Intravenous delivery is the fastest conventional method of delivering drugs to their targets in seconds, whereas intramuscular and subcutaneous injections provide a slower continuous delivery of drugs. In recent years, nanoparticle-based drug-delivery systems have gained considerable attention. During the progression of nanoparticles into the blood, the sound waves generated by the particles create acoustic pressure that affects the movement of nanoparticles. To overcome this issue, the impact of sound pressure levels on the development of nanoparticles was studied herein. In addition, a composite nanostructure was developed using different types of nanoscale substances to overcome the effect of sound pressure levels in the drug-delivery process. The results demonstrate the efficacy of the proposed nanostructure based on a group of different nanoparticles. This study suggests five materials, namely, polyimide, acrylic plastic, Aluminum 3003-H18, Magnesium AZ31B, and polysilicon for the design of the proposed structure. The best results were obtained in the case of the movement of these molecules at lower frequencies. The performance of acrylic plastic is better than other materials; the sound pressure levels reached minimum values at frequencies of 1, 10, 20, and 60 nHz. Furthermore, an experimental setup was designed to validate the proposed idea using advanced biomedical imaging technologies. The experimental results demonstrate the possibilities of detecting, tracking, and evaluating the movement behaviors of nanoparticles. The experimental results also demonstrate that the lowest sound pressure levels were observed at lower frequency levels, thus proving the validity of the proposed computational model assumptions. The outcome of this study will pave the way to understand the interaction behaviors of nanoparticles with the surrounding biological environments, including the sound pressure effect, which could lead to the useof such an effect in facilitating directional and tactic movements of the micro- and nano-motors.

In this paper, we propose an indoor visible light communication (VLC) system which makes use of Walsh precoding and multiple light-emitting diodes (LEDs) at the transmitter for multiplexing the data. The proposed VLC system is based on intensity modulation and uses the notion of spatial modulation for communicating the positive and negative values of the synthesized transmit signal using signal processing technique at the transmitter. We also illustrate the flexibility, ability, and easiness of the system to configure well in a multiuser environment. We have also developed a near-maximum likelihood (ML) detection technique for efficiently decoding the data bits at the receiver. The proposed near-ML reduces the search space involved in ML technique by using the initial ZF solution. The results of the simulation studies illustrate that the proposed technique offers a higher data rate and good bit error rate (BER) performance in indoor VLC environments.

Measuring Void Fraction (VF) in a pipeline is crucial for ensuring operational efficiency, safety, and environmental responsibility in various engineering applications. There are several methods commonly used to measure VF in multiphase flow systems. Capacitance sensors are a dependable and...