Human action recognition has emerged as a challenging research domain for video understanding and analysis. Subsequently, extensive research has been conducted to achieve the improved performance for recognition of human actions. Human activity recognition has various real time applications, such as patient monitoring in which patients are being monitored among a group of normal people and then identified based on their abnormal activities. Our goal is to render a multi class abnormal action detection in individuals as well as in groups from video sequences to differentiate multiple abnormal human actions. In this paper, You Look only Once (YOLO) network is utilized as a backbone CNN model. For training the CNN model, we constructed a large dataset of patient videos by labeling each frame with a set of patient actions and the patient’s positions. We retrained the back-bone CNN model with 23,040 labeled images of patient’s actions for 32 epochs. Across each frame, the proposed model allocated a unique confidence score and action label for video sequences by finding the recurrent action label. The present study shows that the accuracy of abnormal action recognition is 96.8%. Our proposed approach differentiated abnormal actions with improved F1-Score of 89.2% which is higher than state-of-the-art techniques. The results indicate that the proposed framework can be beneficial to hospitals and elder care homes for patient monitoring.