Najeeb Ullah

Dr. Najeeb Ullah

Xi’an Jiao Tong University
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 November 2024 in Plants
Verified
Journal Article
Open access
PDF file
Rasheed AkbarRasheed Akbar
Rasheed Akbar
Jianfan sunJianfan sun
Jianfan sun
YBYanwen Bo
Yanwen Bo
Wajid Ali KhattakWajid Ali Khattak
Wajid Ali Khattak
AKAmir Abdullah Khan
Amir Abdullah Khan
Daolin DuDaolin Du
Daolin Du
The invasion of non-native plant species presents a significant ecological challenge worldwide, impacting native ecosystems and biodiversity. These invasive plant species significantly affect the native ecosystem. The threat of invasive plant species having harmful effects on the natural ecosystem is a serious concern. Invasive plant species produce secondary metabolites, which not only help in growth and development but are also essential for the spread of these plant species. This review highlights the important functions of secondary metabolites in plant invasion, particularly their effect on allelopathy, defense system, interaction with micro soil biota, and competitive advantages. Secondary metabolites produced by invasive plant species play an important role by affecting allelopathic interactions and herbivory. They sometimes change the soil chemistry to make a viable condition for their proliferation. The secondary metabolites of invasive plant species inhibit the growth of native plant species by changing the resources available to them. Therefore, it is necessary to understand this complicated interaction between secondary metabolites and plant invasion. This review mainly summarizes all the known secondary metabolites of non-native plant species, emphasizing their significance for integrated weed management and research.

1 October 2021 in CNS & Neurological Disorders - Drug Targets
Verified
Journal Article
Closed access
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Md Belal Bin HeyatMd Belal Bin Heyat
Md Belal Bin Heyat
FAFaijan Akhtar
Faijan Akhtar
MKMasood Hasan Khan
Masood Hasan Khan
NUNajeeb Ullah
Najeeb Ullah
IGIjaz Gul
Ijaz Gul
DLDakun Lai
Dakun Lai
Background: Lack of sleep generates many disorders and bruxism is one of them. It has affected almost 31% of the world population. Aim: The purpose of this paper is to determine the volume of the research conducted on bruxism and to create a database. We aimed to highlight critical issues for further research commitments and communications. This paper designs a comprehensive and very perception-based picture of bruxism disorder. Methods: The research-based work uses three methods, including a systematic mapping process, network visualization, and literature review. Softwares, such as VOSviewer, MATLAB, and MEGA- X, have been utilized to analyze the work. We have researched deep insights of information to retrieve the present understanding of bruxism disorder from dental to psychological concepts, from engineering detection to clinical treatment, and from temporomandibular disorder to biological genes. Results: We found 10 keywords and 77 items of bruxism in PubMed, Scopus, Google Scholar, and Web of Science databases based on previous publications. These keywords and items are helpful for all types of researchers, which include engineering, science, and medical background personals. 11 genes and 75 research articles with approximately 115,077 subjects, for the analysis of detection, treatment, child and adolescent bruxism, have been reviewed in the research work. Conclusion: It has been found that bruxism altogether has sleep, neurological, dental, and genetic disorder components and is a complex phenomenon. This study has also mentioned the future direction and gap in research conducted so far on bruxism and has also tried to provide goals for the upcoming research to be accomplished in a more significant and scientific manner.

1 April 2022 in Talanta
Verified
Journal Article
Closed access
BNBeenish Noureen
Beenish Noureen
NUNajeeb Ullah
Najeeb Ullah
YTYulan Tian
Yulan Tian
Liping DuLiping Du
Liping Du
Wei ChenWei Chen
Wei Chen
Ping WangPing Wang
Ping Wang

20 July 2021 in Sensors
Verified
Journal Article
Open access
PDF file
NUNajeeb Ullah
Najeeb Ullah
Wei ChenWei Chen
Wei Chen
BNBeenish Noureen
Beenish Noureen
YTYulan Tian
Yulan Tian
Liping DuLiping Du
Liping Du
JMJie Ma
Jie Ma
Saxitoxin (STX) belongs to the family of marine biological toxins, which are major contaminants in seafood. The reference methods for STX detection are mouse bioassay and chromatographic analysis, which are time-consuming, high costs, and requirement of sophisticated operation. Therefore, the development of alternative methods for STX analysis is urgent. Electrochemical analysis is a fast, low-cost, and sensitive method for biomolecules analysis. Thus, in this study, an electrolyte-insulator-semiconductor (EIS) sensor based on aptamer-modified two-dimensional layered Ti3C2Tx nanosheets was developed for STX detection. The high surface area and rich functional groups of MXene benefited the modification of aptamer, which had specific interactions with STX. Capacitance-voltage (C-V) and constant-capacitance (ConCap) measurement results indicated that the aptasensor was able to detect STX with high sensitivity and good specificity. The detection range was 1.0 nM to 200 nM and detection limit was as low as 0.03 nM. Moreover, the aptasensor was found to have a good selectivity and two-week stability. The mussel tissue extraction test suggested the potential application of this biosensor in detecting STX in real samples. This method provides a convenient approach for low-cost, rapid, and label-free detection of marine biological toxins.

14 October 2024 in Biosensors
Verified
Journal Article
Open access
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WHWajid Hussain
Wajid Hussain
HWHuan Wang
Huan Wang
XYXiaohan Yang
Xiaohan Yang
Muhammad Wajid UllahMuhammad Wajid Ullah
Muhammad Wajid Ullah
JHJawad Hussain
Jawad Hussain
SWShenqi Wang
Shenqi Wang
The rapid and sensitive detection of Salmonella typhimurium in food matrices is crucial for ensuring food safety. This study presents the development of an ultrasensitive electrochemical biosensor using surface-modified bacterial cellulose (BC) integrated with polypyrrole (Ppy) and reduced graphene oxide (RGO), further functionalized with immobilized S. typhimurium-specific phage particles. The BC substrate, with its ultra-fibrous and porous structure, was modified through in situ oxidative polymerization of Ppy and RGO, resulting in a highly conductive and flexible biointerface. The immobilization of phages onto this composite was facilitated by electrostatic interactions between the polycationic Ppy and the negatively charged phage capsid heads, optimizing phage orientation and enhancing bacterial capture efficiency. Morphological and chemical characterization confirmed the successful fabrication and phage immobilization. The biosensor demonstrated a detection limit of 1 CFU/mL for S. typhimurium in phosphate-buffered saline (PBS), with a linear detection range spanning 100 to 107 CFU/mL. In real samples, the sensor achieved detection limits of 5 CFU/mL in milk and 3 CFU/mL in chicken, with a linear detection range spanning 100 to 106 CFU/mL, maintaining high accuracy and reproducibility. The biosensor also effectively discriminated between live and dead bacterial cells, demonstrating its potential in real-world food safety applications. The biosensor performed excellently over a wide pH range (4–10) and remained stable for up to six weeks. Overall, the developed BC/Ppy/RGO–phage biosensor offers a promising tool for the rapid, sensitive, and selective detection of S. typhimurium, with robust performance across different food matrices.

5 September 2023 in Molecules
Verified
Journal Article
Open access
PDF file
SLSelsabil Rokia Laraba
Selsabil Rokia Laraba
NUNajeeb Ullah
Najeeb Ullah
ABAmirouche Bouamer
Amirouche Bouamer
Asmat UllahAsmat Ullah
Asmat Ullah
TATariq Aziz
Tariq Aziz
YLYulin Li
Yulin Li
Graphene has attracted extensive attention in various fields due to its intriguing properties. In this work, nanocomposite films based on poly(lactic acid) (PLA and PLLA) polymers filled with graphene oxide (GO) were developed. The impact of treating GO with the anionic surfactant dioctyl sulfosuccinate sodium salt (AOT) on the properties of the resulting nanocomposites was investigated. To determine the morphological, optical, and structural properties of the obtained materials, physicochemical analyses were performed, including scanning electron microscopy (SEM), atomic force microscopy (AFM), Fourier-transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) analysis. Additionally, the thermal properties and wettability of neat polymers and nanocomposites were thoroughly investigated using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and contact angle analysis. It was observed that GO was well dispersed throughout the PLA and PLLA matrix, leading to stronger interface bonding. The results demonstrate that the untreated and treated GO improved the crystallinity and thermal stability properties of the PLA and PLLA. However, the AOT-treated GO has significantly higher performance compared to the untreated GO in terms of crystallinity, melting temperature (increased by ~15 °C), and wettability (the contact angle decreased by ~30°). These findings reveal the high performance of the developed novel composite, which could be applied in tissue engineering as a scaffold.