Andrea Maria Chisnoiu

Dr. Andrea Maria Chisnoiu

"Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania
orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 September 2015 in Medicine and Pharmacy Reports
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Andrea Maria ChisnoiuAndrea Maria Chisnoiu
Andrea Maria Chisnoiu
APAlina Monica Picos
Alina Monica Picos
SPSever Popa
Sever Popa
PCPetre Daniel Chisnoiu
Petre Daniel Chisnoiu
LLLiana Lascu
Liana Lascu
RCRadu Chisnoiu
Radu Chisnoiu
Background and aim. This review aims at presenting a current view on the most frequent factors involved in the mechanisms causing temporomandibular disorders (TMD).Method. We conducted a critical review of the literature for the period January 2000 to December 2014 to identify factors related to TMD development and persistence.Results. The etiology of TMD is multidimensional: biomechanical, neuromuscular, bio-psychosocial and biological factors may contribute to the disorder. Occlusal overloading and parafunctions (bruxism) are frequently involved as biomechanical factors; increased levels of estrogen hormones are considered biological factors affecting the temporo-mandibular-joint. Among bio-psychosocial factors, stress, anxiety or depression, were frequently encountered.Conclusions. The etiopathogenesis of this condition is poorly understood, therefore TMDs are difficult to diagnose and manage. Early and correct identification of the possible etiologic factors will enable the appropriate treatment scheme application in order to reduce or eliminate TMDs debilitating signs and symptoms.

16 December 2021 in Polymers
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CODRUTA SAROSICODRUTA SAROSI
CODRUTA SAROSI
MMMarioara Moldovan
Marioara Moldovan
Andrada SoancaAndrada Soanca
Andrada Soanca
Ruxandra-Mioara RajnoveanuRuxandra-Mioara Rajnoveanu
Ruxandra-Mioara Rajnoveanu
TGTimea Gherman
Timea Gherman
Radu Marcel ChisnoiuRadu Marcel Chisnoiu
Radu Marcel Chisnoiu
(1) Background: This study investigated the influence of Bis-GMA, TEGDMA, UDMA, and two different polyethylene glycol (PEG)-containing, UDMO-based co-monomers on the Young’s modulus and flexural strength, degree of methacrylate C=C double bond conversion and residual monomer elution of experimental dental resins. (2) Methods: Urethane methacrylate-based monomer was synthesised via a radical chain growth polymerization mechanism using PEG in order to improve the mechanical properties. Dental resins were formulated using Bis-GMA, UDMA, or UDMO as base monomers combined with TEGDMA as a dilution monomer and DMAEM + CQ as the photo-initiator system. Degree of conversion (DC), mechanical properties, and residual monomer content of light-activated methacrylate resin formulations were evaluated and statistically analysed by ANOVA and a Tukey’s test. (3) Results: PEG-containing UDMO resins had lower Young’s modulus and elastic strength than UDMA-derived resin for all irradiation times. The highest DC (67,418%) was observed for the PEG-containing UDMO-based resin formulation when light cured for 40 s. For all samples, DC increased with the photo-polymerization time. The amount of residual monomer decreased after increasing the light-curing period from 20 to 40 s, resin with UDMO content 0.01 mol of PEG having the smallest amount of free eluted monomer. (4) Conclusions: A strong structure–property relationship exists in photo-cured dimethacrylate-based dental resins. The time and quantity of the photochemical initiation system can influence the physical–mechanical properties of the resins but also the monomers in their composition.

8 December 2023 in Medicina
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MMManuela Maria Manziuc
Manuela Maria Manziuc
Andreea KuiAndreea Kui
Andreea Kui
Andrea Maria ChisnoiuAndrea Maria Chisnoiu
Andrea Maria Chisnoiu
ALAnca Labunet
Anca Labunet
MNMarius Negucioiu
Marius Negucioiu
Smaranda BuduruSmaranda Buduru
Smaranda Buduru
Zirconia-reinforced lithium silicate (ZLS) ceramic is a new innovative dental material with unique a chemical composition that is designed to combine harmoniously with the appropriate optical properties of lithium disilicate and the enhanced mechanical strength of zirconia. A thorough understanding of ZLS materials is essential for both clinicians and dental technicians. At present, the mechanical behavior and optical properties of the ZLS ceramic system have not been extensively researched, and there is still a lack of consensus regarding the fabrication process and clinical behavior of ZLS all-ceramic restorations. The aim of the present study was to present a selection of comprehensive information concerning zirconia-reinforced lithium silicate ceramics and their optical and mechanical properties, as well as to assess data regarding cementation procedures and clinical outcomes for ZLS all-ceramic restorations. Three electronic databases (PubMed, Web of Science, and the Cochrane Library) were used for the research by two independent reviewers. The search was limited to articles published in the English language, as well as clinical and in vitro studies of color and studies on mechanical behavior and the cementation procedures of ZLS restorations. The exclusion criteria comprised abstracts, questionnaire-based studies, case reports, literature reviews, and studies that were not available in English. Zirconia-reinforced lithium-silicate-based ceramic presents a unique and complex microstructure that increases mechanical resistance but decreases aesthetic appearance, especially its translucency, due to tetragonal zirconia content. A material’s thickness, the color of the underlying tooth structure, and the resin cement shade are important factors that influence the final shade and aesthetic appearance of ZLS restorations. Mechanical properties, which are defined by the fracture toughness, flexural strength, elastic modulus, and hardness of ZLS ceramic are higher compared to feldspathic, lithium disilicate, and hybrid ceramics, as well as resin nanoceramics; however, they are lower than translucent or high-translucency zirconia. Acid etching, sandblasting, and laser etching represent the most used methods to prepare the ZLS restoration surfaces for proper bonding procedures.

Radu Marcel ChisnoiuRadu Marcel Chisnoiu
Radu Marcel Chisnoiu
Ada Gabriela DeleanAda Gabriela Delean
Ada Gabriela Delean
Alexandrina MunteanAlexandrina Muntean
Alexandrina Muntean
DRDoina Iulia Rotaru
Doina Iulia Rotaru
Andrea Maria ChisnoiuAndrea Maria Chisnoiu
Andrea Maria Chisnoiu
SCSanda Ileana Cimpean
Sanda Ileana Cimpean
The intent of the KAP (knowledge, attitude, practices) survey is to collect information about a specific target group related to their knowledge, what they consider to be known, and what they do about a particular topic. The aim of this study was to identify the level of importance of oral health, especially the level of knowledge, attitude and practices of rural patients around Cluj-Napoca, Romania. Material and methods: A questionnaire consisting of five parts was used, trying to assess the self-perception of oral health, knowledge and attitude towards oral health, dental hygiene practices and eating habits. A clinical examination was also performed in order to identify the number of missing teeth, the caries and the presence of calculus. Results: The study revealed that most patients have an average and good self-perception of oral health, although three-quarters of them have calculus deposits, and about half of them have more than three carious lesions and at least one extracted tooth. There is also a discrepancy between declared knowledge of oral health, eating habits and dental practices. Conclusions: The basic knowledge of rural patients about oral health can be considered satisfactory, but the practices, unfortunately, do not reflect this knowledge.

22 November 2023 in Biomedicines
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Andreea KuiAndreea Kui
Andreea Kui
MMManuela Maria Manziuc
Manuela Maria Manziuc
ȘPȘtefan Adrian Petruțiu
Ștefan Adrian Petruțiu
Smaranda BuduruSmaranda Buduru
Smaranda Buduru
ALAnca Labunet
Anca Labunet
Andrea Maria ChisnoiuAndrea Maria Chisnoiu
Andrea Maria Chisnoiu
Over the past two decades, dental ceramics have experienced rapid advances in science and technology, becoming the fastest-growing field of dental materials. This review emphasizes the significant impact of translucent zirconia in fixed prosthodontics, merging aesthetics with strength, and highlights its versatility from single crowns to complex bridgework facilitated by digital manufacturing advancements. The unique light-conducting properties of translucent zirconia offer a natural dental appearance, though with considerations regarding strength trade-offs compared to its traditional, opaque counterpart. The analysis extends to the mechanical attributes of the material, noting its commendable fracture resistance and durability, even under simulated physiological conditions. Various zirconia types (3Y-TZP, 4Y-TZP, 5Y-TZP) display a range of strengths influenced by factors like yttria content and manufacturing processes. The study also explores adhesive strategies, underlining the importance of surface treatments and modern adhesives in achieving long-lasting bonds. In the realm of implant-supported restorations, translucent zirconia stands out for its precision, reliability, and aesthetic adaptability, proving suitable for comprehensive dental restorations. Despite its established benefits, the review calls for ongoing research to further refine the material’s properties and adhesive protocols and to solidify its applicability through long-term clinical evaluations, ensuring its sustainable future in dental restorative applications.

22 January 2024 in Biomedicines
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MPMihaela Pastrav
Mihaela Pastrav
OPOvidiu Pastrav
Ovidiu Pastrav
Andrea Maria ChisnoiuAndrea Maria Chisnoiu
Andrea Maria Chisnoiu
Radu Marcel ChisnoiuRadu Marcel Chisnoiu
Radu Marcel Chisnoiu
SCStanca Cuc
Stanca Cuc
DFDana Festila
Dana Festila
(1) Background: the current study investigated three nanohybrid composites: two commercial products ClearfilMajestyTM (CM) and HarmonizeTM (HU), compared with an experimental product PS2. (2) Methods: Two sample types were molded using Teflon dies. The first sample type was represented by standard discs (20 mm diameter and 2 mm thickness) (n = 60, 20/each material), used for surface conditioning investigation, specifically roughness monitoring and color stability analysis using AFM and the CIELab test, respectively. The second sample type was a standard cylindrical specimen (4 mm diameter and 6 mm height) for compression testing (n = 60, 20/each material). After complete polymerization, the samples were ground with sandpaper and further polished. The filler size and distribution in the polymer matrix were investigated with SEM. Data were statistically analyzed using the Anova Test followed by Tukey’s post hoc test on the Origin Lab 2019 software produced by OriginLab Corporation, Northampton, MA, USA. (3) Results: A mono-disperse system was identified in HU samples, while CM and PS2 revealed both nano- and microfiller particles. The samples’ observation after immersion in coffee and tea indicated that a lower roughness combined with optimal filler lamination within the polymer matrix assured the best color preservation. The compression strength was lower for the HU sample, while higher values were obtained for the complex filler systems within CM and PS2. (4) Conclusions: the behavior of the investigated nanohybrid composites strongly depends on the microstructural features.