties.
About Me
Marta Prado got her advanced degree in Food Science and Technology in 1999 from the University of Santiago de Compostela (Spain). On 2005 she obtained her PhD from the same university in the program of Nutrition, Bromatology and Food technology.
Between 2006 and 2010, she has been working as Scientific Officer in the Food Safety and Quality Unit at the Institute of Reference Materials and Measurements from the Joint Research Centre of the European Commission (EC-JRC-IRMM) in Geel, Belgium.
During the last years she has been working on the development of real-time PCR methods for their application in food and environmental analysis, in particular to ensure the quality and authenticity of food products in the food chain. She has been working on the evaluation of the fitness-for-purpose of such methods, including transferability between laboratories, and their quantification potential. From November 2010 until September 2023 she worked at the International Iberian Nanotechnology Laboratory (INL), where she led the Food Quality and Safety Research Group (FQ&S) on the development of new, fast and reliable detection methodologies combining molecular biology and nanotechnology, the development and application of microfluidic platforms for bioanalysis and the application of biosensors as a tool to ensure safety and quality along the food chain.
From October 2023, she works at the University of Santiago de Compostela as Distinguish Researcher with a Beatriz Galindo Senior Grant
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