Mirza Dedić

Prof. Mirza Dedić

Assistant Professor Faculty of Pharmacy University of Sarajevo
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 March 2022 in Molecules
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Journal Article
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Belma ImamovićBelma Imamović
Belma Imamović
Polonca TrebsePolonca Trebse
Polonca Trebse
EOElma Omeragic
Elma Omeragic
Ervina BečićErvina Bečić
Ervina Bečić
APAndrej Pečet
Andrej Pečet
Mirza DedićMirza Dedić
Mirza Dedić
Benzophenone (BP) type UV filters are common environmental contaminants that are posing a growing health concern due to their increasing presence in water. Different studies have evidenced the presence of benzophenones (BP, BP-1, BP-2, BP-3, BP-4, BP-9, HPB) in several environmental matrices, indicating that conventional technologies of water treatment are not able to remove them. It has also been reported that these compounds could be associated with endocrine-disrupting activities, genotoxicity, and reproductive toxicity. This review focuses on the degradation kinetics and mechanisms of benzophenone-type UV filters and their degradation products (DPs) under UV and solar irradiation and in UV-based advanced oxidation processes (AOPs) such as UV/H2O2, UV/persulfate, and the Fenton process. The effects of various operating parameters, such as UV irradiation including initial concentrations of H2O2, persulfate, and Fe2+, on the degradation of tested benzophenones from aqueous matrices, and conditions that allow higher degradation rates to be achieved are presented. Application of nanoparticles such as TiO2, PbO/TiO2, and Sb2O3/TiO2 for the photocatalytic degradation of benzophenone-type UV filters was included in this review.

3 February 2021 in Applied Sciences
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Journal Article
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Belma ImamovićBelma Imamović
Belma Imamović
Irmela IvazovićIrmela Ivazović
Irmela Ivazović
Amra AlispahicAmra Alispahic
Amra Alispahic
Ervina BečićErvina Bečić
Ervina Bečić
Mirza DedićMirza Dedić
Mirza Dedić
Armina DacićArmina Dacić
Armina Dacić
Anti-aging cosmetics are often sought after in order to slow down the aging process. Free radicals are one of the main causes of skin aging, and therefore antioxidants are used in anti-aging cosmetics. The aim of this study was to investigate which method is the most suitable for determining the antioxidant capacity of these products. Having samples extracted, the antioxidant capacity of the extracts obtained was determined by the following spectrophotometric methods: DPPH, Folin-Ciocalteu, FRAP, the ABTS method and the ferroion chelation method with ferrosine. The antioxidant capacity of the samples varied depending on the extract type and the method used. DPPH and ferroion chelation measurements with ferrosine were carried out in the part of the spectrum where plant pigments absorb. These pigments are often found in anti-aging products affecting these methods measurement results. The Folin-Ciocalteu method is suitable for researching the antioxidant capacity of hydrophilic extracts, but not lipophilic ones, where turbidity and the formation of a gelled ring occur. The FRAP method revealed similar results for all the samples and proved to be less sensitive than the others. The ABTS method for both types of extracts has proven to be the most suitable and sensitive method for determining the antioxidant capacity of anti-aging products.

27 November 2020 in Pharmacia
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Mirza DedićMirza Dedić
Mirza Dedić
SGSanjin Gutic
Sanjin Gutic
AGArmina Gicevic
Armina Gicevic
EBErvina Becic
Ervina Becic
Belma ImamovićBelma Imamović
Belma Imamović
NZNermina Ziga-Smajic
Nermina Ziga-Smajic
This paper shows the use of membrane filters in adsorption of solution of tetracycline hydrochloride on graphene materials. The adsorption process was monitored at different wavelengths, different pH values ​​at certain time intervals. The absorbances of the solutions were measured by UV-Vis spectrophotometry at two wavelengths (275 nm and 356 nm), and three pH values (pH 4, pH 7 and pH 10) every 90 minutes for 6 hours of monitoring, with constant stirring in an ultrasonic bath. The results showed decrease in absorbance at both wavelength and in all three pH values which proved the adsorption of tetracycline hydrochloride on GO and rGO. The largest decrease in absorbance was 98.1%. The most suitable pH value for adsorption was pH 4. This paper used a unique approach to filtration through membrane filters, which in the future could lead to the development of membrane filters based on graphene materials.

7 January 2021 in Pharmacia
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Journal Article
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EOElma Omeragic
Elma Omeragic
AMAleksandra Marjanovic
Aleksandra Marjanovic
JDJasmina Djedjibegovic
Jasmina Djedjibegovic
ATAmila Turalic
Amila Turalic
Mirza DedićMirza Dedić
Mirza Dedić
MSMiroslav Sober
Miroslav Sober
Objectives: Food supplements and medicines which are not on the list of prohibited substances of the World Anti-Doping Agency are included in the group of permitted pharmacological agents for athlete’s recovery. The aim of this study was to describe qualitatively and quantitatively food supplements (FS) and over-the-counter drugs use among athletes in the last six month. Methods: This was a cross sectional study. Data on food supplements and the over-the-counter drugs, usage were collected during 2018 by self-administered, anonymous questionnaire. Results: A total of 112 athletes completed the survey. A total of 51.8% (n = 58) athletes reported the use of food supplements. The use of medical supplements was reported by 50.0% (n = 56) of athletes, 26.8% (n = 30) reported using ergogenic supplements, 1.8% (n = 2) using of sports food and 4.5% (n = 5) using other supplements. The use of over-the-counter drugs was reported by 35.7% (n = 40) of athletes. The over-the-counter analgesic drugs were used by 95% (n = 38) of over-the-counter drug users. Concomitant administration two or more over-the-counter drugs was reported by 40% (n = 16) athletes. Doctors and coaches had no advisory role in the use of food supplements or over-the-counter drugs.

15 March 2017
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Book Chapter
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VTVedad Terzić
Vedad Terzić
ATArnela Tarakčija
Arnela Tarakčija
AVAlmir Vardo
Almir Vardo
AHAlma Hadžajlić
Alma Hadžajlić
VŠVildana Šakić
Vildana Šakić
Mirza DedićMirza Dedić
Mirza Dedić

30 November 2023 in Boletin Latinoamericano Y Del Caribe de Plantas Medicinales Y Aromaticas
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Journal Article
Closed access
USUniversity of Sarajevo
University of Sarajevo
NJNadir Jordamovc
Nadir Jordamovc
Belma Pehlivanović KelleBelma Pehlivanović Kelle
Belma Pehlivanović Kelle
HNHaris Nikšić
Haris Nikšić
IGIrma Gusic
Irma Gusic
KDKemal Duric
Kemal Duric
Triterpenes are very important secondary metabolites with wide structural diversity and significant role in pharmacy and medicine.In the present research, a comparative study of pharamacological activities of the triterpene fractions obtained from several plant species belonging to Lamiaceae family, was carried out. In-vitro anti-proliferative activity was performed using a standardproliferation assay based on tetrazolium salts. In vitro anti-inflammatory activity of triterpene fractions was determined by an assay of inhibition of albumin denaturation. In general, the triterpene fractions obtained from plant species belonging to Lamiaceae family showed a strong anti-proliferative activity and anti-inflammatory activity.The triterpene fraction of Rosmarini folium showed the strongest anti-proliferative activity (GI50range from 4 to 37 μg/ml) and the strongest anti-inflammatory activity in the range from 57.27% to 80.69%. This comparative study provides scientific evidence to support the traditional use of Lamiacae plant species for medical purposes as anti-inflammatory and anti-proliferative medicines.