Point-of-care devices can analyze or characterize a sample in a short period of time. New technologies in medical science seek integrations of different measurement techniques for a complete analysis. This study describes the fabrication method, tests, and results of microtechnology as an approach for an integrated rheometer. The portable device measured the average flow velocity to calculate its viscosity. The whole system encompasses a microdevice integrated to a data acquisition system powered by USB and controlled by a full custom software. As a result, we obtained an easy-to-handle and fabricate hand-held microrheometer. The device was tested using Newtonian fluids such as Mili-Q water, aqueous solution of Ethylene-glycol at 40% and 25% and Non-Newtonian blood samples. The whole device can provide the non-linear viscosity of a 0.08ml blood sample in less than 30 seconds, in a wide range of shear rate with an accuracy of 93%. More importantly, due to its detection method and simplicity, it can be enclosed within almost any fluidic microsystem, including biomedical applications.
We present a small, compact and portable envisaged lab-on-a-chip (LoC) device for point-of-care (PoC) detection of different key parameters on diabetes mellitus analysis; glucose, cholesterol, triglycerides and hematocrit. These four parameters, present in blood samples, are important in the standardized analysis affecting different patients with different medical conditions. The quantification of glucose, cholesterol, triglycerides and hematocrit it is performed with a single disposable device using a single blood drop, enhancing disposition decision time and improving patient satisfaction when compared with actual analytical methodology, and it is an easy to use device and no skilled personnel is needed to use it, avoiding the use of more complicated processes like phlebotomy. The presented device consists of a custom sensing system, low power electronic instrumentation and an easy user interpretation readout display, powered by a single battery.
Wearable sweat‐sensing technologies offer a non‐invasive and patient‐friendly route toward near‐patient diagnostics, yet their development is hindered by the lack of realistic test platforms that reproduce human perspiration dynamics. Artificial skin phantoms capable of mimicking physiological sweat generation could substantially reduce development time and reliance on human testing. Here, a 3D multilayer artificial skin phantom is introduced that emulates eccrine sweat glands through stacked Flexdym microchannels with tunable poly(vinyl alcohol)–induced wettability contrast. The platform combines soft lithography, thermal imprinting, and surface treatments to replicate pore geometry and to precisely control hydraulic resistance (≈2.62 × 10 15 Pa s m −3 ). The system further reproduces pulsatile flow rates of approximately 3 nL min −1 per pore, closely matching reported physiological eccrine sweat secretion. The resulting skin phantom enables scalable and reproducible simulation of low‐rate perspiration and overcomes limitations of existing membrane‐based or static microchannel models. This platform provides a versatile preclinical testbed for the evaluation of wearable sweat sensors, transdermal delivery patches, skin‐adherent materials, and cosmetic or therapeutic formulations. Future integration of embedded sensing elements and localized flow control is expected to support real‐time diagnostic assessment and transdermal testing under dynamic conditions.