Jakub Vlček

Dr. Jakub Vlček

orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2018 in Composites Part B: Engineering
Verified
Journal Article
Closed access
LLLubomir Lapcik
Lubomir Lapcik
DMDavid Maňas
David Maňas
BLBarbora Lapčíková
Barbora Lapčíková
Martin VašinaMartin Vašina
Martin Vašina
MSMichal Stanek
Michal Stanek
NRNeil A. Rowson
Neil A. Rowson

1 December 2016 in Composites Part B: Engineering
Verified
Journal Article
Open access
LLLubomir Lapcik
Lubomir Lapcik
MRMatthew J.A. Ruszala
Matthew J.A. Ruszala
Martin VašinaMartin Vašina
Martin Vašina
BLBarbora Lapčíková
Barbora Lapčíková
JVJakub Vlček
Jakub Vlček
RGRichard W. Greenwood
Richard W. Greenwood
There were studied four types of powder filler materials for polyolefin composite parts production for automotive and aerospace industry. There was confirmed, that the particle shape has a strong effect on the acoustic and mechanical properties of the powder bed as influenced by the varying packing density. The calcium carbonate spherical hollow particles exhibited the best aerodynamic performance when aerated and were completely fluidised. Simultaneously they were exhibiting the easy flowing behaviour as reflected in the observed flowability of 4.71. In contrary to this, the flat lamellar geometry of the precipitated calcium carbonate resulted in the worst fluidisation behaviour, as the aeration energy was 2.5x higher in comparison to the spherical particles. Remaining samples under study, i.e. flash calcined kaolin and dolomite powder, exhibited cohesive rheological behaviour as reflected in the observed flowability. There was found a clear correlation between powder rheological and electrostatic charge data with the observed acoustic performance as reflected in the frequency dependence of the normal incident sound damping coefficient. This was demonstrated by a relatively high increase in the damping efficiency with increasing porosity of the powder bed as reflected in the decreasing packing density. However the best fit was found between the absolute value of the electrostatic charge values and the sound damping properties.Web of Science106807

1 May 2015 in Food Chemistry
Verified
Journal Article
Closed access
LLLubomir Lapcik
Lubomir Lapcik
BLBarbora Lapčíková
Barbora Lapčíková
EOEva Otyepková
Eva Otyepková
Michal OtyepkaMichal Otyepka
Michal Otyepka
JVJakub Vlček
Jakub Vlček
Richardos Nikolaos SalekRichardos Nikolaos Salek
Richardos Nikolaos Salek

8 April 2022 in Pharmaceutics
Verified
Journal Article
Open access
PDF file
KKKlára Kostelanská
Klára Kostelanská
BPBarbora Blahova Prudilova
Barbora Blahova Prudilova
Sylva HolešováSylva Holešová
Sylva Holešová
JVJakub Vlček
Jakub Vlček
DVDavid Vetchý
David Vetchý
JGJan Gajdziok
Jan Gajdziok
High specific surface area (SSA), porous structure, and suitable technological characteristics (flow, compressibility) predetermine powder carriers to be used in pharmaceutical technology, especially in the formulation of liquisolid systems (LSS) and solid self-emulsifying delivery systems (s-SEDDS). Besides widely used microcrystalline cellulose, other promising materials include magnesium aluminometasilicates, mesoporous silicates, and silica aerogels. Clay minerals with laminar or fibrous internal structures also provide suitable properties for liquid drug incorporation. This work aimed at a comparison of 14 carriers’ main properties. Cellulose derivatives, silica, silicates, and clay minerals were evaluated for flow properties, shear cell experiments, SSA, hygroscopicity, pH, particle size, and SEM. The most promising materials were magnesium aluminometasilicates, specifically Neusilin® US2, due to its proper flow, large SSA, etc. Innovative materials such as FujiSil® or Syloid® XDP 3050 were for their properties evaluated as suitable. The obtained data can help choose a suitable carrier for formulations where the liquid phase is incorporated into the solid dosage form. All measurements were conducted by the same methodology and under the same conditions, allowing a seamless comparison of property evaluation between carriers, for which available company or scientific sources do not qualify due to different measurements, conditions, instrumentation, etc.

1 November 2014 in International Journal of Heat and Mass Transfer
Verified
Journal Article
Closed access
JVJakub Vlček
Jakub Vlček
LLLubomir Lapcik
Lubomir Lapcik
JČJiří Čech
Jiří Čech
BLBarbora Lapčíková
Barbora Lapčíková