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This study aimed to compare the cognitive performance and event-related potential (ERP) patterns between females who have given birth (parous) and those who have not (nulliparous). A total of 50 female participants, including 27 who were parous (33.2 ± 3.2 years) and 23 who were nulliparous (30.8 ± 2.3 years), were recruited. Only parous females who were ≤36 months postpartum (17.7 ± 8.1 months) were included. To compare the cognitive performance between the two groups, we presented the 3-back task (a working memory task) and compared the accuracy rate (%) and reaction time (ms) between the groups. Electroencephalogram (EEG) signals were simultaneously recorded and the ERP patterns at Fz, Cz, and Pz, which are highly associated with the 3-back task, were analyzed. From the ERP patterns, we extracted N100, P300, P600, P300 peak-to-peak (P300p_p), and P600 peak-to-peak (P600p_p). There were no significant between-group differences in terms of accuracy rate, reaction time, or ERP components (N100, P300, P600, P300p_p, or P600p_p) at the three sites (Fz, Cz, and Pz). Since this study, using meaningful objective data, did not show that parity was significantly correlated with cognitive performance ability and ERP patterns, childbirth does not appear to influence cognitive decline.
Mi-Hyun Choi; Jin-Ju Jung; Je-Hyeop Lee; Soon-Cheol Chung; Hyun-Kyung Park; Hyun-Jun Kim. Effect of Childbirth Experience on Cognitive Performance and Event-Related Potential Patterns. Applied Sciences 2021, 11, 3233 .
AMA StyleMi-Hyun Choi, Jin-Ju Jung, Je-Hyeop Lee, Soon-Cheol Chung, Hyun-Kyung Park, Hyun-Jun Kim. Effect of Childbirth Experience on Cognitive Performance and Event-Related Potential Patterns. Applied Sciences. 2021; 11 (7):3233.
Chicago/Turabian StyleMi-Hyun Choi; Jin-Ju Jung; Je-Hyeop Lee; Soon-Cheol Chung; Hyun-Kyung Park; Hyun-Jun Kim. 2021. "Effect of Childbirth Experience on Cognitive Performance and Event-Related Potential Patterns." Applied Sciences 11, no. 7: 3233.
This study was conducted to examine predictive factors of deep vein thrombosis (DVT) in gynecologic cancer survivors with lower extremity edema (LEE). In the current single-center, retrospective study, there was a total of 315 eligible patients, including 80 patients with DVT and 235 without DVT. They were therefore divided into two groups: the DVT group (n = 80) and the non-DVT group (n = 235). Then, baseline and clinical characteristics of the patients were compared between the two groups. In our study, distant organ metastasis, advanced stage, lymphadectomy, and amount of intraoperative blood loss had a positive predictive value for the occurrence of DVT in gynecologic cancer survivors presenting LEE. In conclusion, our results indicate that it is necessary to consider the possibility of LEE arising from DVT in gynecologic cancer survivors with advanced-stage cancer, distant organ metastasis, lymphadectomy, and intraoperative blood loss over 1500 mL.
Jungin Kim; Hyun-Jun Kim; Seunghun Park; Dong Kyu Kim; Tae Hee Kim. Predictive Factors of Deep Vein Thrombosis in Gynecologic Cancer Survivors with Lower Extremity Edema: A Single-Center and Retrospective Study. Healthcare 2020, 8, 48 .
AMA StyleJungin Kim, Hyun-Jun Kim, Seunghun Park, Dong Kyu Kim, Tae Hee Kim. Predictive Factors of Deep Vein Thrombosis in Gynecologic Cancer Survivors with Lower Extremity Edema: A Single-Center and Retrospective Study. Healthcare. 2020; 8 (1):48.
Chicago/Turabian StyleJungin Kim; Hyun-Jun Kim; Seunghun Park; Dong Kyu Kim; Tae Hee Kim. 2020. "Predictive Factors of Deep Vein Thrombosis in Gynecologic Cancer Survivors with Lower Extremity Edema: A Single-Center and Retrospective Study." Healthcare 8, no. 1: 48.
To compare the treatment effects of a high-dose and low-dose oral steroid regimen based on changes in the radioisotope uptake ratio (RUR) observed from three-phase bone scintigraphy (TPBS) in patients with complex regional pain syndrome type I (CRPS I), we retrospectively analyzed data of 34 patients with CRPS I from traumatic brain injury and stroke. Depending on the dose of steroid administered, patients were divided into high-dose (n = 14) and low-dose steroid groups (n = 20). We compared the severity scores, Kozin’s classification scores, and RUR observed from TPBS between the two groups. There were significant changes in the severity scores and Kozin’s classification between the baseline and 2 weeks from baseline (p < 0.05), however, there were no significant differences in terms of changes in the scores, classification, or the RUR observed from TPBS at 2 weeks from baseline (p > 0.05). There were no treatment-emergent adverse events (TEAEs) such as blood pressure elevation, impaired glycemic control, or gastrointestinal disturbances. Our results indicate that the efficacy profile of a low-dose oral steroid regimen is comparable to that of a high-dose regimen in alleviating symptoms in CRPS I patients. However, additional prospective, large-scale, multi-center studies are warranted to confirm our results.
Seunghun Park; Hyun-Jun Kim; Dong Kyu Kim; Tae Hee Kim. Use of Oral Prednisolone and a 3-Phase Bone Scintigraphy in Patients with Complex Regional Pain Syndrome Type I. Healthcare 2020, 8, 16 .
AMA StyleSeunghun Park, Hyun-Jun Kim, Dong Kyu Kim, Tae Hee Kim. Use of Oral Prednisolone and a 3-Phase Bone Scintigraphy in Patients with Complex Regional Pain Syndrome Type I. Healthcare. 2020; 8 (1):16.
Chicago/Turabian StyleSeunghun Park; Hyun-Jun Kim; Dong Kyu Kim; Tae Hee Kim. 2020. "Use of Oral Prednisolone and a 3-Phase Bone Scintigraphy in Patients with Complex Regional Pain Syndrome Type I." Healthcare 8, no. 1: 16.
Hyun-Jun Kim; Youjin Kim; Su Jin Lee; Jeeyun Lee; Se Hoon Park. Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study. Journal of Gynecologic Oncology 2018, 29, 1 .
AMA StyleHyun-Jun Kim, Youjin Kim, Su Jin Lee, Jeeyun Lee, Se Hoon Park. Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study. Journal of Gynecologic Oncology. 2018; 29 (1):1.
Chicago/Turabian StyleHyun-Jun Kim; Youjin Kim; Su Jin Lee; Jeeyun Lee; Se Hoon Park. 2018. "Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study." Journal of Gynecologic Oncology 29, no. 1: 1.
In the treatment of metastatic soft tissue sarcoma (STS), pazopanib is considered a standard treatment after failure of chemotherapy. We retrospectively investigated outcomes of pazopanib in patients with metastatic uterine STS.A retrospective study was performed on 35 consecutive patients with uterine STS treated with oral pazopanib 800 mg daily as salvage therapy for metastatic disease between September 2013 and December 2015. Endpoints included response rate, survival, and safety.Among 35 patients, 27 (77%) had a histologic diagnosis of leiomyosarcoma (LMS) and the median age was 57 years (range, 36-70). Median number of metastatic sites was one (range, 1-5) with lung as the most frequently involved site. Pazopanib was generally well-tolerated: the major hematologic toxicity was grade 1/2 anemia (14%). Among the non-hematologic toxicities, grade 1/2 stomatitis was most commonly observed (22%), followed by fatigue and hypertension. Objective response and stable disease were observed in 10 (29%) and 11 (31%) patients, respectively. However, most cases of clinical response were observed in patients with LMS: 33% for LMS, 20% for undifferentiated pleomorphic sarcoma, and 0% for endometrial stromal sarcoma. Median progression-free and overall survivals were 5.8 months (95% confidence interval [CI]=3.6-8.1) and 20.0 months (95% CI=11.6-28.4), respectively.In this "real-world" retrospective study, salvage therapy with pazopanib demonstrated clinically relevant efficacy and tolerability in unselected patients with uterine STS. Although it is encouraging that outcomes for Korean patients with uterine STS were similar to those reported in the phase III trial, the clinical benefit was limited to LMS.
Hyun-Jun Kim; Youjin Kim; Su Jin Lee; Jeeyun Lee; Se Hoon Park. Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study. Journal of Gynecologic Oncology 2018, 29, e3 -e3.
AMA StyleHyun-Jun Kim, Youjin Kim, Su Jin Lee, Jeeyun Lee, Se Hoon Park. Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study. Journal of Gynecologic Oncology. 2018; 29 (1):e3-e3.
Chicago/Turabian StyleHyun-Jun Kim; Youjin Kim; Su Jin Lee; Jeeyun Lee; Se Hoon Park. 2018. "Pazopanib monotherapy in the treatment of pretreated, metastatic uterine sarcoma: a single-center retrospective study." Journal of Gynecologic Oncology 29, no. 1: e3-e3.
The purpose of this study was to determine the levels of trace metals in the blood of the general Korean population. A total of 258 healthy individuals, according to their regular medical check-ups, (119 males and 139 females, age ranging from 12 to 78 years old) were enrolled from December 2014 to December 2016. Levels of 10 trace elements were determined using inductively coupled plasma mass spectrometry (ICP-MS). The geometric mean (GM) levels for lead, arsenic, cesium, mercury, aluminum, cadmium, copper, manganese, selenium, and zinc were 15.97 μg/L, 7.19 μg/L, 2.39 μg/L, 3.41 μg/L, 10.57 μg/L, 0.78 μg/L, 979.8 μg/L, 11.06 μg/L, 111.37 μg/L, and 872.7 μg/L, respectively. There were significant gender-related differences in the levels of several metals; male individuals had higher Pb, As, Cs, Hg, and Se than females, while females had higher Cd, Cu, and Mn than males. We noticed remarkably high blood levels of Hg, As and Al in the Korean population. The element concentrations reported represent a new contribution to the knowledge of the blood chemistry for the Korea population. The data can be used to assess the clinical health of this population.
Hyun-Jun Kim; Hwan-Sub Lim; Kyoung-Ryul Lee; Mi-Hyun Choi; Nam Mi Kang; Chang Hoon Lee; Eun-Jung Oh; Hyun-Kyung Park. Determination of Trace Metal Levels in the General Population of Korea. International Journal of Environmental Research and Public Health 2017, 14, 702 .
AMA StyleHyun-Jun Kim, Hwan-Sub Lim, Kyoung-Ryul Lee, Mi-Hyun Choi, Nam Mi Kang, Chang Hoon Lee, Eun-Jung Oh, Hyun-Kyung Park. Determination of Trace Metal Levels in the General Population of Korea. International Journal of Environmental Research and Public Health. 2017; 14 (7):702.
Chicago/Turabian StyleHyun-Jun Kim; Hwan-Sub Lim; Kyoung-Ryul Lee; Mi-Hyun Choi; Nam Mi Kang; Chang Hoon Lee; Eun-Jung Oh; Hyun-Kyung Park. 2017. "Determination of Trace Metal Levels in the General Population of Korea." International Journal of Environmental Research and Public Health 14, no. 7: 702.
Highlights•Alzheimer disease(AD), amnestic mild cognitive impairment(MCI),and healthy control(HC).•We investigated the difference in cognitive abilities and hippocampus volume (HV).•Hippocampus volume of AD and MCI subjects was relatively smaller than HC.•There were positive correlations between Boston naming test (BNT) and HV.•The BNT accurately differentiated the three groups by having the highest level of discrimination. AbstractThe study investigated differences in cognitive ability and hippocampal volume between groups of patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI), and healthy control (HC) subjects, and explored the relationship between cognitive ability and hippocampal volume. Among the sub-tests of Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-K), the Boston naming test score decreased in the order HC, aMCI, and AD. The hippocampal volumes of subjects with AD and aMCI were relatively smaller than those of HC individuals. There were strongly positive correlations between hippocampal volume and the scores for the Boston naming test. Discriminant analysis identified the Boston naming test as having the highest level of discrimination among the variables used to differentiate the three groups (89.9%). In conclusion, the Boston naming test accurately differentiated the three groups and was correlated with hippocampal volume. These results will be helpful for choosing an accurate and economically feasible test method that efficiently differentiates the three groups.
Mi-Hyun Choi; Hyung-Sik Kim; Seon-Young Gim; Woo-Ram Kim; Kyung-Ryul Mun; Gye-Rae Tack; Bongsoo Lee; Young Chil Choi; Hyun-Jun Kim; Seung Hwa Hong; Dae-Woon Lim; Soon-Cheol Chung. Differences in cognitive ability and hippocampal volume between Alzheimer’s disease, amnestic mild cognitive impairment, and healthy control groups, and their correlation. Neuroscience Letters 2016, 620, 115 -120.
AMA StyleMi-Hyun Choi, Hyung-Sik Kim, Seon-Young Gim, Woo-Ram Kim, Kyung-Ryul Mun, Gye-Rae Tack, Bongsoo Lee, Young Chil Choi, Hyun-Jun Kim, Seung Hwa Hong, Dae-Woon Lim, Soon-Cheol Chung. Differences in cognitive ability and hippocampal volume between Alzheimer’s disease, amnestic mild cognitive impairment, and healthy control groups, and their correlation. Neuroscience Letters. 2016; 620 ():115-120.
Chicago/Turabian StyleMi-Hyun Choi; Hyung-Sik Kim; Seon-Young Gim; Woo-Ram Kim; Kyung-Ryul Mun; Gye-Rae Tack; Bongsoo Lee; Young Chil Choi; Hyun-Jun Kim; Seung Hwa Hong; Dae-Woon Lim; Soon-Cheol Chung. 2016. "Differences in cognitive ability and hippocampal volume between Alzheimer’s disease, amnestic mild cognitive impairment, and healthy control groups, and their correlation." Neuroscience Letters 620, no. : 115-120.
Purpose: Despite conflicting data regarding survival after curative surgery, little is known about the prognosis of metastatic gastric cancer (MGC) in young adults. The current study was performed to determine whether younger age is an independent prognostic factor among MGC patients receiving first-line chemotherapy and to evaluate how age relates to other known prognostic parameters. Methods: The records of 1843 MGC patients who were consecutively treated with first-line combination chemotherapy at Samsung Medical Center (Seoul, Korea) between 2000 and 2007, including 570 patients aged 45 years or younger, were retrieved from a prospective cancer chemotherapy database.Results: In the younger group, there were significantly more bone metastases, ascites, poor performance status, low albumin, elevated alkaline phosphatase, and resections that were non-curative than in the older patients. Progression-free survival (PFS) and overall survival (OS) was shorter in younger patients (PFS, 4.2 months; OS, 7.1 months) than in older ones (PFS, 5.1 months; OS, 8.4 months). Nonetheless, younger age did not show an independent association with PFS or OS. Stratified analyses showed that younger age was related with poor outcome in the subgroups of good performance status and no bone metastasis. Conclusion: When matched for other prognostic factors, the prognosis of younger MGC patients receiving first-line combination chemotherapy does not differ from that of older patients. The poor survival of younger patients may be attributed to the association with other adverse prognostic factors.
Hyun-Jun Kim; Se Hoon Park. Outcomes of advanced gastric cancer in young adult patients treated with first-line combination chemotherapy. International Journal of Cancer Therapy and Oncology 2015, 3, 344 .
AMA StyleHyun-Jun Kim, Se Hoon Park. Outcomes of advanced gastric cancer in young adult patients treated with first-line combination chemotherapy. International Journal of Cancer Therapy and Oncology. 2015; 3 (4):344.
Chicago/Turabian StyleHyun-Jun Kim; Se Hoon Park. 2015. "Outcomes of advanced gastric cancer in young adult patients treated with first-line combination chemotherapy." International Journal of Cancer Therapy and Oncology 3, no. 4: 344.
The change of neuronal activation due to the passive perception of various driving speeds in comparison to a reference driving speed was assessed using functional Magnetic Resonance Imaging. Videos recorded in real driving conditions on the road at driving speeds of 50, 70, 90, and 110 km/h were shown as visual stimuli. An experiment consisted of three blocks, each having a control phase (50km/h) and a stimulation phase (70, 90, or 110 km/h). In the passive perception of various driving speed differences, the areas related to visual cognition and spatial attention such as temporal, occipital, parietal, frontal areas, and cerebellum were activated. As the driving speed difference increased, the number of activated voxels also increased in the areas related to visual cognition. However, the visual cognition related areas showed a different pattern from the spatial attention related area with an increase of the driving speed difference. This implies that each brain area has a different level of involvement in the passive perception of the driving speed difference, although both visual cognitions related areas and spatial attention related area are related to itclose
Hyun-Jun Kim; Jeong-Han Yi; Hyung-Sik Kim; Soon-Cheol Chung; Ji-Hye Baek; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Seon-Young Gim; Sung-Phil Kim; Dae-Woon Lim; Mi-Hyun Choi. Change of neuronal activations induced by the passive perception of driving speed difference. Bio-Medical Materials and Engineering 2015, 26, S833 -S840.
AMA StyleHyun-Jun Kim, Jeong-Han Yi, Hyung-Sik Kim, Soon-Cheol Chung, Ji-Hye Baek, Jung-Chul Lee, Sung-Jun Park, Ul-Ho Jeong, Seon-Young Gim, Sung-Phil Kim, Dae-Woon Lim, Mi-Hyun Choi. Change of neuronal activations induced by the passive perception of driving speed difference. Bio-Medical Materials and Engineering. 2015; 26 (s1):S833-S840.
Chicago/Turabian StyleHyun-Jun Kim; Jeong-Han Yi; Hyung-Sik Kim; Soon-Cheol Chung; Ji-Hye Baek; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Seon-Young Gim; Sung-Phil Kim; Dae-Woon Lim; Mi-Hyun Choi. 2015. "Change of neuronal activations induced by the passive perception of driving speed difference." Bio-Medical Materials and Engineering 26, no. s1: S833-S840.
The present study compared event-related potential (ERP) patterns for two stimuli types, puff and suction, by applying these stimuli to the fingers; ERP patterns for the two stimuli were compared at C3, an area related to somatosensory perception, and at FC5, an area related to motor function. Participants were 12 healthy males in their 20 s (mean age = 23.1 ± 2.0 years). One session consisted of a Control Phase (3 s), a Stimulation Phase (3 s), and a Rest Phase (9 s). During the Stimulation Phase, a 4-psi suction or puff stimulus was applied to the first joint of the right index finger. After completion of the session, a subjective magnitude test was presented. In all phases, electroencephalography signals were recorded. We extracted maximum positive amplitude and minimum negative amplitude as well as relevant latency values for C3 and FC5 signals. Suction and puff stimuli had similar subjective magnitude scores. For both C3 and FC5, the maximum and minimum amplitude latency was reached earlier for the suction stimulus than for the puff stimulus. In conclusion, when suction and puff stimuli of the same intensity were applied to the fingers, the suction stimulus caused a more sensitive response in the somatosensory area (C3) and motor area (FC5) than did the puff stimulus.close
Mi-Hyun Choi; Hyung-Sik Kim; Ji-Hye Baek; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Seon-Young Gim; Ji Hye You; Sung-Phil Kim; Dae-Woon Lim; Hyun-Jun Kim; Soon-Cheol Chung. Differing ERP patterns caused by suction and puff stimuli. Neuroscience Letters 2015, 594, 70 -75.
AMA StyleMi-Hyun Choi, Hyung-Sik Kim, Ji-Hye Baek, Jung-Chul Lee, Sung-Jun Park, Ul-Ho Jeong, Seon-Young Gim, Ji Hye You, Sung-Phil Kim, Dae-Woon Lim, Hyun-Jun Kim, Soon-Cheol Chung. Differing ERP patterns caused by suction and puff stimuli. Neuroscience Letters. 2015; 594 ():70-75.
Chicago/Turabian StyleMi-Hyun Choi; Hyung-Sik Kim; Ji-Hye Baek; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Seon-Young Gim; Ji Hye You; Sung-Phil Kim; Dae-Woon Lim; Hyun-Jun Kim; Soon-Cheol Chung. 2015. "Differing ERP patterns caused by suction and puff stimuli." Neuroscience Letters 594, no. : 70-75.
Mi-Hyun Choi; Hyung-Sik Kim; Jung-Chul Lee; Ji-Hye Baek; Sung-Jun Park; Ul-Ho Jeong; Hyun-Jun Kim; Soon-Cheol Chung; Byung-Chan Min. 2C1-3 Real-life accident factors for elderly patients with dementia. The Japanese Journal of Ergonomics 2015, 51, 1 .
AMA StyleMi-Hyun Choi, Hyung-Sik Kim, Jung-Chul Lee, Ji-Hye Baek, Sung-Jun Park, Ul-Ho Jeong, Hyun-Jun Kim, Soon-Cheol Chung, Byung-Chan Min. 2C1-3 Real-life accident factors for elderly patients with dementia. The Japanese Journal of Ergonomics. 2015; 51 (Supplement):1.
Chicago/Turabian StyleMi-Hyun Choi; Hyung-Sik Kim; Jung-Chul Lee; Ji-Hye Baek; Sung-Jun Park; Ul-Ho Jeong; Hyun-Jun Kim; Soon-Cheol Chung; Byung-Chan Min. 2015. "2C1-3 Real-life accident factors for elderly patients with dementia." The Japanese Journal of Ergonomics 51, no. Supplement: 1.
The present study addressed how 92% oxygen administration affects cognitive performance, blood oxygen saturation (SpO2), and heart rate (HR) of intellectually and developmentally disabled people. Seven males (28.9 ± 1.8 years) and seven females (34.4 ± 8.3 years) with intellectual and developmental disabilities (disabled level 2.1 ± 0.5) completed an experiment consisting a 0-back task with normal air (21% oxygen) administered in one run and hyperoxic air (92% oxygen) administered in the other run. The experimental sequence in each run consisted of a 1-min adaptation phase, 2-min control phase, and 2-min 0-back task phase, where SpO2 and HR were gauged for each phase. The administration of 92% oxygen increased 0-back task performance of intellectually and developmentally disabled people, in association with increased SpO2 and decreased HR. Our results demonstrate that sufficient oxygen supply subserving cognitive functions, even as a short-term effect, could increase cognitive ability for the intellectually and developmentally disabled people. It is concluded that enriched oxygen can positively affect, at least in the short-term, the working memory of those with intellectual and developmental disability.
Hyung-Sik Kim; Mi-Hyun Choi; Ji-Hye Baek; Sung-Jun Park; Jung-Chul Lee; Ul-Ho Jeong; Sung-Phil Kim; Hyun-Jun Kim; Young Chil Choi; Dae-Woon Lim; Soon-Cheol Chung. Effects of 92% oxygen administration on cognitive performance and physiological changes of intellectually and developmentally disabled people. Journal of Physiological Anthropology 2015, 34, 3 .
AMA StyleHyung-Sik Kim, Mi-Hyun Choi, Ji-Hye Baek, Sung-Jun Park, Jung-Chul Lee, Ul-Ho Jeong, Sung-Phil Kim, Hyun-Jun Kim, Young Chil Choi, Dae-Woon Lim, Soon-Cheol Chung. Effects of 92% oxygen administration on cognitive performance and physiological changes of intellectually and developmentally disabled people. Journal of Physiological Anthropology. 2015; 34 (1):3.
Chicago/Turabian StyleHyung-Sik Kim; Mi-Hyun Choi; Ji-Hye Baek; Sung-Jun Park; Jung-Chul Lee; Ul-Ho Jeong; Sung-Phil Kim; Hyun-Jun Kim; Young Chil Choi; Dae-Woon Lim; Soon-Cheol Chung. 2015. "Effects of 92% oxygen administration on cognitive performance and physiological changes of intellectually and developmentally disabled people." Journal of Physiological Anthropology 34, no. 1: 3.
The purpose of this study is to provide information for the protection of Korean homecare patients with senile dementia by investigating accident cases using a survey. With the survey of accident cases, the caregivers of 55 Korean homecare patients with senile dementia (75.9 ± 7.0 years) were administered the short form of the Samsung Dementia Questionnaire (S-SDQ) and an activities of daily living (ADL) test. Twelve risk elements were extracted. The order of frequency of occurrence from highest to lowest was "egress," "fall," "violence," "collision," "gas accident," "slip," "faucet misuse," "overeating," "drop," "discharge," "weird eating," and "self-injury." The percentage of risk elements resulting in physical harm was 40.1% across all risk elements. The risk elements resulting in the most physical harm were "fall," "collision," "slip," and "drop," respectively. Regarding the location of occurrence of risk elements, risk elements resulting in physical harm showed no significant differences between indoors and outdoors. Some risk elements, such as "egress," "fall," and "gas accident" happened concurrently with more than four other elements, while "collision," "drop," and "violence" happened together with more than two other elements. "Slip" happened significantly more often in the low ADL score group, while "gas accident" happened significantly more often in the high ADL score group. This study provides basic information about monitoring factors to protect senior homecare patients with senile dementia.
Mi-Hyun Choi; Hyung-Sik Kim; Boseong Kim; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Ji-Hye Baek; Hyun-Jun Kim; Dae-Woon Lim; Soon-Cheol Chung. Extraction and Analysis of Risk Elements for Korean Homecare Patients with Senile Dementia. The Journal of Behavioral Health Services & Research 2014, 43, 116 -126.
AMA StyleMi-Hyun Choi, Hyung-Sik Kim, Boseong Kim, Jung-Chul Lee, Sung-Jun Park, Ul-Ho Jeong, Ji-Hye Baek, Hyun-Jun Kim, Dae-Woon Lim, Soon-Cheol Chung. Extraction and Analysis of Risk Elements for Korean Homecare Patients with Senile Dementia. The Journal of Behavioral Health Services & Research. 2014; 43 (1):116-126.
Chicago/Turabian StyleMi-Hyun Choi; Hyung-Sik Kim; Boseong Kim; Jung-Chul Lee; Sung-Jun Park; Ul-Ho Jeong; Ji-Hye Baek; Hyun-Jun Kim; Dae-Woon Lim; Soon-Cheol Chung. 2014. "Extraction and Analysis of Risk Elements for Korean Homecare Patients with Senile Dementia." The Journal of Behavioral Health Services & Research 43, no. 1: 116-126.
This study investigated neuronal activation differences under two conditions: driving only and distracted driving. Driving and distraction tasks were performed using a Magnetic Resonance (MR)-compatible driving simulator with a driving wheel and pedal. The experiment consisted of three blocks, and each block had both a Rest phase (1 min) and a Driving phase (2 min). During the Rest phase, drivers were instructed to simply look at the stop screen without performing any driving tasks. During the Driving phase, each driver was required to drive at 110 km/h under two conditions: driving only and driving while performing additional distraction tasks. The results show that the precuneus, inferior parietal lobule, supramarginal gyrus, middle frontal gyrus, cuneus, and declive are less activated in distracted driving than in driving only. These regions are responsible for spatial perception, spatial attention, visual processing and motor control. However, the cingulate gyrus and sub-lobar regions (lentiform nucleus and caudate), which are responsible for error monitoring and control of unnecessary movement, show increased activation during distracted driving compared with driving only.
Soon-Cheol Chung; Mi-Hyun Choi; Hyung-Sik Kim; Na-Rae You; Sang-Pyo Hong; Jung-Chul Lee; Sung-Jun Park; Ji-Hye Baek; Ul-Ho Jeong; Ji-Hye You; Dae-Woon Lim; Hyun-Jun Kim. Effects of distraction task on driving: A functional magnetic resonance imaging study. Bio-Medical Materials and Engineering 2014, 24, 2971 -2977.
AMA StyleSoon-Cheol Chung, Mi-Hyun Choi, Hyung-Sik Kim, Na-Rae You, Sang-Pyo Hong, Jung-Chul Lee, Sung-Jun Park, Ji-Hye Baek, Ul-Ho Jeong, Ji-Hye You, Dae-Woon Lim, Hyun-Jun Kim. Effects of distraction task on driving: A functional magnetic resonance imaging study. Bio-Medical Materials and Engineering. 2014; 24 (6):2971-2977.
Chicago/Turabian StyleSoon-Cheol Chung; Mi-Hyun Choi; Hyung-Sik Kim; Na-Rae You; Sang-Pyo Hong; Jung-Chul Lee; Sung-Jun Park; Ji-Hye Baek; Ul-Ho Jeong; Ji-Hye You; Dae-Woon Lim; Hyun-Jun Kim. 2014. "Effects of distraction task on driving: A functional magnetic resonance imaging study." Bio-Medical Materials and Engineering 24, no. 6: 2971-2977.
This study investigated the correlation between young males' personal aggression and their skin conductance level (SCL) when watching aggression images. SCL increased when participants viewed aggression images as compared to control images. There was a negative correlation between personal aggression score and degree of change in SCL between aggression and control images.
Mi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Ji-Hye Kim; Jin-Seung Choi; Hyung-Sik Kim; Jang-Yeon Park; Jae-Hoon Jun; Gye-Rae Tack; Hyun-Jun Kim; Soon-Cheol Chung. An analysis of the correlation between young males' personal aggression and their skin conductance levels during exposure to aggression images. Psychiatry Research 2011, 186, 441 -442.
AMA StyleMi-Hyun Choi, Su-Jeong Lee, Jae-Woong Yang, Ji-Hye Kim, Jin-Seung Choi, Hyung-Sik Kim, Jang-Yeon Park, Jae-Hoon Jun, Gye-Rae Tack, Hyun-Jun Kim, Soon-Cheol Chung. An analysis of the correlation between young males' personal aggression and their skin conductance levels during exposure to aggression images. Psychiatry Research. 2011; 186 (2-3):441-442.
Chicago/Turabian StyleMi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Ji-Hye Kim; Jin-Seung Choi; Hyung-Sik Kim; Jang-Yeon Park; Jae-Hoon Jun; Gye-Rae Tack; Hyun-Jun Kim; Soon-Cheol Chung. 2011. "An analysis of the correlation between young males' personal aggression and their skin conductance levels during exposure to aggression images." Psychiatry Research 186, no. 2-3: 441-442.
The purpose of this study was to analyze the effects of smoking on corpus callosum volume. In addition, the relationships between smoking duration, smoking frequency, and corpus callosum volume were analyzed. Magnetic resonance brain images were acquired for 58 normal Korean men (30 smokers (age 32.82±14.12 years) and 28 non-smokers (age 35.49±13.11 years)). The corpus callosum volume was measured using Brain Voyager 2000S/W and was normalized by intracranical volume, which was calculated using cerebral sizes. The corpus callosum volume for smokers was significantly smaller than that for non-smokers. Also, there was a negative correlation between corpus callosum volume and smoking duration. The change of white matter volume (e.g., corpus callosum) might be a primary factor for characterizing the effects of smoking.
Mi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Ji-Hye Kim; Jin-Seung Choi; Jang-Yeon Park; Jae-Hoon Jun; Gye-Rae Tack; Beob-Yi Lee; Hyun-Jun Kim; Soon-Cheol Chung. Difference between smokers and non-smokers in the corpus callosum volume. Neuroscience Letters 2010, 485, 71 -73.
AMA StyleMi-Hyun Choi, Su-Jeong Lee, Jae-Woong Yang, Ji-Hye Kim, Jin-Seung Choi, Jang-Yeon Park, Jae-Hoon Jun, Gye-Rae Tack, Beob-Yi Lee, Hyun-Jun Kim, Soon-Cheol Chung. Difference between smokers and non-smokers in the corpus callosum volume. Neuroscience Letters. 2010; 485 (1):71-73.
Chicago/Turabian StyleMi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Ji-Hye Kim; Jin-Seung Choi; Jang-Yeon Park; Jae-Hoon Jun; Gye-Rae Tack; Beob-Yi Lee; Hyun-Jun Kim; Soon-Cheol Chung. 2010. "Difference between smokers and non-smokers in the corpus callosum volume." Neuroscience Letters 485, no. 1: 71-73.
The purpose of this study was to observe activation of the limbic system during the performance of visuospatial tasks under 21% O(2) or 30% O(2). Eight right-handed male college students were selected as subjects for this study. A visuospatial task was presented while brain images were scanned by a 3T fMRI system. The experiment consisted of the following two runs: a visuospatial task under normal air (21% O(2)) and a visuospatial task under hyperoxia (30% O(2)). The accuracy rate on the visuospatial task was enhanced during 30% O(2) compared to 21% O(2). The neural activation areas of the limbic system were similar in the cingulate gyrus, thalamus, limbic lobe and parahippocampal gyrus. Increased neural activation was observed in the cingulate gyrus and thalamus under 30% O(2) compared to 21% O(2). Under 30% O(2), the improvement in visuospatial task performance was related to an increase in neural activation of subcortical structures, such as the thalamus and cingulate gyrus, as well as the cerebral cortex.
Mi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Jin-Seung Choi; Hyung-Sik Kim; Hyun-Jun Kim; Byung-Chan Min; Se-Jin Park; Jae-Hoon Jun; Jeong-Han Yi; Gye-Rae Tack; Soon-Cheol Chung. Activation of the limbic system under 30% oxygen during a visuospatial task: An fMRI study. Neuroscience Letters 2010, 471, 70 -73.
AMA StyleMi-Hyun Choi, Su-Jeong Lee, Jae-Woong Yang, Jin-Seung Choi, Hyung-Sik Kim, Hyun-Jun Kim, Byung-Chan Min, Se-Jin Park, Jae-Hoon Jun, Jeong-Han Yi, Gye-Rae Tack, Soon-Cheol Chung. Activation of the limbic system under 30% oxygen during a visuospatial task: An fMRI study. Neuroscience Letters. 2010; 471 (2):70-73.
Chicago/Turabian StyleMi-Hyun Choi; Su-Jeong Lee; Jae-Woong Yang; Jin-Seung Choi; Hyung-Sik Kim; Hyun-Jun Kim; Byung-Chan Min; Se-Jin Park; Jae-Hoon Jun; Jeong-Han Yi; Gye-Rae Tack; Soon-Cheol Chung. 2010. "Activation of the limbic system under 30% oxygen during a visuospatial task: An fMRI study." Neuroscience Letters 471, no. 2: 70-73.
This study attempted to identify the effect of inhalation of highly concentrated oxygen on reaction time during simple visual matching tasks. Nine right-handed male graduate students (23.0 ± 1.4 years) participated in the study. Two subsets of simple visual matching tasks with similar difficulties were developed. The experiment consisted of visual matching tasks performed under two conditions: normal air (22.1% oxygen) and hyperoxic air (43.2% oxygen). There was a significant decrease in reaction time in the presence of 43.2% oxygen compared with the 22.1% oxygen condition. This result supports the hypothesis that hyperoxic air increase oxygen saturation level in the blood, lead to more available oxygen to the brain, thus increase the ability of cognitive processing.
Soon-Cheol Chung; Gye-Rae Tack; Mi-Hyun Choi; Soo-Jeong Lee; Jin-Seung Choi; Jeong-Han Yi; Bongsoo Lee; Jae-Hoon Jun; Hyun-Jun Kim; Se-Jin Park. Changes in reaction time when using oxygen inhalation during simple visual matching tasks. Neuroscience Letters 2009, 453, 175 -177.
AMA StyleSoon-Cheol Chung, Gye-Rae Tack, Mi-Hyun Choi, Soo-Jeong Lee, Jin-Seung Choi, Jeong-Han Yi, Bongsoo Lee, Jae-Hoon Jun, Hyun-Jun Kim, Se-Jin Park. Changes in reaction time when using oxygen inhalation during simple visual matching tasks. Neuroscience Letters. 2009; 453 (3):175-177.
Chicago/Turabian StyleSoon-Cheol Chung; Gye-Rae Tack; Mi-Hyun Choi; Soo-Jeong Lee; Jin-Seung Choi; Jeong-Han Yi; Bongsoo Lee; Jae-Hoon Jun; Hyun-Jun Kim; Se-Jin Park. 2009. "Changes in reaction time when using oxygen inhalation during simple visual matching tasks." Neuroscience Letters 453, no. 3: 175-177.
The purpose of the present study was to develop a magnetic resonance (MR) compatible photoplethysmograph (PPG) system that can measure the raw PPG signal during MR image acquisition. The system consists of an optic sensor that measures the optic signal, an optic cable that transmits a near-infrared optic signal, a signal amplifier, and a filter for noise removal. To minimize interactive noise, only the optic cable and the optic sensor module are located inside the MR room; the signal amplifier and filter are located outside the MR room. An experiment verified that a reliable PPG signal can be obtained without causing a deterioration in the MR image.
Soon-Cheol Chung; Ji-Hun Kwon; Bongsoo Lee; Jeong-Han Yi; Hyun-Jun Kim; Gye-Rae Tack. Development of a magnetic-resonance-compatible photoplethysmograph amplifier for behavioral and emotional studies. Behavior Research Methods 2008, 40, 342 -346.
AMA StyleSoon-Cheol Chung, Ji-Hun Kwon, Bongsoo Lee, Jeong-Han Yi, Hyun-Jun Kim, Gye-Rae Tack. Development of a magnetic-resonance-compatible photoplethysmograph amplifier for behavioral and emotional studies. Behavior Research Methods. 2008; 40 (1):342-346.
Chicago/Turabian StyleSoon-Cheol Chung; Ji-Hun Kwon; Bongsoo Lee; Jeong-Han Yi; Hyun-Jun Kim; Gye-Rae Tack. 2008. "Development of a magnetic-resonance-compatible photoplethysmograph amplifier for behavioral and emotional studies." Behavior Research Methods 40, no. 1: 342-346.
Rearrangements of the subtelomeric regions of chromosomes account for a significant proportion of the underlying genetic defects in both idiopathic mental retardation (MR) and multiple congenital anomalies. To detect the rearrangements, a set of subtelomeric fluorescence in situ hybridization (FISH) probes has been developed. The aim of this study was to reveal the frequency of subtelomeric rearrangements in Korean patients with MR or multiple anomalies. We performed a FISH study using a commercially available subtelomeric FISH probes on a series of unrelated Korean pediatric patients with MR or multiple anomalies without identifiable causes. We used a checklist to evaluate the developmental delay and/or MR. Patients who were shown to have chromosome abnormalities, metabolic disorders, or recognizable dysmorphic syndromes by clinical and laboratory findings were excluded. As a result, 100 patients were eligible for the Subtelomeric FISH study, and a total of 29 patients (29%) were suspected to have subtelomeric rearrangements on initial screening by the multiprobe FISH kit. Among theses, confirmatory FISH studies by using single locus-specific FISH probes were performed in 24 patients. One patient (a 10- yr-old girl) was confirmed to have rearrangement, deletion of the telomeric portion of the short arm of chromosome 4 (4p). Her clinical manifestation was compatible with Wolf-Hirschhorn syndrome, which is known to be caused by 4p deletion. The frequency of subtelomeric rearrangements in this study was 1.1% (1/95), lower than those previously reported (0.5-16.3%). We suggest that subtelomeric FISH test is a useful screening tool for patients with idiopathic MR and/or dysmorphism regardless of its false positive value.
Hyun-Kyung Park; Hee-Jin Kim; Hyun-Jun Kim; Sung-Hee Han; Young-Jae Kim; Sun-Hee Kim. Screening of Subtelomeric Rearrangements in 100 Korean Pediatric Patients with Unexplained Mental Retardation and Anomalies Using Subtelomeric FISH (Fluorescence In Situ Hybridization). Journal of Korean Medical Science 2008, 23, 573 -8.
AMA StyleHyun-Kyung Park, Hee-Jin Kim, Hyun-Jun Kim, Sung-Hee Han, Young-Jae Kim, Sun-Hee Kim. Screening of Subtelomeric Rearrangements in 100 Korean Pediatric Patients with Unexplained Mental Retardation and Anomalies Using Subtelomeric FISH (Fluorescence In Situ Hybridization). Journal of Korean Medical Science. 2008; 23 (4):573-8.
Chicago/Turabian StyleHyun-Kyung Park; Hee-Jin Kim; Hyun-Jun Kim; Sung-Hee Han; Young-Jae Kim; Sun-Hee Kim. 2008. "Screening of Subtelomeric Rearrangements in 100 Korean Pediatric Patients with Unexplained Mental Retardation and Anomalies Using Subtelomeric FISH (Fluorescence In Situ Hybridization)." Journal of Korean Medical Science 23, no. 4: 573-8.