Saravanan Krishnan

Dr. Saravanan Krishnan

Dhanvantari Nano Ayushadi Pvt Ltd
orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 November 2020 in Emergent Materials
Verified
Journal Article
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BJBlessy Joseph
Blessy Joseph
Saravanan KrishnanSaravanan Krishnan
Saravanan Krishnan
VSV. K. Sagarika
V. K. Sagarika
ATAbhimanyu Tharayil
Abhimanyu Tharayil
NKNandakumar Kalarikkal
Nandakumar Kalarikkal
STSabu Thomas
Sabu Thomas

3 July 2022 in Nanomaterials
Verified
Journal Article
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FYFaten Eshrati Yeganeh
Faten Eshrati Yeganeh
AYAmir Eshrati Yeganeh
Amir Eshrati Yeganeh
BFBahareh Farasati Far
Bahareh Farasati Far
AMafsoon Mansoori
afsoon Mansoori
BSBELAY ZELEKE SIBUH
BELAY ZELEKE SIBUH
Piyush Kumar GuptaPiyush Kumar Gupta
Piyush Kumar Gupta
In the present study, nickel ferrite (NiFe2O4)-based smart magnetic nanoparticles were fabricated and coated with methionine. Physiochemical characterization of the obtained Met-NiFe2O4 nanoparticles revealed the presence of methionine coating over the nanoparticle surface. Drug release study indicated that Tet-Met-NiFe2O4 nanoparticles possess pH-responsive controlled drug release behavior for tetracycline (Tet). The drug loading content for Tet was found to be 0.27 mg/L of nanoparticles. In vitro cytotoxicity test showed that the Met-NiFe2O4 nanoparticles is biocompatible. Moreover, this magnetic nanostructured material shown strong anticancer property as these nanomaterials significantly reduced the viability of A375 cells when compared to free Tet solution. In addition, Tet-Met-NiFe2O4 nanoparticles also showed strong antibacterial activity against different bacterial pathogens.

6 January 2021 in New Journal of Chemistry
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Journal Article
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Saravanan KrishnanSaravanan Krishnan
Saravanan Krishnan
PPParesh N Patel
Paresh N Patel
KBKalpattu K. Balasubramanian
Kalpattu K. Balasubramanian
ACAnju Chadha
Anju Chadha
Candida parapsilosis ATCC 7330 supported gold nanoparticles (CpGNP), prepared by a simple and green method can selectively reduce nitroarenes and substituted nitroarenes with different functional groups like halides (–F, –Cl, –Br), olefins, esters and nitriles using sodium borohydride. The product aryl amines which are useful for the preparation of pharmaceuticals, polymers and agrochemicals were obtained in good yields (up to >95%) using CpGNP catalyst under mild conditions. The catalyst showed high recyclability (≥10 cycles) and is a robust free flowing powder, stored and used after eight months without any loss in catalytic activity.

9 April 2021 in Sustainable Chemistry
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Journal Article
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BJBlessy Joseph
Blessy Joseph
Saravanan KrishnanSaravanan Krishnan
Saravanan Krishnan
SKSagarika V K
Sagarika V K
Avinash R PaiAvinash R Pai
Avinash R Pai
JJJemy James
Jemy James
STSabu Thomas
Sabu Thomas
Solvents are an inevitable part of industries. They are widely used in manufacturing and processing industries. Despite the numerous controlling measures taken, solvents contaminate our environment to a vast extent. Green and sustainable solvents have been a matter of growing interest within the research community over the past few years due to the increasing environmental concerns. Solvents are categorized as “green” based on their nonvolatility, nonflammability, availability, biodegradability and so on. The use of ionic liquids, super critical carbon dioxide and aqueous solvents for the fabrication of polymer composites is discussed in this review. The progress of utilizing solvent-free approaches for polymer composite preparation and efforts to produce new biobased solvents are also summarized.

29 June 2021 in Journal of Materials Chemistry B
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Saravanan KrishnanSaravanan Krishnan
Saravanan Krishnan
ADApurva Dusane
Apurva Dusane
RMRasmi Morajkar
Rasmi Morajkar
AVAkila Venkat
Akila Venkat
AVAmit A. Vernekar
Amit A. Vernekar
This review article discusses the role of nanomaterials and their future perspectives in the point-of-care diagnostics of COVID-19.

7 October 2016 in AMB Express
Verified
Journal Article
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Saravanan KrishnanSaravanan Krishnan
Saravanan Krishnan
SNShoba Narayan
Shoba Narayan
ACAnju Chadha
Anju Chadha
The cell free extracts of Candida parapsilosis ATCC 7330 are more efficient than the whole resting cells of the yeast in the synthesis of directly usable gold nanoparticles as revealed by this systematic study. Cell free extracts yielded gold nanoparticles of hydrodynamic diameter (50–200 nm). In this study, the total protein concentration influences the nanofabrication and not only the reductase enzymes as originally thought. Powder X-ray diffraction studies confirm the crystalline nature of the gold nanoparticles. Fourier Transform Infra Red spectroscopy and thermal gravimetric analysis suggests that the biosynthesized gold nanoparticles are capped by peptides/proteins. Dispersion experiments indicate a stable dispersion of gold nanoparticles in pH 12 solutions which is also confirmed by electron microscopic analysis and validated using a surface plasmon resonance assay. The effectiveness of the dispersed nanoparticles for the reduction of 4-nitrophenol using sodium borohydride as a reductant further confirms the formation of functional gold nanoparticles. It is also reported that gold nanoparticles with mean particle diameter of 27 nm are biosynthesized inside the whole cell by transmission electron microscopy analysis. With optimized reaction conditions, maximum gold bioaccumulation with the 24 h culture age of the yeast with cellular uptake of ~1010 gold atoms at the single cell level is achieved but it is not easy to extract the gold nanoparticles from the whole resting cells.