Brain tumors have become a leading cause of death around the globe. The main reason for this epidemic is the difficulty conducting a timely diagnosis of the tumor. Fortunately, magnetic resonance images (MRI) are utilized to diagnose tumors in most cases. The performance of a Convolutional Neural Network (CNN) depends on many factors (i.e., weight initialization, optimization, batches and epochs, learning rate, activation function, loss function, and network topology), data quality, and specific combinations of these model attributes. When we deal with a segmentation or classification problem, utilizing a single optimizer is considered weak testing or validity unless the decision of the selection of an optimizer is backed up by a strong argument. Therefore, optimizer selection processes are considered important to validate the usage of a single optimizer in order to attain these decision problems. In this paper, we provides a comprehensive comparative analysis of popular optimizers of CNN to benchmark the segmentation for improvement. In detail, we perform a comparative analysis of 10 different state-of-the-art gradient descent-based optimizers, namely Adaptive Gradient (Adagrad), Adaptive Delta (AdaDelta), Stochastic Gradient Descent (SGD), Adaptive Momentum (Adam), Cyclic Learning Rate (CLR), Adaptive Max Pooling (Adamax), Root Mean Square Propagation (RMS Prop), Nesterov Adaptive Momentum (Nadam), and Nesterov accelerated gradient (NAG) for CNN. The experiments were performed on the BraTS2015 data set. The Adam optimizer had the best accuracy of 99.2% in enhancing the CNN ability in classification and segmentation.

Image reconstruction in magnetic resonance imaging (MRI) and computed tomography (CT) is a mathematical process that generates images at many different angles around the patient. Image reconstruction has a fundamental impact on image quality. In recent years, the literature has focused on deep learning and its applications in medical imaging, particularly image reconstruction. Due to the performance of deep learning models in a wide variety of vision applications, a considerable amount of work has recently been carried out using image reconstruction in medical images. MRI and CT appear as the ultimate scientifically appropriate imaging mode for identifying and diagnosing different diseases in this ascension age of technology. This study demonstrates a number of deep learning image reconstruction approaches and a comprehensive review of the most widely used different databases. We also give the challenges and promising future directions for medical image reconstruction.

Diffuse optical tomography (DOT) has shown a great potential for breast imaging^{1 – 9} and functional brain imaging,^{10 – 12} which use near-infrared light in the spectral range of 600 to 950 nm to quantify tissue optical (absorption and scattering) coefficients. There is a critical need to develop an efficient image reconstruction algorithm for DOT. Recovering the internal distribution of optical properties is a severely ill-posed and under-determined inverse problem, due to light propagation in highly scattering biological tissues and limited number of measurements,^13,14 which makes image reconstruction challenging.

A number of resources, every year, being spent to tackle early detection of cardiac abnormalities which is one of the leading causes of deaths all over the Globe. The challenges for healthcare systems includes early detection, portability and mobility of patients. This paper presents a categorical review of smartphone-based systems that can detect cardiac abnormalities by the analysis of Electrocardiogram (ECG) and Photoplethysmography (PPG) and the limitation and challenges of these system. The ECG based systems can monitor, record and forward signals for analysis and an alarm can be triggered in case of abnormality, however the limitation of smart phone’s processing capabilities, lack of storage and speed of network are major challenges. The systems based on PPG signals are non-invasive and provides mobility and portability. This study aims to critically review the existing systems, their limitation, challenges and possible improvements to serve as a reference for researchers and developers.

The developed framework apportions model error to inputs, computes predictive guarantees, and enables model correctability.