An atlas of 98 microgrippers that recently appeared in Literature is herein presented by using four different forms: (a) a restyled layout of the original mechanical structure, (b) its corresponding pseudorigid body model (PRBM), (c) its kinematic chain, and finally, (d) its related graph. Homogeneity in functional sketching (a) is assumed to be greatly helpful to understand how these grippers work and what are the most significant differences between them. Therefore, a unified and systematic set of aesthetics and proportionality criteria have been adopted. Analogously, unified criteria for obtaining pseudorigid (b), kinematic (c), and graph (d) representations have been also used, which made the atlas easy to be read and inspected. The distinction among lumped and distributed compliance has been also accepted to develop the structure of the atlas. A companion paper has been prepared to present a survey on the variety of operational strategies that are used in these microgrippers.

This article provides an overview of the operational strategies adopted in microgrippers design. The review covers microgrippers recently proposed in Literature, some of which have been systematically presented in a companion paper, where their topological, kinematic, and structural characteristics are discussed. In the present contribution, the prevalent actuation methods and the operational aspects are discussed: the tip displacement, the tip force, the actuation voltage, and the amplification factor are the reference parameters that are adopted to compare the different types of actuation and operational strategies. In addition, the control strategies and control algorithms currently adopted are reviewed.

Although tissue and cell manipulation nowadays is a common task in biomedical analysis, there are still many different ways to accomplish it, most of which are still not sufficiently general, inexpensive, accurate, efficient or effective. Several problems arise both for in vivo or in vitro analysis, such as the maximum overall size of the device and the gripper jaws (like in minimally-invasive open biopsy) or very limited manipulating capability, degrees of freedom or dexterity (like in tissues or cell-handling operations). This paper presents a new approach to tissue and cell manipulation, which employs a conceptually new conjugate surfaces flexure hinge (CSFH) silicon MEMS-based technology micro-gripper that solves most of the above-mentioned problems. The article describes all of the phases of the development, including topology conception, structural design, simulation, construction, actuation testing and in vitro observation. The latter phase deals with the assessment of the function capability, which consists of taking a series of in vitro images by optical microscopy. They offer a direct morphological comparison between the gripper and a variety of tissues.

This paper presents a new concept flexure hinge for MEMS applications and reveals how to design, construct, and experimentally test. This hinge combines a curved beam, as a flexible element, and a pair of conjugate surfaces, whose contact depends on load conditions. The geometry is conceived in such a way that minimum stress conditions are maintained within the flexible beam. A comparison of the new design with the other kind of revolute and flexible joints is presented. Then, the static behavior of the hinge is analyzed by means of a theoretical approach, based on continuum mechanics, and the results are compared to those obtained by means of finite element analysis (FEA) simulation. A silicon hinge prototype is also presented and the construction process, based on single step lithography and reactive ion etching (RIE) technology, is discussed. Finally, a crucial in–SEM experiment is performed and the experimental results are interpreted through the theoretical models.

In the last decades, grippers have been employed extensively at the microscale, for example, in microbiology and in microassembly. In these fields, specifically, it is essential to improve the performance of these systems in terms of precision, actuation, and sensing of the gripping force. Recent investigations drew attention on the tip–environment interaction force, which gave rise to further studies on the tip compliance behavior. This paper reveals a new method for designing MEMS technology-based compliant microgrippers with prescribed specifications for the jaw tip compliance. This approach relies on the equivalence between a compliant mechanism and its corresponding pseudorigid-body model (PRBM), the former embedding conjugate surfaces flexure hinges (CSFHs) as flexures. Such correspondence has been assessed by means of finite element analysis (FEA) simulations and theoretical models.