In traditional hospital systems, diagnosis and localization of melanoma are the critical challenges for pathological analysis, treatment instructions, and prognosis evaluation particularly in skin diseases. In literature, various studies have been reported to address these issues; however, a prominent smart diagnosis system is needed to be developed for the smart healthcare system. In this study, a deep learning-enabled diagnostic system is proposed and implemented that it has the capacity to automatically detect malignant melanoma in whole slide images (WSIs). In this system, the convolutional neural network (CNN), sophisticated statistical method, and image processing algorithms were integrated and implemented to locate benign and malignant lesions which are extremely useful in the diagnoses process of melanoma disease. To verify the exceptional performance of the proposed scheme, it is implemented in a multicenter database, which has 701 WSIs (641 WSIs from Central South University Xiangya Hospital (CSUXH) and 60 WSIs from the Cancer Genome Atlas (TCGA)). Experimental results have verified that the proposed system has achieved an area under the receiver operating characteristic curve (AUROC) of 0.971. Furthermore, the lesion area on the WSIs is represented by its degree of malignancy. These results show that the proposed system has the capacity to fully automate the diagnosis and localization problem of the melanoma in the smart healthcare systems.

At present, deep learning-based medical image diagnosis had achieved high performance in several diseases. However, the black-box nature of the convolutional neural network (CNN) limits their role in diagnosis. In this study, a novel interpretable diagnosis pipeline using the CNN model was proposed. Furthermore, a sizeable melanoma database that contains 841 digital whole-slide images (WSIs) was built to train and evaluate the model. The model achieved strong melanoma classification ability (0.962 areas under the receiver operating characteristic, 0.887 sensitivity, and 0.925 specificity). Moreover, the proposed model outperformed the existing schemes in terms of accuracy that is 20 pathologists (0.933 vs 0.732 accuracy). Finally, the gradient-weighted class activation mapping (Grad-CAM) method was used to show the inner logic of the proposed model and its feasibility to improve diagnosis process in healthcare. The mechanism of feature heat maps which is visualized through a saliency mapping has demonstrated that features learned or extracted by the proposed model are compatible with the accepted pathological features. Conclusively, the proposed model provides a rapid and accurate diagnosis by locating the distinctive features of melanoma to build doctors trust in the CNNs diagnosis results.

The ever-expanding power system is developed into an interconnected pattern of power grids. Zone partitioning is an essential technique for the operation and management of such an interconnected power system. Owing to the transmission capacity limitation, transmission congestion may occur with a regional influence on power system. If transmission congestion is considered when the system is decomposed into several regions, the power consumption structure can be optimized and power system planning can be more reasonable. At the same time, power resources can be properly allocated and system safety can be improved. In this paper, we propose a power system zone partitioning method where the potential congested branches are identified and the spectral clustering algorithm is improved. We transform the zone partitioning problem into a graph segmentation problem by constructing an undirected weighted graph of power system where the similarities between buses are measured by the power transfer distribution factor (PTDF) corresponding to the potential congested branches. Zone partitioning results show that the locational marginal price (LMP) in the same zone is similar, which can represent regional price signals and provide regional auxiliary decisions.

Many previous works only focused on the cascading failure of global coupling of one-to-one structures in interdependent networks, but the local coupling of dual coupling structures has rarely been studied due to its complex structure. This will result in a serious consequence that many conclusions of the one-to-one structure may be incorrect in the dual coupling network and do not apply to the smart grid. Therefore, it is very necessary to subdivide the dual coupling link into a top-down coupling link and a bottom-up coupling link in order to study their influence on network robustness by combining with different coupling modes. Additionally, the power flow of the power grid can cause the load of a failed node to be allocated to its neighboring nodes and trigger a new round of load distribution when the load of these nodes exceeds their capacity. This means that the robustness of smart grids may be affected by four factors, i.e., load redistribution, local coupling, dual coupling link and coupling mode; however, the research on the influence of those factors on the network robustness is missing. In this paper, firstly, we construct the smart grid as a two-layer network with a dual coupling link and divide the power grid and communication network into many subnets based on the geographical location of their nodes. Secondly, we define node importance ( $NI$ ) as an evaluation index to access the impact of nodes on the cyber or physical network and propose three types of coupling modes based on $NI$ of nodes in the cyber and physical subnets, i.e., Assortative Coupling in Subnets (ACIS), Disassortative Coupling in Subnets (DCIS), and Random Coupling in Subnets (RCIS). Thirdly, a cascading failure model is proposed for studying the effect of local coupling of dual coupling link in combination with ACIS, DCIS, and RCIS on the robustness of the smart grid against a targeted attack, and the survival rate of functional nodes is used to assess the robustness of the smart grid. Finally, we use the IEEE 118-Bus System and the Italian High-Voltage Electrical Transmission Network to verify our model and obtain the same conclusions: (I) DCIS applied to the top-down coupling link is better able to enhance the robustness of the smart grid against a targeted attack than RCIS or ACIS, (II) ACIS applied to a bottom-up coupling link is better able to enhance the robustness of the smart grid against a targeted attack than RCIS or DCIS, and (III) the robustness of the smart grid can be improved by increasing the tolerance $\alpha$ . This paper provides some guidelines for slowing down the speed of the cascading failures in the design of architecture and optimization of interdependent networks, such as a top-down link with DCIS, a bottom-up link with ACIS, and an increased tolerance $\alpha$ .

Infrared small target detection (IRSTD) remains a critical yet challenging task due to the inherent low signal-to-noise ratio, weak target features, and complex backgrounds prevalent in infrared images. Existing methods often struggle to effectively capture the subtle edge features of targets and suppress background clutter simultaneously. To address these limitations, this study proposed a novel Multi-directional Learnable Edge-assisted Dense Nested Attention Network (MLEDNet). Firstly, we propose a multi-directional learnable edge extraction module (MLEEM), which is designed to capture rich directional edge information. The extracted multi-directional edge features are hierarchically integrated into the dense nested attention module (DNAM) to significantly enhance the model’s capability in discerning the crucial edge features of infrared small targets. Then, we design a feature fusion module guided by residual channel spatial attention (ResCSAM-FFM). This module leverages spatio-channel contextual cues to intelligently fuse features across different levels output by the DNAM, effectively enhancing target representation while robustly suppressing complex background interferences. By combining the MLEEM and the ResCSAM-FFM within a dense nested attention framework, we present a new model named MLEDNet. Extensive experiments conducted on benchmark datasets NUDT-SIRST and NUAA-SIRST demonstrate that the proposed MLEDNet achieves superior performance compared to state-of-the-art methods.