In recent decades, studies on the functional features of Se nanoparticles (SeNP) have gained great popularity due to their high biocompatibility, stability, and pronounced selectivity. A large number of works prove the anticarcinogenic effect of SeNP. In this work, the molecular mechanisms regulating the cytotoxic effects of SeNP, obtained by laser ablation, were studied by the example of four human cancer cell lines: A-172 (glioblastoma), Caco-2, (colorectal adenocarcinoma), DU-145 (prostate carcinoma), MCF-7 (breast adenocarcinoma). It was found that SeNP had different concentration-dependent effects on cancer cells of the four studied human lines. SeNP at concentrations of less than 1 μg/mL had no cytotoxic effect on the studied cancer cells, with the exception of the A-172 cell line, for which 0.5 μg/mL SeNP was the minimum concentration affecting its metabolic activity. It was shown that SeNP concentration-dependently caused cancer cell apoptosis, but not necrosis. In addition, it was found that SeNP enhanced the expression of pro-apoptotic genes in almost all cancer cell lines, with the exception of Caco-2 and activated various pathways of adaptive and pro-apoptotic signaling pathways of UPR. Different effects of SeNP on the expression of ER-resident selenoproteins and selenium-containing glutathione peroxidases and thioredoxin reductases, depending on the cell line, were established. In addition, SeNP triggered Ca²⁺ signals in all investigated cancer cell lines. Different sensitivity of cancer cell lines to SeNP can determine the induction of the process of apoptosis in them through regulation of the Ca²⁺ signaling system, mechanisms of ER stress, and activation of various expression patterns of genes encoding pro-apoptotic proteins.

Long-lived luminescence in the blue region was found to occur in deionized water saturated with atmospheric gases following mechanical shaking. Luminescence intensity decreased exponentially after the cessation of stress. During vigorous mechanical shaking, we observed gas bubbles in solution, and the liquid–gas interface area increased noticeably. At the same time, the concentration of molecular oxygen decreased, which could not be attributed to the water warming up with exposure to mechanical stress. However, deaerated water rapidly became saturated with gases following mechanical stress. The recommendation that cell culture media should be mixed after they are removed from the fridge in order to allow saturation with oxygen is probably misleading. It was shown that gases existed in water both in the form of individual molecules and nanobubbles. Mechanical stress did not influence the number or size of nanobubbles. While gas nanobubbles were absent in freshly prepared deaerated water, they appeared following exposure to mechanical stress. In addition, in mechanically treated gas-saturated water, there was seemingly an equilibrium shift towards the decomposition of carbonic acid to water and carbon dioxide. At the same time, the pH of water tended to increase immediately after mechanical stress. It was demonstrated that reactive oxygen species (ROS) form in gas-saturated water under mechanical stress (30 Hz, amplitude of 5 mm). The relative generation rate of hydrogen peroxide and of the hydroxyl radical was 1 nM/min and 0.5 nM/min, respectively. It was found that with an increase in the frequency of mechanical action (f), the rate of ROS generation increased in proportion to f ². The major pathways for hydrogen peroxide generation are probably associated with the formation of singlet oxygen and its further reduction, and the alternative pathway is the formation of hydrogen peroxide as a result of hydroxyl radical recombination.

In this study, we investigated the effects of additional ultraviolet radiation (UV) on the main growth fluorescent lamp light on pigment content and essential oil accumulation in sweet basil (Ocimum basilicum L.). Three different UV light sources from light-emitting diodes and discharge lamps, which emit UV in the UV-A (315–400 nm), UV-B (280–315 nm) and UV-C (100–280 nm) ranges, were tested for basil plant growing. The plants, growing under additional UV-A and UV-B from mercury lamps, on the 60th growing day were higher than control plants by 90% and 53%, respectively. The fresh leaf mass of the UV-A irradiated basil plants was 2.4-fold higher than the control plant mass. The dry mass/fresh mass ratio of the UV-A and UV-B irradiated plants was higher by 45% and 35% in comparison to the control plants. Leaf area was increased by 40% and 20%, respectively. UV-C affected the anthocyanin content most strongly, they increased by 50%, whereas only by 27% and 0% under UV-A and UV-B. Any UV addition did not affect the essential oil total contents but altered the essential oil compositions. UV-A and UV-B increased the linalool proportion from 10% to 20%, and to 25%, respectively, in contrast to UV-C, which reduced it to 3%. UV-C induced the eugenol methyl ether accumulation (17%) and inhibited plant growth. Moreover, UV increased the proportion of α-guaiene, β-cubebene and α-bulnesene and decreased the proportion of sabinene and fenchone. Thus, we concluded that UV (except UV-C) used jointly with main light with PPFD 120 ± 10 μmol photons·m⁻²·s⁻¹ for sweet basil cultivation may be justified to stimulate basil growth and optimize the essential oil accumulation.

The influence of compensation of the geomagnetic field to levels below 0.4 μT (referred to below as “zero magnetic field”) on human cognitive processes has been studied. 40 participants in the study were assigned to four groups according to their gender and age. The study focused on the assessment of cognitive processes. Each participant took part in two experiments, one of which was set up under normal (control) conditions, whereas the second one was set up under the conditions of a zero magnetic field. 45 min of exposure to zero magnetic field caused statistically significant changes in five out of eight parameters in the cognitive tests. The magnitude of the effects varied between 1.3 and 6.2%, with an average value of 2.1% for all tests ( p < 0.002, MANOVA). It was found that exposure to a zero magnetic field resulted in an increased number of errors and extension of the time required to complete the tasks compared to normal conditions. Men outperformed women under zero magnetic field conditions and young people performed better than older people. It was found that factors other than age and gender affected the cognitive performance under zero magnetic field conditions.

The effect of a static magnetic field with induction up to 7 T on the concentration of dissolved molecular oxygen, the concentration of hydrogen peroxide, the redox potential, and the electrical conductivity of aqueous solutions with a low concentration of active impurities is studied. It was shown that the concentration of dissolved molecular oxygen in water under the exposure of a magnetic field with induction up to 7 T does not change significantly, while the concentration of hydrogen peroxide increases linearly. It has been established that the pH value of water with field amplification in this induction range tends to decrease within 10%. With an increase in induction, an increase in the redox potential of water is observed. The change in its value is approximately 7 mV/T. It was shown that, with an increase in induction up to 2 T, the electrical resistivity of the water under study drops to about 0.6 MΩ cm, while at higher values of induction it practically does not change.