Breast cancer is a global cause for concern owing to its high incidence around the world. The alarming increase in breast cancer cases emphasizes the management of disease at multiple levels. The management should start from the beginning that includes stringent cancer screening or cancer registry to effective diagnostic and treatment strategies. Breast cancer is highly heterogeneous at morphology as well as molecular levels and needs different therapeutic regimens based on the molecular subtype. Breast cancer patients with respective subtype have different clinical outcome prognoses. Breast cancer heterogeneity emphasizes the advanced molecular testing that will help on‐time diagnosis and improved survival. Emerging fields such as liquid biopsy and artificial intelligence would help to under the complexity of breast cancer disease and decide the therapeutic regimen that helps in breast cancer management. In this review, we have discussed various risk factors and advanced technology available for breast cancer diagnosis to combat the worst breast cancer status and areas that need to be focused for the better management of breast cancer.

The electroencephalogram (EEG) signals are a big data which are frequently corrupted by motion artifacts. As human neural diseases, diagnosis and analysis need a robust neurological signal. Consequently, the EEG artifacts’ eradication is a vital step. In this research paper, the primary motion artifact is detected from a single-channel EEG signal using support vector machine (SVM) and preceded with further artifacts’ suppression. The signal features’ abstraction and further detection are done through ensemble empirical mode decomposition (EEMD) algorithm. Moreover, canonical correlation analysis (CCA) filtering approach is applied for motion artifact removal. Finally, leftover motion artifacts’ unpredictability is removed by applying wavelet transform (WT) algorithm. Finally, results are optimized by using Harris hawks optimization (HHO) algorithm. The results of the assessment confirm that the algorithm recommended is superior to the algorithms currently in use.

Image segmentation is a branch of digital image processing which has numerous applications in the field of analysis of images, augmented reality, machine vision, and many more. The field of medical image analysis is growing and the segmentation of the organs, diseases, or abnormalities in medical images has become demanding. The segmentation of medical images helps in checking the growth of disease like tumour, controlling the dosage of medicine, and dosage of exposure to radiations. Medical image segmentation is really a challenging task due to the various artefacts present in the images. Recently, deep neural models have shown application in various image segmentation tasks. This significant growth is due to the achievements and high performance of the deep learning strategies. This work presents a review of the literature in the field of medical image segmentation employing deep convolutional neural networks. The paper examines the various widely used medical image datasets, the different metrics used for evaluating the segmentation tasks, and performances of different CNN based networks. In comparison to the existing review and survey papers, the present work also discusses the various challenges in the field of segmentation of medical images and different state-of-the-art solutions available in the literature.

Diabetic retinopathy (DR) is a diabetes complication that affects the eye and can cause damage from mild vision problems to complete blindness. It has been observed that the eye fundus images show various kinds of color aberrations and irrelevant illuminations, which degrade the diagnostic analysis and may hinder the results. In this research, we present a methodology to eliminate these unnecessary reflectance properties of the images using a novel image processing schema and a stacked deep learning technique for the diagnosis. For the luminosity normalization of the image, the gray world color constancy algorithm is implemented which does image desaturation and improves the overall image quality. The effectiveness of the proposed image enhancement technique is evaluated based on the peak signal to noise ratio (PSNR) and mean squared error (MSE) of the normalized image. To develop a deep learning based computer-aided diagnostic system, we present a novel methodology of stacked generalization of convolution neural networks (CNN). Three custom CNN model weights are fed on the top of a single meta-learner classifier, which combines the most optimum weights of the three sub-neural networks to obtain superior metrics of evaluation and robust prediction results. The proposed stacked model reports an overall test accuracy of 97.92% (binary classification) and 87.45% (multi-class classification). Extensive experimental results in terms of accuracy, F-measure, sensitivity, specificity, recall and precision reveal that the proposed methodology of illumination normalization greatly facilitated the deep learning model and yields better results than various state-of-art techniques.

We live in a world where people are suffering from many diseases. Cancer is the most threatening of them all. Among all the variants of cancer, skin cancer is spreading rapidly. It happens because of the abnormal growth of skin cells. The increase in ultraviolet radiation on the Earth’s surface is also helping skin cancer spread in every corner of the world. Benign and malignant types are the most common skin cancers people suffer from. People go through expensive and time-consuming treatments to cure skin cancer but yet fail to lower the mortality rate. To reduce the mortality rate, early detection of skin cancer in its incipient phase is helpful. In today’s world, deep learning is being used to detect diseases. The convolutional neural network (CNN) helps to find skin cancer through image classification more accurately. This research contains information about many CNN models and a comparison of their working processes for finding the best results. Pretrained models like VGG16, Support Vector Machine (SVM), ResNet50, and self-built models (sequential) are used to analyze the process of CNN models. These models work differently as there are variations in their layer numbers. Depending on their layers and work processes, some models work better than others. An image dataset of benign and malignant data has been taken from Kaggle. In this dataset, there are 6594 images of benign and malignant skin cancer. Using different approaches, we have gained accurate results for VGG16 (93.18%), SVM (83.48%), ResNet50 (84.39%), Sequential_Model_1 (74.24%), Sequential_Model_2 (77.00%), and Sequential_Model_3 (84.09%). This research compares these outcomes based on the model’s work process. Our comparison includes model layer numbers, working process, and precision. The VGG16 model has given us the highest accuracy of 93.18%.