Bartosz Skalski

Dr. Bartosz Skalski

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
15 March 2018 in Frontiers in Pharmacology
Verified
Journal Article
Open access
PDF file
BOBeata Olas
Beata Olas
BSBartosz Skalski
Bartosz Skalski
KUKarolina Ulanowska
Karolina Ulanowska
Various parts of sea buckthorn [Elaeagnus rhamnoides (L.) A. Nelson], particularly the berries, known also as seaberries, or Siberian pineapples, are characterized by a unique composition of bioactive compounds: phenolic compounds, vitamins (especially vitamin C), unsaturated fatty acids, and phytosterols such as beta-sitosterol. These berries, together with the juices, jams, and oils made from them, have a range of beneficial antioxidant, anti-inflammatory, and anticancer effects. This short review discusses whether sea buckthorn may represent a “golden mean” for the treatment of cancers: It has anti-proliferation properties and can induce apoptosis and stimulate the immune system, and sea buckthorn oil counteracts many side effects of chemotherapy by restoring kidney and liver function, increasing appetite, and keeping patients in general good health. Although the anticancer activity of sea buckthorn has been confirmed by many in vitro and animal in vivo studies, the treatment and prophylactic doses for humans are unknown. Therefore, greater attention should be paid to the development of well-controlled and high-quality clinical experiments in this area.

1 March 2019 in Food and Chemical Toxicology
Verified
Journal Article
Closed access
BSBartosz Skalski
Bartosz Skalski
BLBernadetta Lis
Bernadetta Lis
Łukasz PecioŁukasz Pecio
Łukasz Pecio
BKBogdan Kontek
Bogdan Kontek
BOBeata Olas
Beata Olas
ASAnna Stochmal
Anna Stochmal


31 October 2024 in Molecules
Verified
Journal Article
Open access
PDF file
AKAndrzej Krzykowski
Andrzej Krzykowski
SRStanisław Rudy
Stanisław Rudy
Renata PolakRenata Polak
Renata Polak
Beata BiernackaBeata Biernacka
Beata Biernacka
AKAnna Krajewska
Anna Krajewska
DDDariusz Dziki
Dariusz Dziki
Studies were conducted focusing on the drying of chili pepper fruits (Capsicum annuum L.), cultivar Cyklon, using convective (AD), convective-microwave (AMD), vacuum (VD), and freeze-drying (FD) methods. The influence of the drying method and temperature on the kinetics of the process and selected quality attributes of the dried product were evaluated. It was demonstrated that the Midilli model best described the drying kinetics for all methods across the entire measurement range. FD and VD produced dried products with the highest brightness and the greatest value of the a* color parameter. The lowest b* color parameter was observed for the product dried using FD at 40 °C, while the highest b* value was noted for samples dried using AMD (100 W) at 60 °C. The highest carotenoid retention was achieved with the FD method at 40 °C, while the lowest carotenoid content was found in the product obtained using the AMD method (100 W) at 60 °C. The smallest losses of capsaicinoids were observed after FD drying at 40 °C, while the largest were found for AMD (100 W) at 60 °C. The analysis of chili pepper fruit extracts revealed the quantitative composition of 12 main phenolic compounds using the UHPLC-UV method. The highest polyphenol content was obtained with FD, while the lowest total polyphenol content was recorded after AD. Regardless of temperature, the total flavonoid content was highest in extracts from FD products, and the lowest flavonoid content was found after AMD at 100 W. For all drying methods analyzed, the total flavonoid content in the pepper extracts decreased with increasing temperature.

1 December 2020 in Agronomy
Verified
Journal Article
Open access
PDF file
MKMałgorzata Kubczak
Małgorzata Kubczak
AKAinur B. Khassenova
Ainur B. Khassenova
BSBartosz Skalski
Bartosz Skalski
Sylwia MichlewskaSylwia Michlewska
Sylwia Michlewska
MWMarzena Wielanek
Marzena Wielanek
Maksim IonovMaksim Ionov
Maksim Ionov
It is important to search for new sources of bioactive, natural compounds, because customers are paying more attention to food quality. Fruits and berries from horticultural plants are known to be good sources of agents beneficial for human well-being and could serve as natural preservatives in the food industry. However, more recent research indicates that other plant organs can also be rich in nutrients. Our study focused on characterizing an unexplored source, namely leaf and twig extracts from Rosa canina. The chemical composition of these extracts was analyzed and their in vitro activity measured. HPLC analysis of the content of phenolics, vitamins and amino acids revealed that the leaf and twig extracts were found to be rich in bioactive compounds with potent antioxidant properties. The greatest differences between bioactive phenolic compounds in leaf and twig extracts related mainly to p-coumaric acid, myricetin, ellagic acid, cyanidin, procyanidin and quercetin, whereas salicylic acid levels were similar in both types of extract. Interactions with human serum albumin were investigated, and some conformational changes in protein structure were observed. Further analysis (lipid peroxidation, protein carbonylation, thiol group oxidation, DPPH inhibition and ROS inhibition) confirmed that both leaf and twig extracts exhibited antioxidant and antiradical scavenging activities. Cytotoxicity and hemotoxicity assays confirmed very low toxicity of the extracts towards human cells over the range of concentrations tested. Our results indicate that both extracts could serve as non-toxic sources of bioactive compounds with antiradical properties.

25 January 2025 in Nutrients
Verified
Journal Article
Open access
PDF file
BSBartosz Skalski
Bartosz Skalski
EKElzbieta Kuzniak
Elzbieta Kuzniak
Iwona KowalskaIwona Kowalska
Iwona Kowalska
MSMonika Sikora
Monika Sikora
BOBeata Olas
Beata Olas
Schisandra chinensis is a plant from the Schisandraceae family that grows in humid climates, such as forests and mountain slopes. This plant is attracting the attention of an increasing number of scientists around the world, mainly due to its medicinal properties. It contains a variety of bioactive compounds that exhibit significant biological activities, including lignans, flavonoids, phenolic acids, triterpenoids, organic acids and essential oils. This publication is a review of the latest knowledge and research conducted in the field of analysis of biologically active compounds isolated from Schisandra chinensis.