Caterina Cinti

Dr. Caterina Cinti

Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council of Italy (CNR), Rome, Italy
orcid

Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 May 2002 in Journal of Cellular Physiology
Verified
Journal Article
Open access
PDF file
MMM. Macaluso
M. Macaluso
GRGiuseppe Russo
Giuseppe Russo
Caterina CintiCaterina Cinti
Caterina Cinti
VBV. Bazan
V. Bazan
NGN. Gebbia
N. Gebbia
ARA. Russo
A. Russo
Ras genes are evolutionary conserved and codify for a monomeric G protein binding GTP (active form) or GDP (inactive form). The ras genes are ubiquitously expressed although mRNA analysis suggests different level expression in tissue. Mutations in each ras gene frequently were found in different tumors, suggesting their involvement in the development of specific neoplasia. These mutations lead to a constitutive active and potentially oncogenic protein that could cause a deregulation of cell cycle. Ras protein moderates cellular responses at several mitogens and/or differentiation factors and at external stimuli. These stimuli activate a series of signal transduction pathways that either can be independent or interconnected at different points. Recent observations begin to clarify the complex relationship between Ras activation, apoptosis, and cellular proliferation. A greater understanding of these processes would help to identify the factors directly responsible for cell cycle deregulation in several tumors, moreover it would help the design of specific therapeutic strategies, for the control on the proliferation of neoplastic cells. We summarize here current knowledge of ras genes family: structural and functional characteristics of Ras proteins and their links with cell cycle and cancer.

5 June 2003 in Oncogene
Verified
Journal Article
Closed access
PDF file
MMMarcella Macaluso
Marcella Macaluso
Caterina CintiCaterina Cinti
Caterina Cinti
GRGiuseppe Russo
Giuseppe Russo
ARAntonio Russo
Antonio Russo
Antonio GiordanoAntonio Giordano
Antonio Giordano

Verified
Journal Article
Open access
LGLisa Gherardini
Lisa Gherardini
GCGastone Ciuti
Gastone Ciuti
STSelene Tognarelli
Selene Tognarelli
Caterina CintiCaterina Cinti
Caterina Cinti
There is a growing concern in the population about the effects that environmental exposure to any source of “uncontrolled” radiation may have on public health. Anxiety arises from the controversial knowledge about the effect of electromagnetic field (EMF) exposure to cells and organisms but most of all concerning the possible causal relation to human diseases. Here we reviewed those in vitro and in vivo and epidemiological works that gave a new insight about the effect of radio frequency (RF) exposure, relating to intracellular molecular pathways that lead to biological and functional outcomes. It appears that a thorough application of standardized protocols is the key to reliable data acquisition and interpretation that could contribute a clearer picture for scientists and lay public. Moreover, specific tuning of experimental and clinical RF exposure might lead to beneficial health effects.

25 October 2005 in Journal of Cellular Physiology
Verified
Journal Article
Closed access
PDF file
ARAnnalisa Roberti
Annalisa Roberti
DSDario La Sala
Dario La Sala
Caterina CintiCaterina Cinti
Caterina Cinti

1 March 2000 in The American Journal of Pathology
Verified
Journal Article
Closed access
Caterina CintiCaterina Cinti
Caterina Cinti
LLLorenzo Leoncini
Lorenzo Leoncini
ANAggrey Nyongo
Aggrey Nyongo
FFFilomena Ferrari
Filomena Ferrari
Stefano LazziStefano Lazzi
Stefano Lazzi
Antonio GiordanoAntonio Giordano
Antonio Giordano

1 June 2018 in Journal of Controlled Release
Verified
Journal Article
Closed access
RGRenata Grifantini
Renata Grifantini
Monia TarantaMonia Taranta
Monia Taranta
LGLisa Gherardini
Lisa Gherardini
INIlaria Naldi
Ilaria Naldi
MPMatteo Parri
Matteo Parri
Caterina CintiCaterina Cinti
Caterina Cinti