Azham Zulkharnain

Dr. Azham Zulkharnain

Shibaura Institute of Technology
orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 January 2022 in Materials
Verified
Journal Article
Open access
ANAshwini Naganthran
Ashwini Naganthran
GVGayathiri Verasoundarapandian
Gayathiri Verasoundarapandian
FKFarah Eryssa Binti Ahmad Saiful Khalid
Farah Eryssa Binti Ahmad Saiful Khalid
MMMas Jaffri Masarudin
Mas Jaffri Masarudin
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
Siti Aqlima AhmadSiti Aqlima Ahmad
Siti Aqlima Ahmad
Silver nanoparticles (AgNPs) have been employed in various fields of biotechnology due to their proven properties as an antibacterial, antiviral and antifungal agent. AgNPs are generally synthesized through chemical, physical and biological approaches involving a myriad of methods. As each approach confers unique advantages and challenges, a trends analysis of literature for the AgNPs synthesis using different types of synthesis were also reviewed through a bibliometric approach. A sum of 10,278 publications were analyzed on the annual numbers of publication relating to AgNPs and biological, chemical or physical synthesis from 2010 to 2020 using Microsoft Excel applied to the Scopus publication database. Furthermore, another bibliometric clustering and mapping software were used to study the occurrences of author keywords on the biomedical applications of biosynthesized AgNPs and a total collection of 224 documents were found, sourced from articles, reviews, book chapters, conference papers and reviews. AgNPs provides an excellent, dependable, and effective solution for seven major concerns: as antibacterial, antiviral, anticancer, bone healing, bone cement, dental applications and wound healing. In recent years, AgNPs have been employed in biomedical sector due to their antibacterial, antiviral and anticancer properties. This review discussed on the types of synthesis, how AgNPs are characterized and their applications in biomedical field.

Verified
Journal Article
Open access
PDF file
FKFarah Eryssa Binti Ahmad Saiful Khalid
Farah Eryssa Binti Ahmad Saiful Khalid
Zheng Syuen LimZheng Syuen Lim
Zheng Syuen Lim
Suriana SabriSuriana Sabri
Suriana Sabri
CGClaudio Gómez-Fuentes
Claudio Gómez-Fuentes
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
Siti Aqlima AhmadSiti Aqlima Ahmad
Siti Aqlima Ahmad
Oil pollution can cause tremendous harm and risk to the water ecosystem and organisms due to the relatively recalcitrant hydrocarbon compounds. The current chemical method used to treat the ecosystem polluted with diesel is incompetent and expensive for a large-scale treatment. Thus, bioremediation technique seems urgent and requires more attention to solve the existing environmental problems. Biological agents, including microorganisms, carry out the biodegradation process where organic pollutants are mineralized into water, carbon dioxide, and less toxic compounds. Hydrocarbon-degrading bacteria are ubiquitous in the nature and often exploited for their specialty to bioremediate the oil-polluted area. The capability of these bacteria to utilize hydrocarbon compounds as a carbon source is the main reason behind their species exploitation. Recently, microbial remediation by halophilic bacteria has received many positive feedbacks as an efficient pollutant degrader. These halophilic bacteria are also considered as suitable candidates for bioremediation in hypersaline environments. However, only a few microbial species have been isolated with limited available information on the biodegradation of organic pollutants by halophilic bacteria. The fundamental aspect for successful bioremediation includes selecting appropriate microbes with a high capability of pollutant degradation. Therefore, high salinity bacteria are remarkable microbes for diesel degradation. This paper provides an updated overview of diesel hydrocarbon degradation, the effects of oil spills on the environment and living organisms, and the potential role of high salinity bacteria to decontaminate the organic pollutants in the water environment.

2 May 2018 in Applied Bionics and Biomechanics
Verified
Journal Article
Open access
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MIMohd Danial Ibrahim
Mohd Danial Ibrahim
SAS. N. A. Amran
S. N. A. Amran
YYY. S. Yunos
Y. S. Yunos
MRM. R. A. Rahman
M. R. A. Rahman
MMM. Z. Mohtar
M. Z. Mohtar
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
The skin of a fast swimming shark reveals riblet structures that help reduce the shark’s skin friction drag, enhancing its efficiency and speed while moving in the water. Inspired by the structure of the shark skin denticles, our team has carried out a study as an effort in improving the hydrodynamic design of marine vessels through hull design modification which was inspired by this riblet structure of shark skin denticle. Our study covers on macroscaled design modification. This is an attempt to propose an alternative for a better economical and practical modification to obtain a more optimum cruising characteristics for marine vessels. The models used for this study are constructed using computer-aided design (CAD) software, and computational fluid dynamic (CFD) simulations are then carried out to predict the effectiveness of the hydrodynamic effects of the biomimetic shark skins on those models. Interestingly, the numerical calculated results obtained show that the presence of biomimetic shark skin implemented on the vessels give about 3.75% reduction of drag coefficient as well as reducing up to 3.89% in drag force experienced by the vessels. Theoretically, as force drag can be reduced, it can lead to a more efficient vessel with a better cruising speed. This will give better impact to shipping or marine industries around the world. However, it can be suggested that an experimental procedure is best to be conducted to verify the numerical result that has been obtained for further improvement on this research.

20 December 2019 in Extremophiles
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Journal Article
Closed access
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ARAhmad Fareez Ahmad Roslee
Ahmad Fareez Ahmad Roslee
NZNur Nadhirah Zakaria
Nur Nadhirah Zakaria
PCPeter Convey
Peter Convey
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
Gillian Li Yin LeeGillian Li Yin Lee
Gillian Li Yin Lee
Siti Aqlima AhmadSiti Aqlima Ahmad
Siti Aqlima Ahmad

21 April 2020 in Antarctic Science
Verified
Journal Article
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MAMansur Abdulrasheed
Mansur Abdulrasheed
NZNur Nadhirah Zakaria
Nur Nadhirah Zakaria
ARAhmad Fareez Ahmad Roslee
Ahmad Fareez Ahmad Roslee
MSMohd Yunus Shukor
Mohd Yunus Shukor
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
Siti Aqlima AhmadSiti Aqlima Ahmad
Siti Aqlima Ahmad
Bioremediation has been proposed as a means of dealing with oil spills on the continent. However, the introduction of non-native organisms, including microbes, even for this purpose would appear to breach the terms of the Environmental Protocol to the Antarctic Treaty. This study therefore aimed to optimize the growth conditions and diesel degradation activity of the Antarctic native bacteria Arthrobacter spp. strains AQ5-05 and AQ5-06 through the application of a one-factor-at-a-time (OFAT) approach. Both strains were psychrotolerant, with the optimum temperature supporting diesel degradation being 10–15°C. Both strains were also screened for biosurfactant production and biofilm formation. Their diesel degradation potential was assessed using Bushnell–Haas medium supplemented with 0.5% (v/v) diesel as the sole carbon source and determined using both gravimetric and gas chromatography and mass spectrophotometry analysis. Strain AQ5-06 achieved 37.5% diesel degradation, while strain AQ5-05 achieved 34.5% diesel degradation. Both strains produced biosurfactants and showed high biofilm adherence. Strains AQ5-05 and AQ5-06 showed high cellular hydrophobicity rates of 73.0% and 81.5%, respectively, in hexadecane, with somewhat lower values of 60.5% and 70.5%, respectively, in tetrahexadecane. Optimized conditions identified via OFAT increased diesel degradation to 41.0% and 47.5% for strains AQ5-05 and AQ5-06, respectively. Both strains also demonstrated the ability to degrade diesel in the presence of heavy metal co-pollutants. This study therefore confirms the potential use of these cold-tolerant bacterial strains in the biodegradation of diesel-polluted Antarctic soils at low environmental temperatures.

22 April 2021 in Biology
Verified
Journal Article
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HOW SWEN YAPHOW SWEN YAP
HOW SWEN YAP
NADHIRAH ZAKARIANADHIRAH ZAKARIA
NADHIRAH ZAKARIA
Azham ZulkharnainAzham Zulkharnain
Azham Zulkharnain
Suriana SabriSuriana Sabri
Suriana Sabri
CGClaudio Gómez-Fuentes
Claudio Gómez-Fuentes
Siti Aqlima AhmadSiti Aqlima Ahmad
Siti Aqlima Ahmad
The increased usage of petroleum oils in cold regions has led to widespread oil pollutants in soils. The harsh environmental conditions in cold environments allow the persistence of these oil pollutants in soils for more than 20 years, raising adverse threats to the ecosystem. Microbial bioremediation was proposed and employed as a cost-effective tool to remediate petroleum hydrocarbons present in soils without significantly posing harmful side effects. However, the conventional hydrocarbon bioremediation requires a longer time to achieve the clean-up standard due to various environmental factors in cold regions. Recent biotechnological improvements using biostimulation and/or bioaugmentation strategies are reported and implemented to enhance the hydrocarbon removal efficiency under cold conditions. Thus, this review focuses on the enhanced bioremediation for hydrocarbon-polluted soils in cold regions, highlighting in situ and ex situ approaches and few potential enhancements via the exploitation of molecular and microbial technology in response to the cold condition. The bibliometric analysis of the hydrocarbon bioremediation research in cold regions is also presented.