Breast cancer is a global cause for concern owing to its high incidence around the world. The alarming increase in breast cancer cases emphasizes the management of disease at multiple levels. The management should start from the beginning that includes stringent cancer screening or cancer registry to effective diagnostic and treatment strategies. Breast cancer is highly heterogeneous at morphology as well as molecular levels and needs different therapeutic regimens based on the molecular subtype. Breast cancer patients with respective subtype have different clinical outcome prognoses. Breast cancer heterogeneity emphasizes the advanced molecular testing that will help on‐time diagnosis and improved survival. Emerging fields such as liquid biopsy and artificial intelligence would help to under the complexity of breast cancer disease and decide the therapeutic regimen that helps in breast cancer management. In this review, we have discussed various risk factors and advanced technology available for breast cancer diagnosis to combat the worst breast cancer status and areas that need to be focused for the better management of breast cancer.
24 January 2021 in Archives of Computational Methods in Engineering
Image segmentation is a branch of digital image processing which has numerous applications in the field of analysis of images, augmented reality, machine vision, and many more. The field of medical image analysis is growing and the segmentation of the organs, diseases, or abnormalities in medical images has become demanding. The segmentation of medical images helps in checking the growth of disease like tumour, controlling the dosage of medicine, and dosage of exposure to radiations. Medical image segmentation is really a challenging task due to the various artefacts present in the images. Recently, deep neural models have shown application in various image segmentation tasks. This significant growth is due to the achievements and high performance of the deep learning strategies. This work presents a review of the literature in the field of medical image segmentation employing deep convolutional neural networks. The paper examines the various widely used medical image datasets, the different metrics used for evaluating the segmentation tasks, and performances of different CNN based networks. In comparison to the existing review and survey papers, the present work also discusses the various challenges in the field of segmentation of medical images and different state-of-the-art solutions available in the literature.
8 February 2022 in IEEE Journal of Biomedical and Health Informatics
Human skin disease, the most infectious dermatological ailment globally, is initially diagnosed by sight. Some clinical screening and dermoscopic analysis of skin biopsies and scrapings for accurate classification are medically compulsory. Classification of skin diseases using medical images is more challenging because of the complex formation and variant colors of the disease and data security concerns. Both the Convolution Neural Network (CNN) for classification and a federated learning approach for data privacy preservation show significant performance in the realm of medical imaging fields. In this paper, a custom image dataset was prepared with four classes of skin disease, a CNN model was suggested and compared with several benchmark CNN algorithms, and an experiment was carried out to ensure data privacy using a federated learning approach. An image augmentation strategy was followed to enlarge the dataset and make the model more general. The proposed model achieved a precision of 86%, 43%, and 60%, and a recall of 67%, 60%, and 60% for acne, eczema, and psoriasis. In the federated learning approach, after distributing the dataset among 1000, 1500, 2000, and 2500 clients, the model showed an average accuracy of 81.21%, 86.57%, 91.15%, and 94.15%. The CNN-based skin disease classification merged with the federated learning approach is a breathtaking concept to classify human skin diseases while ensuring data security.
20 December 2021 in Computational and Mathematical Methods in Medicine
Bone cancer is considered a serious health problem, and, in many cases, it causes patient death. The X-ray, MRI, or CT-scan image is used by doctors to identify bone cancer. The manual process is time-consuming and required expertise in that field. Therefore, it is necessary to develop an automated system to classify and identify the cancerous bone and the healthy bone. The texture of a cancer bone is different compared to a healthy bone in the affected region. But in the dataset, several images of cancer and healthy bone are having similar morphological characteristics. This makes it difficult to categorize them. To tackle this problem, we first find the best suitable edge detection algorithm after that two feature sets one with hog and another without hog are prepared. To test the efficiency of these feature sets, two machine learning models, support vector machine (SVM) and the Random forest, are utilized. The features set with hog perform considerably better on these models. Also, the SVM model trained with hog feature set provides an -score of 0.92 better than Random forest -score 0.77.
Dermoscopy images can be classified more accurately if skin lesions or nodules are segmented. Because of their fuzzy borders, irregular boundaries, inter- and intra-class variances, and so on, nodule segmentation is a difficult task. For the segmentation of skin lesions from dermoscopic pictures, several algorithms have been developed. However, their accuracy lags well behind the industry standard. In this paper, a modified U-Net architecture is proposed by modifying the feature map’s dimension for an accurate and automatic segmentation of dermoscopic images. Apart from this, more kernels to the feature map allowed for a more precise extraction of the nodule. We evaluated the effectiveness of the proposed model by considering several hyper parameters such as epochs, batch size, and the types of optimizers, testing it with augmentation techniques implemented to enhance the amount of photos available in the PH2 dataset. The best performance achieved by the proposed model is with an Adam optimizer using a batch size of 8 and 75 epochs.
About Me
Deepika Koundal is currently associated with the University of Petroleum and Energy Studies, Dehradun. She received recognition and an honorary membership from the Neutrosophic Science Association of the University of New Mexico, USA. She was also selected as a Young Scientist for the sixth BRICS Conclave in 2021. She received her Master's and Ph.D. degrees in Computer Science and Engineering from Panjab University, Chandigarh, in 2015. She received her B. Tech. degree in Computer Science and Engineering from Kurukshetra University, India. She is the awardee of a research excellence award given by Chitkara University in 2019. She has published more than 40 research articles in reputed SCI and Scopus-indexed journals and conferences, as well as two books.
Deepika Koundal is currently associated with the University of Petroleum and Energy Studies, Dehradun. She received recognition and an honorary membership from the Neutrosophic Science Association of the University of New Mexico, USA. She was also selected as a Young Scientist for the sixth BRICS Conclave in 2021. She received her Master's and Ph.D. degrees in Computer Science and Engineering from Panjab University, Chandigarh, in 2015. She received her B. Tech. degree in Computer Science and Engineering from Kurukshetra University, India. She is the awardee of a research excellence award given by Chitkara University in 2019. She has published more than 40 research articles in reputed SCI and Scopus-indexed journals and conferences, as well as two books.