In recent years, thanks to the development of additive manufacturing techniques, pros-thetic surgery has reached increasingly cutting-edge levels, revolutionizing the clinical course of patients suffering from joint arthritis, rheumatoid arthritis, post-traumatic arthrosis, etc. This work aims to evaluate the best materials for prosthetic surgery in hip implants from a tribological and mechanical point of view by using a machine-learning algorithm coupling with multi-body modeling and Finite Element Method (FEM) simulations. The innovative aspect is represented by the use of machine learning for the creation of a humanoid model in a multibody software environment that aimed to evaluate the load and rotation condition at the hip joint. After the boundary conditions have been defined, a Finite Element (FE) model of the hip implant has been created. The material properties and the information on the tribological behavior of the material couplings under investigation have been obtained from literature studies. The wear process has been investigated through the implementation of the Archard’s wear law in the FE model. The results of the FE simulation show that the best wear behavior has been obtained by CoCr alloy/UHMWPE coupling with a volume loss due to a wear of 0.004 ${\mathsf{\mu }\mathrm{m}}^3$ at the end of the simulation of ten sitting cycles. After the best pairs in terms of wear has been established, a topology optimization of the whole hip implant structure has been performed. The results show that, after the optimization process, it was possible to reduce implant mass making the implant 28.12% more lightweight with respect to the original one.

This study examined the efficacy of an optimized DeepLabCut (DLC) model in motion capture, with a particular focus on the sit-to-stand (STS) movement, which is crucial for assessing the functional capacity in elderly and postoperative patients. This research uniquely compared the performance of this optimized DLC model, which was trained using ’filtered’ estimates from the widely used OpenPose (OP) model, thereby emphasizing computational effectiveness, motion-tracking precision, and enhanced stability in data capture. Utilizing a combination of smartphone-captured videos and specifically curated datasets, our methodological approach included data preparation, keypoint annotation, and extensive model training, with an emphasis on the flow of the optimized model. The findings demonstrate the superiority of the optimized DLC model in various aspects. It exhibited not only higher computational efficiency, with reduced processing times, but also greater precision and consistency in motion tracking thanks to the stability brought about by the meticulous selection of the OP data. This precision is vital for developing accurate biomechanical models for clinical interventions. Moreover, this study revealed that the optimized DLC maintained higher average confidence levels across datasets, indicating more reliable and accurate detection capabilities compared with standalone OP. The clinical relevance of these findings is profound. The optimized DLC model’s efficiency and enhanced point estimation stability make it an invaluable tool in rehabilitation monitoring and patient assessments, potentially streamlining clinical workflows. This study suggests future research directions, including integrating the optimized DLC model with virtual reality environments for enhanced patient engagement and leveraging its improved data quality for predictive analytics in healthcare. Overall, the optimized DLC model emerged as a transformative tool for biomechanical analysis and physical rehabilitation, promising to enhance the quality of patient care and healthcare delivery efficiency.

The field of additive manufacturing, particularly 3D printing, has ushered in a significant transformation in the realm of joint arthritis treatment through prosthetic surgery. This innovative technology allows for the creation of bespoke prosthetic devices that are tailored to meet the specific needs of individual patients. These devices are constructed using high-performance materials, including titanium and cobalt-chrome alloys. Nevertheless, the routine physical activities of patients, such as walking, sitting, and running, can induce wear and tear on the materials comprising these prosthetic devices, subsequently diminishing their functionality and durability. In response to this challenge, this research has endeavored to leverage novel techniques. The primary focus of this study lies in the development of an algorithm designed to optimize hip replacement procedures via the mechanical design of the prosthesis. This optimization process exploits the capabilities of machine learning algorithms, multi-body dynamics, and finite element method (FEM) simulations. The paramount innovation in this methodology is the capacity to design a prosthetic system that intricately adapts to the distinctive characteristics of each patient (weight, height, gait cycle). The primary objective of this research is to enhance the performance and longevity of prosthetic devices by improving their fatigue strength. The evaluation of load distribution on the prosthetic device, facilitated by FEM simulations, anticipates a substantial augmentation in the useful life of the prosthetic system. This research holds promise as a notable advancement in prosthetic technology, offering a more efficacious treatment option for patients suffering from joint arthritis. The aim of this research is to make meaningful contributions to the enhancement of patient quality of life and the long-term performance of prosthetic devices.

Background: Total hip arthroplasty (THA) is a widely adopted surgical intervention for restoring mobility and reducing pain in patients with severe hip joint conditions, such as osteoporosis. However, traditional titanium implants often lead to stress shielding and subsequent bone resorption due to the mismatch in stiffness between the implant and bone. Objectives: This study computationally investigates the biomechanical performance of femoral implants made from composite materials, specifically polyether-ether-ketone (PEEK) and polylactic acid (PLA) reinforced with hydroxyapatite (HA), compared to conventional titanium stems. Methods: Using finite element (FE) modeling, physiological loading during walking was simulated, and the strain energy density (SED) was analyzed to assess stress distribution and the potential for stress shielding across different Gruen zones. Results: The results indicate that both the PEEK and PLA composites exhibited more physiological load transfer, particularly in Gruen zones 1 and 7, reducing stress shielding and supporting bone preservation. Conclusions: These findings suggest that PEEK and PLA composites may offer improved implant stability and bone integration. Despite highlighting the promise of biomimetic materials in orthopedics, this study is limited to computational analysis and requires experimental validation. It emphasizes the need for further investigation using patient-specific geometries and a variety of loading scenarios to confirm these benefits and optimize femoral implant design.

The wear behaviour and chemical composition of orthodontic components influence the mechanical characteristics of a fixed orthodontic treatment. The purpose of this paper is to evaluate the surface alterations of different types of brackets (aesthetic, metallic, and conventional self-ligating) and archwires (superelastic and thermal) subjected to wear tests through optical microscopy and, subsequently, to identify the chemical elements of accessories by X-ray fluorescence. The cycles (5000 for each bracket and 10,000 for each wire) of the tribological test were carried out in dry conditions inside a machine that allows alternating sliding. The results of the study highlighted different wear behaviours even within the same type of brackets and archwires. The monocrystalline sapphire brackets maintain their aesthetic properties despite traces of wear inside the slots and contain minimal amounts of nickel. Superelastic NiTi archwires have a better overall rating than thermal wires, as they do not show significant surface wear alterations.

The knee is one of the joints most vulnerable to disease and injury, particularly in athletes and older adults. Surface temperature monitoring provides insights into the health of the analysed area, supporting early diagnosis and monitoring of conditions such as osteoarthritis and tendon injuries. This study presents an innovative approach that combines infrared thermography techniques with a Resnet 152 (DeepLabCut based) to detect and monitor temperature variations across specific knee regions during repeated sit-to-stand exercises. Thermal profiles are then analysed in relation to weight distribution data collected using a Wii Balance Board during the exercise. DeepLabCut was used to automate the selection of the region of interest (ROI) for temperature assessments, improving data accuracy compared to traditional time-consuming semi-automatic methods. This integrative approach enables precise and marker-free measurements, offering clinically relevant data that can aid in the diagnosis of knee pathologies, evaluation of the rehabilitation progress, and assessment of treatment effectiveness. The results emphasize the potential of combining thermography with DeepLabCut-driven data analysis to develop accessible, non-invasive tools for joint health monitoring or preventive diagnostics of pathologies.