Objective: This article presents the development and validation of a new robotic system for Transcranial Magnetic Stimulation (TMS), characterized by a new control approach, and an ad-hoc calibration methodology, specifically devised for the TMS application. Methods: The robotic TMS platform is composed of a 7 dof manipulator, controlled by an impedance control, and a camera-based neuronavigation system. The proposed calibration method was optimized on the workspace useful for the specific TMS application (spherical shell around the subject's head), and tested on three different hand-eye and robot-world calibration algorithms. The platform functionality was tested on six healthy subjects during a real TMS procedure, over the left primary motor cortex. Results: employing our method significantly decreases ( $p< 0.001$ ) the calibration error by 34% for the position and 19% for the orientation. The robotic TMS platform achieved greater orientation accuracy than the expert operators, significantly reducing orientation errors by 46% ( $p< 0.001$ ). No significant differences were found in the position errors and in the amplitude of the motor evoked potentials (MEPs) between the robot-aided TMS and the expert operators. Conclusion: The proposed calibration represents a valid method to significantly reduce the calibration errors in robot-aided TMS applications. Results showed the efficacy of the proposed platform (including the control algorithm) in administering a real TMS procedure, achieving better coil positioning than expert operators, and similar results in terms of MEPs. Significance: This article spotlights how to improve the performance of a robotic TMS platform, providing a reproducible and low-cost alternative to the few devices commercially available.

The successful completion of complex tasks like hanging a picture or laparoscopic surgery requires coordinated motion of more than two limbs. User-controlled supernumerary robotic limbs (SL) have been proposed to bypass the need for coordination with a partner in such tasks. However, neither the capability to control multiple limbs alone relative to collaborative control with partners, nor how that capability varies across different tasks, is well understood. In this work, we present an investigation of tasks requiring three-hands where the foot was used as an additional source of motor commands. We considered: (1) how does simultaneous control of three hands compare to a cooperating dyad; (2) how this relative performance was altered by the existence of constraints emanating from real or virtual physical connections (mechanical constraints) or from cognitive limits (cognitive constraints). It was found that a cooperating dyad outperformed a single user in all scenarios in terms of task score, path efficiency and motion smoothness. However, while the participants were able to reach more targets with increasing mechanical constraints/decreasing number of simultaneous goals, the relative difference in performance between a dyad and a participant performing trimanual activities decreased, suggesting further potential for SLs in this class of scenario.

Bowing is the fundamental motor action responsible for sound production in violin playing. A lot of effort is required to control such a complex technique, especially at the beginning of violin training, also due to a lack of quantitative assessments of bowing movements. Here, we present magneto-inertial measurement units (MIMUs) and an optical sensor interface for the real-time monitoring of the fundamental parameters of bowing. Two MIMUs and a sound recorder were used to estimate the bow orientation and acquire sounds. An optical motion capture system was used as the gold standard for comparison. Four optical sensors positioned on the bow stick measured the stick–hair distance. During a pilot test, a musician was asked to perform strokes using different sections of the bow at different paces. Distance data were used to train two classifiers, a linear discriminant (LD) classifier and a decision tree (DT) classifier, to estimate the bow section used. The DT classifier reached the best classification accuracy (94.2%). Larger data analysis on nine violin beginners showed that the orientation error was less than 2°; the bow tilt correlated with the audio information $(r\left(134\right)=-0.973, 95\% \mathrm{CI} \left[-0.981,-0.962\right], p<0.001)$. The results confirmed that the interface provides reliable information on the bowing technique that might improve the learning performance of violin beginners.

In this paper we propose and validate a teleoperated control approach for an anthropomorphic redundant robotic manipulator, using magneto-inertial sensors (IMUs). The proposed method allows mapping the motion of the human arm (used as the master) on the robot end-effector (the slave). We record arm movements using IMU sensors, and calculate human forward kinematics to be mapped on robot movements. In order to solve robot kinematic redundancy, we implemented different algorithms for inverse kinematics that allows imposing anthropomorphism criteria on robot movements. The main objective is to let the user to control the robotic platform in an easy and intuitive manner by providing the control input freely moving his/her own arm and exploiting redundancy and anthropomorphism criteria in order to achieve humanlike behaviour on the robot arm. Therefore, three inverse kinematics algorithms are implemented: Damped Least Squares (DLS), Elastic Potential (EP) and Augmented Jacobian (AJ). In order to evaluate the performance of the algorithms, four healthy subjects have been asked to control the motion of an anthropomorphic robot arm (i.e. the Kuka Light Weight Robot 4+) through four magneto-inertial sensors (i.e. Xsens Wireless Motion Tracking sensors - MTw) positioned on their arm. Anthropomorphism indices and position and orientation errors between the human hand pose and the robot end-effector pose were evaluated to assess the performance of our approach.

Whether working together to move a table or supporting a child learning to ride a bike, physically connected individuals exchange haptic information to improve motor performance. However, this improvement occurs at the cost of additional effort for the more skilled partner. Objective: Here, we hypothesize that an asymmetric connection, consisting of a stiffer link to the less skilled partner and a more compliant link to the more skilled partner, could improve task performance without additional effort in collaborative tasks. Methods: Through computational modelling, we first tested this hypothesis on simulated human dyads tracking a common target. Then we experimentally validated the approach on a three degree-of-freedom tracking task using two commercial robots as individual interfaces. Results: The simulation and experimental results confirm that using an asymmetric connection stiffness can improve joint performance without requiring additional effort from either partner compared to their solo effort. Conclusion: This suggests that the training of motor skills with a proficient partner may be enhanced through the use of robot-mediated asymmetric haptic connections. Significance:This approach may benefit joint tasks between individuals with clearly different motor abilities, such as a violin teacher demonstrating bowing techniques or a physical therapist assisting a patient during rehabilitation.

Neurorehabilitation conventionally relies on the interaction between a patient and a physical therapist. Robotic systems can improve and enrich the physical feedback provided to patients after neurological injury, but they under-utilize the adaptability and clinical expertise of trained therapists. In this position paper, we advocate for a novel approach that integrates the therapist’s clinical expertise and nuanced decision-making with the strength, accuracy, and repeatability of robotics: Robot-mediated physical Human–Human Interaction. This framework, which enables two individuals to physically interact through robotic devices, has been studied across diverse research groups and has recently emerged as a promising link between conventional manual therapy and rehabilitation robotics, harmonizing the strengths of both approaches. Although current findings are largely based on pilot studies and conceptual frameworks, integrating therapists’ expertise with the functionalities offered by robotic systems represents a promising direction for improving rehabilitation outcomes. This paper presents the rationale of a multidisciplinary team—including engineers, doctors, and physical therapists—for conducting research that utilizes: a unified taxonomy to describe robot-mediated rehabilitation, a framework of interaction based on social psychology, and a technological approach that makes robotic systems seamless facilitators of natural human-human interaction.