Wearable dry electrodes are needed for long-term biopotential recordings but are limited by their imperfect compliance with the skin, especially during body movements and sweat secretions, resulting in high interfacial impedance and motion artifacts. Herein, we report an intrinsically conductive polymer dry electrode with excellent self-adhesiveness, stretchability, and conductivity. It shows much lower skin-contact impedance and noise in static and dynamic measurement than the current dry electrodes and standard gel electrodes, enabling to acquire high-quality electrocardiogram (ECG), electromyogram (EMG) and electroencephalogram (EEG) signals in various conditions such as dry and wet skin and during body movement. Hence, this dry electrode can be used for long-term healthcare monitoring in complex daily conditions. We further investigated the capabilities of this electrode in a clinical setting and realized its ability to detect the arrhythmia features of atrial fibrillation accurately, and quantify muscle activity during deep tendon reflex testing and contraction against resistance.

Flexible and stretchable tactile sensors that are printable, nonplanar, and dynamically morphing are emerging to enable proprioceptive interactions with the unstructured surrounding environment. Owing to its varied range of applications in the field of wearable electronics, soft robotics, human-machine interaction, and biomedical devices, it is required of these sensors to be flexible and stretchable conforming to the arbitrary surfaces of their stiff counterparts. The challenges in maintaining the fundamental features of these sensors, such as flexibility, sensitivity, repeatability, linearity, and durability, are tackled by the progress in the fabrication techniques and customization of the material properties. This review is aimed at summarizing the recent progress of rapid prototyping of sensors, printable material preparation, required printing properties, flexible and stretchable mechanisms, and promising applications and highlights challenges and opportunities in this research paradigm.

Origami-based flexible, compliant, and bio-inspired robots are believed to permit a range of medical applications within confined environments. In this article, we experimentally demonstrated an origami-inspired deployable surgical retractor with the controllable stiffness mechanism that can facilitate safer instrument–tissue interaction in comparison to their rigid counterparts. When controllable negative-pressure is applied to the jammed origami retractor module, it becomes more rigid, increasing its strength. To quantify origami-modules strength further, we demonstrated performances of retractor based on the Daler–Rowney Canford paper (38 grams per square meter (gsm)) and sandpaper of 1000 grit. Experiments on the proposed retractor prototype elucidated sandpaper-based retractor can outperform paper-38-gsm retractor for facelift incision with the width of more than 9 cm. Though 38 gsm Canford paper comprised of thin layers, 16 times lesser in thickness than sandpaper, experiments proved its comparable layer jamming (LJ) performance. We leverage the advantage of the LJ mechanism to tune retractor stiffness, allowing the instrument to hold and separate a facelift incision to mitigate the likelihood of surgical complications. The retractor is equipped with a custom-made printed conductive ink-based fabric piezoresistive tactile sensor to assist clinicians with tissue-retractor interaction force information. The proposed sensor showed a linear relationship with the applied force and has a sensitivity of 0.833 N−1. Finally, cadaver experiments exhibit an effective origami-inspired surgical retractor for assisting surgeons and clinicians in the near future.

Intra-abdominal pressure (IAP) is closely correlated with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) diagnoses, indicating the need for continuous monitoring. Early intervention for IAH and ACS has been proven to reduce the rate of morbidity. However, the current IAP monitoring method is a tedious process with a long calibration time for a single time point measurement. Thus, there is the need for an efficient and continuous way of measuring IAP. Herein, a stretchable capacitive pressure sensor with controlled microstructures embedded into a cylindrical elastomeric mold, fabricated as a pressure sensing sleeve, is presented. The sensing sleeve can be readily deployed onto intrabody catheter balloons for pressure measurement at the site. The thin and highly conformable nature of the pressure sensing sleeve captures the pressure change without hindering the functionality of the foley catheter balloon.

This paper presents a robotic needle positioning approach with a novel 4-DoF parallel positioner, two back-driveable 2-channel linear/rotational driver, and a machine-body interface. Being more compact and flexible, Ni-Ti alloy wire-based Bowden cable transmission is introduced to connect the positioner and the drivers. For this new mechanism, forward and inverse kinematics are derived, and the workspace is analyzed. The mechanism's maximum incidence angle is 45°, and the stroke of the slider is 41 mm. The structural size of one positioner is ø70 mm×45 mm. The compact size and lightweight of the positioner makes it readily mountable on the skull or attached to other parts of the body. We fabricated a 3D printed proof-of-concept prototype of the system and tested its performance. The open-loop positioning accuracy of the slider and rotor is within ±1 mm and -0.8°to 1.5°, respectively. The trajectory tracking error of the system is within 1.71 mm. The stiffness of the positioner in x and y directions can be calculated as 9.03 N/mm and 11.91 N/mm, respectively. Finally, an image-guided navigation framework based on electromagnetic tracking demonstrates the feasibility of the proposed system on a phantom study.