Alessio Zanza

Dr. Alessio Zanza

University of Rome La Sapienza
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 December 2021 in Bioengineering
Verified
Journal Article
Open access
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Alessio ZanzaAlessio Zanza
Alessio Zanza
MDMaurilio D'angelo
Maurilio D'angelo
Rodolfo RedaRodolfo Reda
Rodolfo Reda
Gianluca GambariniGianluca Gambarini
Gianluca Gambarini
Luca TestarelliLuca Testarelli
Luca Testarelli
Dario Di NardoDario Di Nardo
Dario Di Nardo
Since the introduction of Nickel-Titanium alloy as the material of choice for the manufacturing of endodontic rotary instruments, the success rate of the root canal therapies has been significantly increased. This success mainly arises from the properties of the Nickel-Titanium alloy: the biocompatibility, the superelasticity and the shape memory effect. Those characteristics have led to a reduction in time of endodontic treatments, a simplification of instrumentation procedures and an increase of predictability and effectiveness of endodontic treatments. Nevertheless, the intracanal separation of Nickel-Titanium rotary instruments is still a major concern of endodontists, with a consequent possible reduction in the outcome rate. As thoroughly demonstrated, the two main causes of intracanal separation of endodontic instruments are the cyclic fatigue and the torsional loads. As results, in order to reduce the percentage of intracanal separation research and manufacturers have been focused on the parameters that directly or indirectly influence mechanical properties of endodontic rotary instruments. This review describes the current state of the art regarding the Nickel-Titanium alloy in endodontics, the mechanical behavior of endodontic rotary instruments and the relative stresses acting on them during intracanal instrumentation, highlighting the limitation of the current literature.

31 May 2021 in Diagnostics
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Journal Article
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Sanjeev KhanagarSanjeev Khanagar
Sanjeev Khanagar
SNSACHIN NAIK
SACHIN NAIK
AKAbdul Aziz Abdullah Al Kheraif
Abdul Aziz Abdullah Al Kheraif
SVsatish vishwanathaiah
satish vishwanathaiah
PMPrabhadevi Maganur
Prabhadevi Maganur
Shankargouda PatilShankargouda Patil
Shankargouda Patil
Oral cancer (OC) is a deadly disease with a high mortality and complex etiology. Artificial intelligence (AI) is one of the outstanding innovations in technology used in dental science. This paper intends to report on the application and performance of AI in diagnosis and predicting the occurrence of OC. In this study, we carried out data search through an electronic search in several renowned databases, which mainly included PubMed, Google Scholar, Scopus, Embase, Cochrane, Web of Science, and the Saudi Digital Library for articles that were published between January 2000 to March 2021. We included 16 articles that met the eligibility criteria and were critically analyzed using QUADAS-2. AI can precisely analyze an enormous dataset of images (fluorescent, hyperspectral, cytology, CT images, etc.) to diagnose OC. AI can accurately predict the occurrence of OC, as compared to conventional methods, by analyzing predisposing factors like age, gender, tobacco habits, and bio-markers. The precision and accuracy of AI in diagnosis as well as predicting the occurrence are higher than the current, existing clinical strategies, as well as conventional statistics like cox regression analysis and logistic regression.

21 April 2021 in Journal of Imaging
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Journal Article
Open access
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Rodolfo RedaRodolfo Reda
Rodolfo Reda
Alessio ZanzaAlessio Zanza
Alessio Zanza
AMAlessandro Mazzoni
Alessandro Mazzoni
ACAndrea Cicconetti
Andrea Cicconetti
Luca TestarelliLuca Testarelli
Luca Testarelli
Dario Di NardoDario Di Nardo
Dario Di Nardo
This narrative review aims to evaluate the current evidence for the application of magnetic resonance imaging (MRI), a radiation-free diagnostic exam, in some fields of dentistry. Background: Radiographic imaging plays a significant role in current first and second level dental diagnostics and treatment planning. However, the main disadvantage is the high exposure to ionizing radiation for patients. Methods: A search for articles on dental MRI was performed using the PubMed electronic database, and 37 studies were included. Only some articles about endodontics, conservative dentistry, implantology, and oral and craniofacial surgery that best represented the aim of this study were selected. Results: All the included articles showed that MRI can obtain well-defined images, which can be applied in operative dentistry. Conclusions: This review highlights the potential of MRI for diagnosis in dental clinical practice, without the risk of biological damage from continuous ionizing radiation exposure.

14 November 2021 in Journal of Imaging
Verified
Journal Article
Open access
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Rodolfo RedaRodolfo Reda
Rodolfo Reda
Alessio ZanzaAlessio Zanza
Alessio Zanza
ACAndrea Cicconetti
Andrea Cicconetti
SBShilpa Bhandi
Shilpa Bhandi
GMGabriele Miccoli
Gabriele Miccoli
Dario Di NardoDario Di Nardo
Dario Di Nardo
(1) Background: the frequency with which diagnostic tests are prescribed with exposure to ionizing radiation, a cause of biological damage, has been studied, and with much more attention, patients are subjected to these diagnostic tests for diagnosis and follow-up. This review aimed, given the recent developments of this technology, to evaluate the possible use of ultrasound in different branches of dentistry. The possibility of applying ionizing-radiation-free diagnostic exams in dentistry, overcoming the limits of this application, has led scientific research in this area to obtain interesting results that bode well for the future. (2) Methods: a search for articles on the application of ultrasounds in dentistry was performed using the PubMed electronic database. (3) Results: only 32 studies were included, and these clearly stated that this examination is widely usable and in great progress. (4) Conclusions: regarding the modern application techniques of this diagnostic test, it is essential to consider technological evolution as an objective to reduce the damage and side effects of necessary diagnostic tests. The use of ultrasound in dentistry can represent a valid radiation-free alternative, in certain contexts, to the other most used exams.

1 July 2021 in Journal of Endodontics
Verified
Journal Article
Closed access
Alessio ZanzaAlessio Zanza
Alessio Zanza
MSMarco Seracchiani
Marco Seracchiani
Dario Di NardoDario Di Nardo
Dario Di Nardo
RRRodolfo Reda
Rodolfo Reda
GGGianluca Gambarini
Gianluca Gambarini
LTLuca Testarelli
Luca Testarelli

17 January 2022 in Methods and Protocols
Verified
Journal Article
Open access
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Rodolfo RedaRodolfo Reda
Rodolfo Reda
Alessio ZanzaAlessio Zanza
Alessio Zanza
ACAndrea Cicconetti
Andrea Cicconetti
SBShilpa Bhandi
Shilpa Bhandi
RGRenzo Guarnieri
Renzo Guarnieri
Dario Di NardoDario Di Nardo
Dario Di Nardo
Background: The most used types of retention of implant-supported prostheses are screw-retained or cement-retained restorations. The advantages and disadvantages of both have been identified by various authors over the years. However, cement-retained implant crowns and fixed partial dentures are among the most used types of restorations in implant prostheses, due to their aesthetic and clinical advantages. When cemented prostheses are made on implants, the problem of cement residues is important and often associated with biological implant pathologies. The objective of this research was to establish to what extent the techniques to reduce excess cement really affect the volume of cement residues. Materials and Methods: This review was written following the PRISMA statement; a detailed search was carried out in three different electronic databases—PubMed, Scopus, and Cochrane Library. The inclusion criteria were prospective clinical studies, with at least 10 participants per group, and with at least 6 months of the follow-up period. Results: There have been many proposals for techniques supposed to reduce the amount of excess cement in the peri-implant sulcus and on the prosthetic components, but of these, which are exceptional in their in vitro capabilities, very few have been clinically validated, and this represents the real limitation and a great lack of knowledge regarding this topic. Three articles met the inclusion criteria, which were analyzed and compared, to obtain the information necessary for the purposes of the systematic review. Discussion: Extraoral cementation can reduce the excess cement, which, after a normal excess removal procedure, is, nevertheless, of such size that it does not affect the possibility of peri-implant pathologies developing. All these studies concluded that a small amount of cement residue is found in the gingival sulcus, and using eugenol-free oxide cements, the residues were only deposited on the metal surfaces, with a better peri-implant tissues health. Conclusion: Despite the limitations of this study, it was possible to carefully analyze these characteristics and obtain valuable suggestions for daily clinical practice. Resinous cements are considered, due to the free monomers present in them, toxic for the soft tissues. The provisional zinc-oxide cements, also eugenol-free, represent the ideal choice. The different grades of retentive forces provided by these cements do not seem to have clinical effects on the decementation of restorations.