Ekene Ezenduka

Dr. Ekene Ezenduka

orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 April 2021 in Foods
Verified
Journal Article
Open access
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Emmanuel O. NjogaEmmanuel O. Njoga
Emmanuel O. Njoga
EEEkene Ezenduka
Ekene Ezenduka
COChiazor G. Ogbodo
Chiazor G. Ogbodo
COChukwuka Ogbonna
Chukwuka Ogbonna
Ishmael JajaIshmael Jaja
Ishmael Jaja
Charles Odilichukwu R. OkpalaCharles Odilichukwu R. Okpala
Charles Odilichukwu R. Okpala
Notwithstanding the increased toxic heavy metals/metalloids (THMs) accumulation in (edible) organs owed to goat′s feeding habit and anthropogenic activities, the chevon remains increasingly relished as a special delicacy in Nigeria. Specific to the South-Eastern region, however, there is paucity of relevant data regarding the prevalence of THMs in goat carcasses processed for human consumption. This work was, therefore, aimed to investigate the detection, distribution and health risk assessment of THMs in goat carcass processed for human consumption in South-Eastern Nigeria. To achieve this, a total of 450 meat samples (kidney, liver and muscle) were evaluated from 150 randomly selected goat carcasses processed in two major slaughterhouses in Enugu State. The detection, distribution, as well as health risk assessment parameters followed standard procedures. Results revealed that at least one THM was detected in 56% of the carcasses. Mean concentrations of arsenic (As) were 0.53 ± 0.10 mg/kg, 0.57 ± 0.09 mg/kg and 0.45 ± 0.08 mg/kg, lead (Pb) were 0.48 ± 0.38 mg/kg, 0.45 ± 0.24 mg/kg and 0.82 ± 0.39 mg/kg, cadmium (Cd) was 0.06 ± 0.32 mg/kg, 0.02 ± 0.00 mg/kg, and 0.02 ± 0.00 mg/kg for kidney, liver and muscle tissues, respectively. The estimated daily intakes (EDI) for all THMs were above the recommended safe limits. The target hazard quotient (THQ) and hazard index (HI) computed for all As, Cd and Pb fell below unity in all the studied organs, which indicated no non-carcinogenic risks. Curtailing the anthropogenic activities that aid the THM-contamination in goat production/processing lines is recommended. Screening for THM-contamination in Nigerian slaughterhouses is imperative, so as to ascertain the toxicological safety of meats intended for human consumption.

28 November 2016 in Veterinary World
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Journal Article
Open access
OOO. Josephine Okorie-Kanu
O. Josephine Okorie-Kanu
EEEkene Ezenduka
Ekene Ezenduka
COC. Onwuchokwe Okorie-Kanu
C. Onwuchokwe Okorie-Kanu
LUL. Chinweokwu Ugwu
L. Chinweokwu Ugwu
UNU. John Nnamani
U. John Nnamani
This study was conducted to investigate the occurrence of pathogenic Escherichia coli and Salmonella species in retail raw table eggs sold for human consumption in Enugu State and to determine the resistance of these pathogens to antimicrobials commonly used in human and veterinary practices in Nigeria. A total of 340 raw table eggs comprising 68 composite samples (5 eggs per composite sample) were collected from five selected farms (13 composite samples from the farms) and 10 retail outlets (55 composite samples from the retail outlets) in the study area over a period of 4-month (March-June, 2014). The eggs were screened for pathogenic E. coli and Salmonella species following standard procedures within 24 h of sample collection. Isolates obtained were subjected to in-vitro antimicrobial susceptibility test with 15 commonly used antimicrobials using the disk diffusion method. About 37 (54.4%) and 7 (10.3%) of the 68 composite samples were positive for pathogenic E. coli and Salmonella species, respectively. The shells showed significantly higher (p0.05). The organisms obtained showed a multiple drug resistance. They were completely resistant to nitrofurantoin, sulfamethoxazole/trimethoprim, penicillin G and oxacillin. In addition to these, Salmonella spp. also showed 100% resistance to tetracycline. The pathogenic E. coli isolates obtained were 100% susceptible to gentamicin, neomycin, ciprofloxacin, and amoxicillin-clavulanic acid while Salmonella spp. showed 100% susceptibility to erythromycin, neomycin, and rifampicin. Both organisms showed varying degrees of resistance to streptomycin, amoxicillin, vancomycin, and doxycycline. From the results of the study, it can be concluded that the raw table eggs marketed for human consumption in Enugu State, Nigeria is contaminated with pathogenic E. coli and Salmonella species that showed multiple drug resistance to antimicrobial agents commonly used in veterinary and human practice.

17 August 2018 in Veterinary World
Verified
Journal Article
Open access
OOOnyinye Josephine Okorie-Kanu
Onyinye Josephine Okorie-Kanu
EEEkene Ezenduka
Ekene Ezenduka
COChristian Onwuchokwe Okorie-Kanu
Christian Onwuchokwe Okorie-Kanu
CAChidiebere Ohazuruike Anyaoha
Chidiebere Ohazuruike Anyaoha
CAChukwuebuka Anselm Attah
Chukwuebuka Anselm Attah
SOS. Onyinye Onwumere-Idolor
S. Onyinye Onwumere-Idolor
This study was conducted to determine the incidence rate of the slaughter of pregnant goats in Nsukka slaughterhouse, which has become a major cruel occurrence in Nigeria

10 February 2018 in Veterinary World
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Journal Article
Open access
EEEkene Ezenduka
Ekene Ezenduka
OOOnyinye Josephine Okorie-Kanu
Onyinye Josephine Okorie-Kanu
NANwanta John Anaelom
Nwanta John Anaelom
The objective of this study was to determine the effect of varying temperatures (different cooking methods and freezing) on the concentration of oxytetracycline (OTC) residues in tissues of broiler birds

12 March 2020 in Veterinary World
Verified
Journal Article
Open access
OSOnwumere-Idolor Onyinye Stella
Onwumere-Idolor Onyinye Stella
EEEkene Ezenduka
Ekene Ezenduka
NANwanta John Anaelom
Nwanta John Anaelom
Background and Aim: Milk is a food that contains almost all the essential nutrients needed for growth and maintenance for both young and old animals and man. Since quite nutritious and in high demand, dairy products should be free of both chemical and biological contaminants. Unfortunately, antibiotics used in the treatment of infectious diseases in dairy cattle are often seen in their products if withdrawal periods of those drugs are not observed before milking. This study aimed to detect the presence of antibiotics and the level of tylosin in fresh and fermented (nono) milk from cows in Delta state, Nigeria. Materials and Methods: Two hundred and five samples comprising 126 fresh milk and 79 fermented milk (nono) were sampled from Kwale, Ozoro, and Oleh representing one senatorial district of Delta state, South-South Nigeria. They were screened for the presence of tylosin and other antimicrobial residues using four-plate test and tylosin was confirmed with high-performance liquid chromatography. Results: Antibiotic residues were obtained in 76% and 85% of fresh milk and nono, respectively. Tylosin residue was also detected in 24% fresh milk and 11% nono samples at mean concentrations of 14.64±0.69 μg/l and 7.97±0.23 μg/l, respectively. The mean concentrations of tylosin from both milk types were below the recommended maximum residue limit (MRL) of 50 μg/l in dairy. Conclusion: High prevalence of antimicrobial residues in fresh milk and nono shows that consumers in the study area are predisposed to health hazards due to the presence of residues of different antibiotics in fresh milk and nono. Although tylosin was confirmed in both milk products, the mean concentrations were below the MRL. However, it is still very vital to resort to the observance of withdrawal periods and avoid gross misuse of antimicrobials. It is also necessary to emphasize the need for effective prevention of infectious diseases and most importantly create awareness and establish a national antibiotic residue monitoring program in Nigeria.

31 May 2019 in Veterinary World
Verified
Journal Article
Open access
Ukamaka EzeUkamaka Eze
Ukamaka Eze
IEIkenna O. Ezeh
Ikenna O. Ezeh
TNTerry A. Nzeakor
Terry A. Nzeakor
SASamuel C. Attama
Samuel C. Attama
EEEkene Ezenduka
Ekene Ezenduka
DODenchris N. Onah
Denchris N. Onah
Aims: Cryptosporidiosis is an important zoonotic disease of major public and veterinary concern. The disease affects humans and a variety of animal species including the domestic dog. This study aimed to determine the prevalence and risk factors associated with Cryptosporidium spp. infection in local breed of dogs from different homes and those presented at veterinary hospitals and clinics in Enugu State, Nigeria. Materials and Methods: A total of 203 fresh fecal samples were collected from domestic dogs in six local government areas in Enugu State from February 2015 to August 2015. All the samples were examined using the formol-ether sedimentation method. Fecal smears were then stained by the modified Ziehl-Neelsen technique and examined under direct light microscopy. Results: A total of 74 (36.5%) dogs were infected with Cryptosporidium spp. oocysts. There was a strong association (p0.05) between the presence of Cryptosporidium spp. oocysts and age, sex, and fecal consistency. Conclusion: The findings of this work suggest that domestic dogs in Enugu State harbor and shed Cryptosporidium spp. oocysts in the environment, especially those managed semi-intensively. Such fecal shedding is particularly so and of greater zoonotic and epidemiological importance in animals that do not show clinical signs and therefore not treated. They, therefore, pose a greater public health risk, especially to immune-compromised humans and animals. Public education on the zoonotic implication of this protozoan infection is of paramount importance in Enugu State, in particular, and Nigeria, in general, considering the closeness of dogs and man.