Face scans are currently used in dentistry to obtain a virtual patient. Find stable and repeatable references for their matching is a fundamental step. Aim of this study is to evaluate matching reliability of multiple face scans using frontal adhesives references. Null hypothesis was that no significant discrepancy could be detected between the references position analyzed both with surface analysis and linear analysis. Nine patients were enrolled for this study and nine soft tissue adhesives landmarks (APLI Paper S.A.U, 4 mm Ø) placed, equally distributed, on the forehead and glabella. Patients were digitally scanned with a portable scanner (iPad Pro 3rd Gen. Apple Store, Cupertino, CA, USA) using the software Bellus3D (Inc. Campbell, CA, USA) in maximum intercuspation, with a full smile and with a scan reference device. After the scan procedure, a high-definition polygon file format (.ply) was exported, and linear measurements were collected with MeshLab (MeshLab; MeshLab). In order to further evaluate reference accuracy, a surface analysis was performed using a CAD software (GOM inspect, GOM). 3D deviations were calculated as root mean square. Statistical analysis was performed used two repeated-measures ANOVAs. Results showed non-significant differences both for linear measurements (p=.22) and surface analysis (p=.58). Frontal references showed to be clinical reliable landmarks for use during face scans alignment, even with different facial expressions. The proposed technique seems to be suitable for the clinical use when superimposition of several face scans is required. This study showed the clinical reliability of face scans matching method using adhesives references. These references are cheap and easy to use, allowing for a rapid registration of the patient anatomy.

Dentoalveolar surgery is probably the major risk factor for MRONJ and for other complications following a tooth extraction, especially in patients affected by systemic diseases. The aim of this retrospective study is to evaluate whether a PRF plug inserted in the post extraction socket can prevent the onset of MRONJ. The patients were divided into two groups according to the surgical protocol that included the insertion or not of the PRF following the extraction and all the anamnestic, and clinical data were analyzed. In the control group, 5 patients developed MRONJ (19.23%) while in the study group, any case of MRONJ was reported. In the control group, patients who developed MRONJ had a CTX with less than 100 pg/mL (5 high‐risk patients, Spearman’s rank r = .547, p < .001). The use of platelet concentrates in patients with high risk of MRONJ is a user‐friendly technique with an excellent cost‐benefit ratio in oral surgery.

The use of dental implants has grown over the years and has led to higher success rates. To further enhance surgical outcomes, many research groups and companies have shifted their focus to surfaces roughness, wettability and chemistry. In a recent study a new dry salt bioactivate surface has been described from a chemical and physical point of view. The aim of this study is to evaluate the osteogenic response of pre-osteoblast cell lines to dry bioactivated surface. MC3T3-E1 osteogenic cell lines were cultured on SM (sandblasted and dual acid-etched surface) and HNS (SM surface with dry salts bioactive technology). Cell adhesion assay, proliferation assay and cell morphology were performed. Osteogenic activity was performed using Alizarin Red S and alkaline phosphatase. The results showed that SM surface determines a slighter but significant increase in cell adhesion and proliferation in a shorter time compared to HNS. On the contrary, HNS surface has long and intertwining filopodia that could be a response to surface HNS-topography that results in a higher stage of differentiation. The nature of the HNS surface is more prone to determine massive deposition of calcium minerals. This study is the first investigating the role of this interesting dry-salts bioactive surface during the first phase of healing and its potential biochemical advantage could be validated by future animal studies with the aim of evaluate the rate of bone implant contact in the early stages of healing.

The surface topography of dental implants plays an important role in cell-surface interaction promoting cell adhesion, proliferation and differentiation influencing osseointegration. A hydrophilic implant leads to the absorption of water molecules and subsequently promotes the adhesion of cells to the implant binding protein. Dried salts on the implant surfaces allow one to store the implant surfaces in a dry environment while preserving their hydrophilic characteristics. This process has been identified as “dry technology”. The aim of the present study is to describe from a micrometric and nanometric point of view the characteristics of this new bioactivated surface obtained using salts dried on the surface. Topographic analysis, energy-dispersive X-ray spectroscopy, and contact angle characterization were performed on the samples of a sandblasted and dual acid-etched surface (ABT), a nanosurface (Nano) deriving from the former but with the adding of salts air dried and a nanosurface with salts dissolved with distilled water (Nano H₂O). The analysis revealed promising results for nanostructured surfaces with increased wettability and a more articulated surface nanotopography than the traditional ABT surface. In conclusion, this study validates a new promising ultra-hydrophilic nano surface obtained by sandblasting, double acid etching and surface salt deposition using dry technology.