Biodegradable Mg–Zn–Ca-based metallic glasses (MGs) present improved strength and superior corrosion resistance, compared to crystalline Mg. In particular, in vivo and in vitro attempts reveal that biodegradable Mg–Zn–Ca-based MGs possess excellent biocompatibility, suggesting that they are ideal candidates for temporary implant materials. However, the limited size and severe brittleness prevent their widespread commercialization. In this review, we firstly summarize the microstructure characteristic and mechanical properties of Mg–Zn–Ca-based MGs. Then, we provide a comprehensive and systematic understanding of the recent progress of the biocorrosion and biocompatibility of Mg–Zn–Ca-based MGs. Last, but not least, the outlook towards the fabrication routes, composition design, structure design, and reinforcement approaches of Mg–Zn–Ca-based MGs are briefly proposed.

The morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD) is increasing year by year. Cortex Moutan is a traditional Chinese medicinal herb that has been widely used for thousands of years to treat a wide variety of diseases in Eastern countries due to its heat-clearing and detoxifying effects. Paeonol is a bioactive monomer extracted from Cortex Moutan, which has anti-atherosclerotic effects. In this article, we reviewed the pharmacological effects of paeonol against experimental atherosclerosis, as well as its protective effects on vascular endothelial cells, smooth muscle cells, macrophages, platelets, and other important cell types. The pleiotropic effects of paeonol in atherosclerosis suggest that it can be a promising therapeutic agent for atherosclerosis and its complications. Large-scale randomized clinical trials are warranted to elucidate whether paeonol are effective in patients with ASCVD.

The effect of the addition of bismuth on the dynamic recrystallization (DRX) behavior of the matrix has been investigated by comparing coarse grain pure Mg with the addition of 3 wt.% Bi, using a uniaxial compression test in the temperature range of 473–623 K and the strain rate of 0.01–10 s⁻¹. The constitutive equation, processing map, microstructure, and texture evolution of the Mg-3Bi alloy were systematically investigated. The results showed that the Bi addition could refine the grain size and accelerate the DRX process. The DRX kinetics is discussed in detail, accompanied by extensive characterization employing EBSD analysis. The DRX of the Mg-3Bi alloy depended on the deformation temperature rather than the strain rate. The {10–12} tensile twin appeared at 573 K/0.01–0.1 s⁻¹, and discontinuous DRX (DDRX), continuous DRX (CDRX) as the main mechanism in the case of 573 K/0.01 s⁻¹, while the dominant mechanism was DDRX when deformation temperature and strain rate increased. Particle-stimulated nucleation (PSN) was also involved in the DRX of this new RE-free Mg alloy.